Cochrane Review Group

Musculoskeletal

143 systematic reviews in Musculoskeletal ask 1,956 questions. 28.4% have no studies to answer them, 13% rest on very low certainty evidence and 24.8% reach moderate or high certainty.

Reviews
143
Questions
1,956
current versions
No studies
28.4%
Moderate or high
24.8%
No studies 555 · 28.4%Ungraded 107 · 5.5%Very low 255 · 13%Low 555 · 28.4%Moderate 357 · 18.3%High 127 · 6.5%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
Methotrexate vs placebo
Outcomes(time frame of absolute effects) · children and young people with JIA
Methotrexate for juvenile idiopathic arthritis (2024) · Cochrane
no estimate extractedNRNo studies
Oral methotrexate plus intra‐articular glucocorticoid vs intra‐articular glucocorticoid alone
Treatment responsea · children and young people with JIA
Methotrexate for juvenile idiopathic arthritis (2024) · Cochrane
no estimate extractedNRNo studies
Oral methotrexate plus intra‐articular glucocorticoid vs intra‐articular glucocorticoid alone
Function · children and young people with JIA
Methotrexate for juvenile idiopathic arthritis (2024) · Cochrane
no estimate extractedNRNo studies
Oral methotrexate plus intra‐articular glucocorticoid vs intra‐articular glucocorticoid alone
Pain · children and young people with JIA
Methotrexate for juvenile idiopathic arthritis (2024) · Cochrane
no estimate extractedNRNo studies
Oral methotrexate plus intra‐articular glucocorticoid vs intra‐articular glucocorticoid alone
Participant global assessment of well‐being · children and young people with JIA
Methotrexate for juvenile idiopathic arthritis (2024) · Cochrane
no estimate extractedNRNo studies
Oral methotrexate plus intra‐articular glucocorticoid vs intra‐articular glucocorticoid alone
Serious adverse events(12 months) · children and young people with JIA
Methotrexate for juvenile idiopathic arthritis (2024) · Cochrane
no estimate extractedNRVery low
Methotrexate vs alternative disease‐modifying antirheumatic drugs
Outcomes(time frame of absolute effects) · children and young people with JIA
Methotrexate for juvenile idiopathic arthritis (2024) · Cochrane
no estimate extractedNRNo studies
Methotrexate vs alternative disease‐modifying antirheumatic drugs
Sustained clinically inactive diseasec · children and young people with JIA
Methotrexate for juvenile idiopathic arthritis (2024) · Cochrane
no estimate extractedNRNo studies
Methotrexate vs alternative disease‐modifying antirheumatic drugs
Pain · children and young people with JIA
Methotrexate for juvenile idiopathic arthritis (2024) · Cochrane
no estimate extractedNRNo studies
Methotrexate vs placebo
Sustained clinically inactive diseasec · children and young people with JIA
Methotrexate for juvenile idiopathic arthritis (2024) · Cochrane
no estimate extractedNRNo studies
Methotrexate vs placebo
Function · children and young people with JIA
Methotrexate for juvenile idiopathic arthritis (2024) · Cochrane
no estimate extractedNRNo studies
Oral methotrexate plus intra‐articular glucocorticoid vs intra‐articular glucocorticoid alone
Outcomes(time frame of absolute effects) · children and young people with JIA
Methotrexate for juvenile idiopathic arthritis (2024) · Cochrane
no estimate extractedNRNo studies

Reviews 143

Hyaluronic acid and other conservative treatment options for osteoarthritis of the ankle

Witteveen, AGH, Hofstad, CJ, et al. · Cochrane Database of Systematic Reviews · 2015
CochraneSoF table
6 questions

Non‐steroidal anti‐inflammatory drugs (NSAIDs) for axial spondyloarthritis (ankylosing spondylitis and non‐radiographic axial spondyloarthritis)

Kroon, FPB, van der Burg, LRA, et al. · Cochrane Database of Systematic Reviews · 2015
CochraneSoF table
14 questions

Selective serotonin reuptake inhibitors for fibromyalgia syndrome

Walitt, B, Urrútia, G, et al. · Cochrane Database of Systematic Reviews · 2015
CochraneSoF table
7 questions

