Cochrane · systematic review · CD006944

Vitamin D supplementation for improving bone mineral density in children

Winzenberg, TM, Powell, S, Shaw, KA, et al. · Cochrane Database of Systematic Reviews · 2010 · Cochrane Library

MusculoskeletalAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
5
current version
GRADE rated
4
No studies
1
Included studies
NR
No studies 1 · 20%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 2 · 40%High 2 · 40%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Vitamin D supplementation for improving bone mineral density in children

Population: patients with improving bone mineral density in children
5 questions
OutcomeEffectEvidenceStatus / GRADE
% Change total body bone mineral content from baseline
no estimate extracted5 studies · 672 participantsHigh
% Change hip bone mineral density from baseline
no estimate extracted4 studies · 639 participantsModerate
Downgraded: inconsistency
% Change lumbar spine bone mineral density from baseline
no estimate extracted5 studies · 660 participantsHigh
% Change forearm bone mineral density from baseline
no estimate extracted3 studies · 427 participantsModerate
Downgraded: inconsistency
Adverse events3 ‐ not reported
no estimate extractedNRNo studies