Cochrane Review Group

Musculoskeletal

143 systematic reviews in Musculoskeletal ask 1,956 questions. 28.4% have no studies to answer them, 13% rest on very low certainty evidence and 24.8% reach moderate or high certainty.

Reviews

143

Questions

1,956

current versions

No studies

28.4%

Moderate or high

24.8%

No studies 555 · 28.4%Ungraded 107 · 5.5%Very low 255 · 13%Low 555 · 28.4%Moderate 357 · 18.3%High 127 · 6.5%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Search questions in Musculoskeletal

Thinnest evidence

All no studies and very low questions

Question	Effect	Evidence	Status / GRADE
Methotrexate vs placebo Outcomes(time frame of absolute effects) · children and young people with JIA Methotrexate for juvenile idiopathic arthritis (2024) · Cochrane	no estimate extracted	NR	No studies
Oral methotrexate plus intra‐articular glucocorticoid vs intra‐articular glucocorticoid alone Treatment responsea · children and young people with JIA Methotrexate for juvenile idiopathic arthritis (2024) · Cochrane	no estimate extracted	NR	No studies
Oral methotrexate plus intra‐articular glucocorticoid vs intra‐articular glucocorticoid alone Function · children and young people with JIA Methotrexate for juvenile idiopathic arthritis (2024) · Cochrane	no estimate extracted	NR	No studies
Oral methotrexate plus intra‐articular glucocorticoid vs intra‐articular glucocorticoid alone Pain · children and young people with JIA Methotrexate for juvenile idiopathic arthritis (2024) · Cochrane	no estimate extracted	NR	No studies
Oral methotrexate plus intra‐articular glucocorticoid vs intra‐articular glucocorticoid alone Participant global assessment of well‐being · children and young people with JIA Methotrexate for juvenile idiopathic arthritis (2024) · Cochrane	no estimate extracted	NR	No studies
Oral methotrexate plus intra‐articular glucocorticoid vs intra‐articular glucocorticoid alone Serious adverse events(12 months) · children and young people with JIA Methotrexate for juvenile idiopathic arthritis (2024) · Cochrane	no estimate extracted	NR	Very low
Methotrexate vs alternative disease‐modifying antirheumatic drugs Outcomes(time frame of absolute effects) · children and young people with JIA Methotrexate for juvenile idiopathic arthritis (2024) · Cochrane	no estimate extracted	NR	No studies
Methotrexate vs alternative disease‐modifying antirheumatic drugs Sustained clinically inactive diseasec · children and young people with JIA Methotrexate for juvenile idiopathic arthritis (2024) · Cochrane	no estimate extracted	NR	No studies
Methotrexate vs alternative disease‐modifying antirheumatic drugs Pain · children and young people with JIA Methotrexate for juvenile idiopathic arthritis (2024) · Cochrane	no estimate extracted	NR	No studies
Methotrexate vs placebo Sustained clinically inactive diseasec · children and young people with JIA Methotrexate for juvenile idiopathic arthritis (2024) · Cochrane	no estimate extracted	NR	No studies
Methotrexate vs placebo Function · children and young people with JIA Methotrexate for juvenile idiopathic arthritis (2024) · Cochrane	no estimate extracted	NR	No studies
Oral methotrexate plus intra‐articular glucocorticoid vs intra‐articular glucocorticoid alone Outcomes(time frame of absolute effects) · children and young people with JIA Methotrexate for juvenile idiopathic arthritis (2024) · Cochrane	no estimate extracted	NR	No studies

Reviews 143

Stretch for the treatment and prevention of contractures

Harvey, LA, Katalinic, OM, et al. · Cochrane Database of Systematic Reviews · 2017

Musculoskeletal

Thinnest evidence

Reviews 143

Stretch for the treatment and prevention of contractures

Certolizumab pegol (CDP870) for rheumatoid arthritis in adults

Celecoxib for osteoarthritis

Exercise for hand osteoarthritis

Whole body vibration exercise training for fibromyalgia

Celecoxib for rheumatoid arthritis

Aerobic exercise training for adults with fibromyalgia

Bisphosphonates for steroid‐induced osteoporosis

Aquatic exercise for the treatment of knee and hip osteoarthritis

Biologic interventions for fatigue in rheumatoid arthritis

Assistive devices, hip precautions, environmental modifications and training to prevent dislocation and improve function after hip arthroplasty

Manual therapy and exercise for rotator cuff disease

Electrotherapy modalities for rotator cuff disease

Balneotherapy (or spa therapy) for rheumatoid arthritis

Mind and body therapy for fibromyalgia

Mobile bearing vs fixed bearing prostheses for posterior cruciate retaining total knee arthroplasty for postoperative functional status in patients with osteoarthritis and rheumatoid arthritis

Braces and orthoses for treating osteoarthritis of the knee

Exercise for osteoarthritis of the knee

Surgery for thumb (trapeziometacarpal joint) osteoarthritis

Intra‐articular corticosteroid for knee osteoarthritis

TNF‐alpha inhibitors for ankylosing spondylitis

Chondroitin for osteoarthritis

Rituximab for rheumatoid arthritis

Surgery for Dupuytren's contracture of the fingers

High‐intensity versus low‐intensity physical activity or exercise in people with hip or knee osteoarthritis