Cochrane · systematic review · CD011277

Alginate dressings for treating pressure ulcers

Dumville, JC, Keogh, SJ, Liu, Z, et al. · Cochrane Database of Systematic Reviews · 2015 · Cochrane Library

WoundsAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
11
current version
GRADE rated
11
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 10 · 90.9%Low 1 · 9.1%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Alginate dressing followed by hydrocolloid dressing compared with hydrocolloid dressing alone

Population: patients with pressure ulcers
3 questions
OutcomeEffectEvidenceStatus / GRADE
Change in wound size
Alginate dressing followed by hydrocolloid dressing vs hydrocolloid dressing alone
no estimate extracted1 study · 110 participantsVery low
Downgraded: indirectness
Wound infection
Alginate dressing followed by hydrocolloid dressing vs hydrocolloid dressing alone
RR 2.79 [0.12, 67.1]1 study · 110 participantsVery low
Downgraded: imprecision
Adverse events
Alginate dressing followed by hydrocolloid dressing vs hydrocolloid dressing alone
RR 1.12 [0.36, 3.44]1 study · 110 participantsLow
Downgraded: imprecision

Comparison between different alginates

Population: patients with pressure ulcers
2 questions
OutcomeEffectEvidenceStatus / GRADE
Complete wound healing
RR 1.5 [0.17, 12.94]1 study · 36 participantsVery low
Downgraded: risk of bias, imprecision
Adverse events
RR 0.5 [0.12, 2.12]1 study · 36 participantsVery low
Downgraded: risk of bias, imprecision

Alginate compared with dextranomer paste

Population: patients with pressure ulcers
2 questions
OutcomeEffectEvidenceStatus / GRADE
Wound infection
Alginate vs dextranomer paste
RR 0.96 [0.14, 6.51]1 study · 92 participantsVery low
Downgraded: imprecision
Adverse events
Alginate vs dextranomer paste
RR 0.38 [0.13, 1.13]1 study · 92 participantsVery low
Downgraded: imprecision

Silver‐alginate compared with plain alginate

Population: patients with pressure ulcers
2 questions
OutcomeEffectEvidenceStatus / GRADE
Change in wound size
Silver‐alginate vs plain alginate
no estimate extracted1 study · 110 participantsVery low
Downgraded: imprecision, indirectness
Wound infection
Silver‐alginate vs plain alginate
no estimate extracted1 study · 28 participantsVery low
Downgraded: imprecision

Alginate compared with radiant heat system

Population: patients with pressure ulcers
2 questions
OutcomeEffectEvidenceStatus / GRADE
Change in wound size
Alginate vs radiant heat system
no estimate extracted1 study · 1105 participantsVery low
Downgraded: risk of bias, imprecision, indirectness
Adverse event (pain)
Alginate vs radiant heat system
no estimate extracted1 study · 50 participantsVery low
Downgraded: risk of bias, imprecision