Cochrane Review Group

Musculoskeletal

143 systematic reviews in Musculoskeletal ask 1,956 questions. 28.4% have no studies to answer them, 13% rest on very low certainty evidence and 24.8% reach moderate or high certainty.

Reviews
143
Questions
1,956
current versions
No studies
28.4%
Moderate or high
24.8%
No studies 555 · 28.4%Ungraded 107 · 5.5%Very low 255 · 13%Low 555 · 28.4%Moderate 357 · 18.3%High 127 · 6.5%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
Methotrexate vs placebo
Outcomes(time frame of absolute effects) · children and young people with JIA
Methotrexate for juvenile idiopathic arthritis (2024) · Cochrane
no estimate extractedNRNo studies
Oral methotrexate plus intra‐articular glucocorticoid vs intra‐articular glucocorticoid alone
Treatment responsea · children and young people with JIA
Methotrexate for juvenile idiopathic arthritis (2024) · Cochrane
no estimate extractedNRNo studies
Oral methotrexate plus intra‐articular glucocorticoid vs intra‐articular glucocorticoid alone
Function · children and young people with JIA
Methotrexate for juvenile idiopathic arthritis (2024) · Cochrane
no estimate extractedNRNo studies
Oral methotrexate plus intra‐articular glucocorticoid vs intra‐articular glucocorticoid alone
Pain · children and young people with JIA
Methotrexate for juvenile idiopathic arthritis (2024) · Cochrane
no estimate extractedNRNo studies
Oral methotrexate plus intra‐articular glucocorticoid vs intra‐articular glucocorticoid alone
Participant global assessment of well‐being · children and young people with JIA
Methotrexate for juvenile idiopathic arthritis (2024) · Cochrane
no estimate extractedNRNo studies
Oral methotrexate plus intra‐articular glucocorticoid vs intra‐articular glucocorticoid alone
Serious adverse events(12 months) · children and young people with JIA
Methotrexate for juvenile idiopathic arthritis (2024) · Cochrane
no estimate extractedNRVery low
Methotrexate vs alternative disease‐modifying antirheumatic drugs
Outcomes(time frame of absolute effects) · children and young people with JIA
Methotrexate for juvenile idiopathic arthritis (2024) · Cochrane
no estimate extractedNRNo studies
Methotrexate vs alternative disease‐modifying antirheumatic drugs
Sustained clinically inactive diseasec · children and young people with JIA
Methotrexate for juvenile idiopathic arthritis (2024) · Cochrane
no estimate extractedNRNo studies
Methotrexate vs alternative disease‐modifying antirheumatic drugs
Pain · children and young people with JIA
Methotrexate for juvenile idiopathic arthritis (2024) · Cochrane
no estimate extractedNRNo studies
Methotrexate vs placebo
Sustained clinically inactive diseasec · children and young people with JIA
Methotrexate for juvenile idiopathic arthritis (2024) · Cochrane
no estimate extractedNRNo studies
Methotrexate vs placebo
Function · children and young people with JIA
Methotrexate for juvenile idiopathic arthritis (2024) · Cochrane
no estimate extractedNRNo studies
Oral methotrexate plus intra‐articular glucocorticoid vs intra‐articular glucocorticoid alone
Outcomes(time frame of absolute effects) · children and young people with JIA
Methotrexate for juvenile idiopathic arthritis (2024) · Cochrane
no estimate extractedNRNo studies

Reviews 143

Methotrexate for juvenile idiopathic arthritis

Tan, J, Renton, WD, et al. · Cochrane Database of Systematic Reviews · 2024
CochraneSoF table
24 questions

Etidronate for the primary and secondary prevention of osteoporotic fractures in postmenopausal women

Wells, GA, Hsieh, S-C, et al. · Cochrane Database of Systematic Reviews · 2024
CochraneSoF table
12 questions

Manual therapy and exercise for lateral elbow pain

Wallis, JA, Bourne, AM, et al. · Cochrane Database of Systematic Reviews · 2024
CochraneSoF table
14 questions

Cryotherapy following total knee replacement

Aggarwal, A, Adie, S, et al. · Cochrane Database of Systematic Reviews · 2023
CochraneSoF table
7 questions

