Cochrane Review Group

Musculoskeletal

143 systematic reviews in Musculoskeletal ask 1,956 questions. 28.4% have no studies to answer them, 13% rest on very low certainty evidence and 24.8% reach moderate or high certainty.

Reviews
143
Questions
1,956
current versions
No studies
28.4%
Moderate or high
24.8%
No studies 555 · 28.4%Ungraded 107 · 5.5%Very low 255 · 13%Low 555 · 28.4%Moderate 357 · 18.3%High 127 · 6.5%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
Methotrexate vs placebo
Outcomes(time frame of absolute effects) · children and young people with JIA
Methotrexate for juvenile idiopathic arthritis (2024) · Cochrane
no estimate extractedNRNo studies
Oral methotrexate plus intra‐articular glucocorticoid vs intra‐articular glucocorticoid alone
Treatment responsea · children and young people with JIA
Methotrexate for juvenile idiopathic arthritis (2024) · Cochrane
no estimate extractedNRNo studies
Oral methotrexate plus intra‐articular glucocorticoid vs intra‐articular glucocorticoid alone
Function · children and young people with JIA
Methotrexate for juvenile idiopathic arthritis (2024) · Cochrane
no estimate extractedNRNo studies
Oral methotrexate plus intra‐articular glucocorticoid vs intra‐articular glucocorticoid alone
Pain · children and young people with JIA
Methotrexate for juvenile idiopathic arthritis (2024) · Cochrane
no estimate extractedNRNo studies
Oral methotrexate plus intra‐articular glucocorticoid vs intra‐articular glucocorticoid alone
Participant global assessment of well‐being · children and young people with JIA
Methotrexate for juvenile idiopathic arthritis (2024) · Cochrane
no estimate extractedNRNo studies
Oral methotrexate plus intra‐articular glucocorticoid vs intra‐articular glucocorticoid alone
Serious adverse events(12 months) · children and young people with JIA
Methotrexate for juvenile idiopathic arthritis (2024) · Cochrane
no estimate extractedNRVery low
Methotrexate vs alternative disease‐modifying antirheumatic drugs
Outcomes(time frame of absolute effects) · children and young people with JIA
Methotrexate for juvenile idiopathic arthritis (2024) · Cochrane
no estimate extractedNRNo studies
Methotrexate vs alternative disease‐modifying antirheumatic drugs
Sustained clinically inactive diseasec · children and young people with JIA
Methotrexate for juvenile idiopathic arthritis (2024) · Cochrane
no estimate extractedNRNo studies
Methotrexate vs alternative disease‐modifying antirheumatic drugs
Pain · children and young people with JIA
Methotrexate for juvenile idiopathic arthritis (2024) · Cochrane
no estimate extractedNRNo studies
Methotrexate vs placebo
Sustained clinically inactive diseasec · children and young people with JIA
Methotrexate for juvenile idiopathic arthritis (2024) · Cochrane
no estimate extractedNRNo studies
Methotrexate vs placebo
Function · children and young people with JIA
Methotrexate for juvenile idiopathic arthritis (2024) · Cochrane
no estimate extractedNRNo studies
Oral methotrexate plus intra‐articular glucocorticoid vs intra‐articular glucocorticoid alone
Outcomes(time frame of absolute effects) · children and young people with JIA
Methotrexate for juvenile idiopathic arthritis (2024) · Cochrane
no estimate extractedNRNo studies

Reviews 143

Vitamin D supplementation for improving bone mineral density in children

Winzenberg, TM, Powell, S, et al. · Cochrane Database of Systematic Reviews · 2010
CochraneSoF table
5 questions

Surface neuromuscular electrical stimulation for quadriceps strengthening pre and post total knee replacement

Monaghan, B, Caulfield, B, et al. · Cochrane Database of Systematic Reviews · 2010
CochraneSoF table
6 questions

Joint lavage for osteoarthritis of the knee

Reichenbach, S, Rutjes, AWS, et al. · Cochrane Database of Systematic Reviews · 2010
CochraneSoF table
7 questions

Balance training (proprioceptive training) for patients with rheumatoid arthritis

Silva, KNG, Mizusaki Imoto, A, et al. · Cochrane Database of Systematic Reviews · 2010
CochraneSoF table
7 questions

Interventions for treating osteoarthritis of the big toe joint

Zammit, GV, Menz, HB, et al. · Cochrane Database of Systematic Reviews · 2010
CochraneSoF table
3 questions

Surgery for shoulder osteoarthritis

Singh, JA, Sperling, J, et al. · Cochrane Database of Systematic Reviews · 2010
CochraneSoF table
6 questions

Botulinum toxin for shoulder pain

Singh, JA, Fitzgerald, PM · Cochrane Database of Systematic Reviews · 2010
CochraneSoF table
5 questions

Tocilizumab for rheumatoid arthritis

Singh, JA, Beg, S, et al. · Cochrane Database of Systematic Reviews · 2010
CochraneSoF table
7 questions

Golimumab for rheumatoid arthritis

Singh, JA, Noorbaloochi, S, et al. · Cochrane Database of Systematic Reviews · 2010
CochraneSoF table
7 questions

Methotrexate monotherapy versus methotrexate combination therapy with non‐biologic disease modifying anti‐rheumatic drugs for rheumatoid arthritis

Katchamart, W, Trudeau, J, et al. · Cochrane Database of Systematic Reviews · 2010
CochraneSoF table
7 questions

Transcutaneous electrostimulation for osteoarthritis of the knee

Rutjes, AWS, Nüesch, E, et al. · Cochrane Database of Systematic Reviews · 2009
CochraneSoF table
5 questions

Topical glyceryl trinitrate for rotator cuff disease

Cumpston, M, Johnston, RV, et al. · Cochrane Database of Systematic Reviews · 2009
CochraneSoF table
19 questions

Assistive technology for rheumatoid arthritis

Tuntland, H, Kjeken, I, et al. · Cochrane Database of Systematic Reviews · 2009
CochraneSoF table
7 questions

Dynamic exercise programs (aerobic capacity and/or muscle strength training) in patients with rheumatoid arthritis

Hurkmans, E, van der Giesen, FJ, et al. · Cochrane Database of Systematic Reviews · 2009
CochraneSoF table
23 questions

Abatacept for rheumatoid arthritis

Maxwell, L, Singh, JA · Cochrane Database of Systematic Reviews · 2009
CochraneSoF table
7 questions

S‐Adenosylmethionine for osteoarthritis of the knee or hip

Rutjes, AWS, Nüesch, E, et al. · Cochrane Database of Systematic Reviews · 2009
CochraneSoF table
5 questions

Glucosamine therapy for treating osteoarthritis

Towheed, T, Maxwell, L, et al. · Cochrane Database of Systematic Reviews · 2005
CochraneSoF table
9 questions

Leflunomide for the treatment of rheumatoid arthritis

Osiri, M, Shea, B, et al. · Cochrane Database of Systematic Reviews · 2002
CochraneSoF table
11 questions