Cochrane · systematic review · CD010951
Autologous blood and platelet‐rich plasma injection therapy for lateral elbow pain
Karjalainen, TV, Silagy, M, O'Bryan, E, et al. · Cochrane Database of Systematic Reviews · 2021 · Cochrane Library
MusculoskeletalAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
5
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 2 · 28.6%Very low 2 · 28.6%Low 1 · 14.3%Moderate 2 · 28.6%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Autologous blood or PRP versus placebo at 3 months' follow‐up
Population: lateral elbow pain
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Pain (VAS, PRTEE) translated to 0 to 10, where 0 is no pain Autologous blood or PRP vs placebo at 3 months' follow‐up | no estimate extracted | 8 studies · 523 participants | Moderate Downgraded: risk of bias, imprecision, indirectness |
Function (PRTEE, DASH, MMCPIE, Roles‐Maudsley), translated to 0 to 100, where 0 is best function, or no disability Autologous blood or PRP vs placebo at 3 months' follow‐up | no estimate extracted | 8 studies · 502 participants | Moderate Downgraded: risk of bias, imprecision, indirectness |
Treatment success (> 25% improvement in pain or function) Autologous blood or PRP vs placebo at 3 months' follow‐up | RR 1 [0.83, 1.19] | 4 studies · 372 participants | Very low Downgraded: risk of bias, imprecision, indirectness |
Health‐related quality of life Not measured Autologous blood or PRP vs placebo at 3 months' follow‐up | no estimate extracted | 0 studies · 0 participants | Ungraded |
Pain relief ≥ 30% or ≥ 50% Not measured at 3 months Autologous blood or PRP vs placebo at 3 months' follow‐up | no estimate extracted | 0 studies · 0 participants | Ungraded |
Withdrawal due to adverse events  Autologous blood or PRP vs placebo at 3 months' follow‐up | RR 0.32 [0.03, 2.92] | 1 study · 80 participants | Very low Downgraded: risk of bias, imprecision, indirectness |
Adverse events (pain and swelling at injection site and limitation of elbow movement following injection) Autologous blood or PRP vs placebo at 3 months' follow‐up | RR 1.14 [0.76, 1.72] | 5 studies · 425 participants | Low Downgraded: risk of bias, imprecision, indirectness |