The McKenzie method for (sub)acute non‐specific low back pain

Almeida, MO, Narciso Garcia, A, et al. · Cochrane Database of Systematic Reviews · 2023
CochraneSoF table
15 questions

Calcium and vitamin D for increasing bone mineral density in premenopausal women

Méndez-Sánchez, L, Clark, P, et al. · Cochrane Database of Systematic Reviews · 2023
CochraneSoF table
21 questions

Phosphodiesterase 5 inhibitors (PDE5i) for the treatment of Raynaud's phenomenon

Maltez, N, Maxwell, LJ, et al. · Cochrane Database of Systematic Reviews · 2023
CochraneSoF table
7 questions

Exercise as adjunctive therapy for systemic lupus erythematosus

Frade, S, O'Neill, S, et al. · Cochrane Database of Systematic Reviews · 2023
CochraneSoF table
21 questions

Risedronate for the primary and secondary prevention of osteoporotic fractures in postmenopausal women

Wells, GA, Hsieh, S-C, et al. · Cochrane Database of Systematic Reviews · 2022
CochraneSoF table
12 questions

Exercise for acutely hospitalised older medical patients

Hartley, P, Keating, JL, et al. · Cochrane Database of Systematic Reviews · 2022
CochraneSoF table
28 questions

Foot orthoses for treating paediatric flat feet

Evans, AM, Rome, K, et al. · Cochrane Database of Systematic Reviews · 2022
CochraneSoF table
52 questions

Mobility training for increasing mobility and functioning in older people with frailty

Treacy, D, Hassett, L, et al. · Cochrane Database of Systematic Reviews · 2022
CochraneSoF table
12 questions

Stem cell transplantation for systemic sclerosis

Bruera, S, Sidanmat, H, et al. · Cochrane Database of Systematic Reviews · 2022
CochraneSoF table
21 questions

Adjunctive therapies in addition to land‐based exercise therapy for osteoarthritis of the hip or knee

French, HP, Abbott, JH, et al. · Cochrane Database of Systematic Reviews · 2022
CochraneSoF table
14 questions

Antidepressants for hip and knee osteoarthritis

Leaney, AA, Lyttle, JR, et al. · Cochrane Database of Systematic Reviews · 2022
CochraneSoF table
7 questions

Arthroscopic surgery for degenerative knee disease (osteoarthritis including degenerative meniscal tears)

O'Connor, D, Johnston, RV, et al. · Cochrane Database of Systematic Reviews · 2022
CochraneSoF table
7 questions

Colchicine for acute gout

McKenzie, BJ, Wechalekar, MD, et al. · Cochrane Database of Systematic Reviews · 2021
CochraneSoF table
28 questions

Image‐guided glucocorticoid injection versus injection without image guidance for shoulder pain

Zadro, J, Rischin, A, et al. · Cochrane Database of Systematic Reviews · 2021
CochraneSoF table
7 questions

Interventions for tophi in gout

Sriranganathan, MK, Vinik, O, et al. · Cochrane Database of Systematic Reviews · 2021
CochraneSoF table
24 questions

Non‐steroidal anti‐inflammatory drugs for acute gout

van Durme, CMPG, Wechalekar, MD, et al. · Cochrane Database of Systematic Reviews · 2021
CochraneSoF table
21 questions

Dietary supplements for chronic gout

Andrés, M, Sivera, F, et al. · Cochrane Database of Systematic Reviews · 2021
CochraneSoF table
14 questions

Belimumab for systemic lupus erythematosus

Singh, JA, Shah, NP, et al. · Cochrane Database of Systematic Reviews · 2021
CochraneSoF table
7 questions

Autologous blood and platelet‐rich plasma injection therapy for lateral elbow pain

Karjalainen, TV, Silagy, M, et al. · Cochrane Database of Systematic Reviews · 2021
CochraneSoF table
7 questions

Kinesio taping for rotator cuff disease

Gianola, S, Iannicelli, V, et al. · Cochrane Database of Systematic Reviews · 2021
CochraneSoF table
14 questions

Non‐steroidal anti‐inflammatory drugs (NSAIDs) for trigger finger

Leow, MQ, Zheng, Q, et al. · Cochrane Database of Systematic Reviews · 2021
CochraneSoF table
7 questions