Methotrexate for treating rheumatoid arthritis

Lopez‐Olivo, MA, Siddhanamatha, HR, et al. · Cochrane Database of Systematic Reviews · 2014
CochraneSoF table
7 questions

Oral herbal therapies for treating osteoarthritis

Cameron, M, Chrubasik, S · Cochrane Database of Systematic Reviews · 2014
CochraneSoF table
56 questions

Oral or transdermal opioids for osteoarthritis of the knee or hip

da Costa, BR, Nüesch, E, et al. · Cochrane Database of Systematic Reviews · 2014
CochraneSoF table
6 questions

Preoperative education for hip or knee replacement

McDonald, S, Page, MJ, et al. · Cochrane Database of Systematic Reviews · 2014
CochraneSoF table
14 questions

Deep transverse friction massage for treating lateral elbow or lateral knee tendinitis

Loew, LM, Brosseau, L, et al. · Cochrane Database of Systematic Reviews · 2014
CochraneSoF table
21 questions

Osteotomy for treating knee osteoarthritis

Brouwer, RW, Huizinga, MR, et al. · Cochrane Database of Systematic Reviews · 2014
CochraneSoF table
14 questions

Continuous passive motion following total knee arthroplasty in people with arthritis

Harvey, LA, Brosseau, L, et al. · Cochrane Database of Systematic Reviews · 2014
CochraneSoF table
7 questions

Sulfasalazine for ankylosing spondylitis

Chen, J, Lin, S, et al. · Cochrane Database of Systematic Reviews · 2014
CochraneSoF table
7 questions

Diacerein for osteoarthritis

Fidelix, TS, Macedo, CR, et al. · Cochrane Database of Systematic Reviews · 2014
CochraneSoF table
7 questions

Chinese herbal medicines for treating osteoporosis

Liu, Y, Liu, JP, et al. · Cochrane Database of Systematic Reviews · 2014
CochraneSoF table
28 questions

Allopurinol for chronic gout

Seth, R, Kydd, ASR, et al. · Cochrane Database of Systematic Reviews · 2014
CochraneSoF table
21 questions

Exercise for osteoarthritis of the hip

Fransen, M, McConnell, S, et al. · Cochrane Database of Systematic Reviews · 2014
CochraneSoF table
8 questions

Self‐management education programmes for osteoarthritis

Kroon, FPB, van der Burg, LRA, et al. · Cochrane Database of Systematic Reviews · 2014
CochraneSoF table
28 questions

Interleukin‐1 inhibitors for acute gout

Sivera, F, Wechalekar, MD, et al. · Cochrane Database of Systematic Reviews · 2014
CochraneSoF table
14 questions

Uricosuric medications for chronic gout

Kydd, ASR, Seth, R, et al. · Cochrane Database of Systematic Reviews · 2014
CochraneSoF table
21 questions

Manual therapy and exercise for adhesive capsulitis (frozen shoulder)

Page, MJ, Green, S, et al. · Cochrane Database of Systematic Reviews · 2014
CochraneSoF table
42 questions

Electrotherapy modalities for adhesive capsulitis (frozen shoulder)

Page, MJ, Green, S, et al. · Cochrane Database of Systematic Reviews · 2014
CochraneSoF table
21 questions

Aquatic exercise training for fibromyalgia

Bidonde, J, Busch, AJ, et al. · Cochrane Database of Systematic Reviews · 2014
CochraneSoF table
14 questions

Erythropoiesis‐stimulating agents for anemia in rheumatoid arthritis

Martí‐Carvajal, AJ, Agreda‐Pérez, LH, et al. · Cochrane Database of Systematic Reviews · 2013
CochraneSoF table
7 questions

Folic acid and folinic acid for reducing side effects in patients receiving methotrexate for rheumatoid arthritis

Shea, B, Swinden, MV, et al. · Cochrane Database of Systematic Reviews · 2013
CochraneSoF table
21 questions

Cyclophosphamide versus methylprednisolone for treating neuropsychiatric involvement in systemic lupus erythematosus

Fernandes Moça Trevisani, V, Castro, AA, et al. · Cochrane Database of Systematic Reviews · 2013
CochraneSoF table
7 questions

Electromagnetic fields for treating osteoarthritis

Li, S, Yu, B, et al. · Cochrane Database of Systematic Reviews · 2013
CochraneSoF table
6 questions