Cochrane · systematic review · CD008990

Recombinant human growth hormone for treating burns and donor sites

Breederveld, RS, Tuinebreijer, WE · Cochrane Database of Systematic Reviews · 2014 · Cochrane Library

Wounds2 versionsAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
7
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 7 · 100%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Show all 2 versions

Recombinant human growth hormone compared with placebo for treating burns and donor sites

7 questions
OutcomeEffectEvidenceStatus / GRADE
Healing time of burn wounds in days for adults
Recombinant human growth hormone vs placebo
no estimate extracted2 studies · 36 participantsLow
Downgraded: risk of bias, imprecision
Donor site healing time in days for adults
Recombinant human growth hormone vs placebo
no estimate extracted2 studies · 36 participantsLow
Downgraded: risk of bias, imprecision
Donor site healing time in days for children
Recombinant human growth hormone vs placebo
no estimate extracted2 studies · 73 participantsLow
Downgraded: risk of bias, imprecision
Mortality in adults and children
Recombinant human growth hormone vs placebo
RR 0.53 [0.22, 1.29]5 studies · 324 participantsLow
Downgraded: risk of bias
Septicaemia in adults
Recombinant human growth hormone vs placebo
RR 0.61 [0.31, 1.22]4 studies · 267 participantsLow
Downgraded: risk of bias
Hyperglycaemia in adults and children
Recombinant human growth hormone vs placebo
RR 2.65 [1.68, 4.16]5 studies · 340 participantsLow
Downgraded: risk of bias, imprecision
Length of hospital stay in days for adults
Recombinant human growth hormone vs placebo
no estimate extracted4 studies · 99 participantsLow
Downgraded: risk of bias, imprecision