Cochrane · systematic review · CD010203

High‐intensity versus low‐intensity physical activity or exercise in people with hip or knee osteoarthritis

Regnaux, JP, Lefevre‐Colau, MM, Trinquart, L, et al. · Cochrane Database of Systematic Reviews · 2015 · Cochrane Library

MusculoskeletalAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
9
current version
GRADE rated
8
No studies
1
Included studies
NR
No studies 1 · 11.1%Ungraded 0 · 0%Very low 5 · 55.6%Low 3 · 33.3%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Summary of findings table: Physical activity and exercise programs in osteoarthritis

Population: People with hip or knee osteoarthritis
5 questions
OutcomeEffectEvidenceStatus / GRADE
Pain (at study completion) WOMAC (VAS or NRS) from 0 to 20; lower scores mean reduced pain
no estimate extracted4 studies · 313 participantsLow
Downgraded: risk of bias, imprecision
Physical function (at study completion) WOMAC (self administered health status measure) from 0 to 68; lower scores mean better function
no estimate extracted4 studies · 310 participantsLow
Downgraded: risk of bias, imprecision
Quality of life (at study completion) EuroQol (VAS) from 0 to 200 mm; higher score means better function
no estimate extracted1 study · 214 participantsVery low
Downgraded: risk of bias, imprecision
Adverse effects (related to the exercise programs)
Peto OR 1.72 [0.51, 5.81]4 studies · 364 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency
Severe adverse events or withdrawals (due to adverse events) ‐ not reported
no estimate extractedNRNo studies

Subgroup analysis: Exercise duration versus resistance in people with knee or hip osteoarthritis

Population: People with knee or hip osteoarthritis
4 questions
OutcomeEffectEvidenceStatus / GRADE
Pain ‐ duration exercise WOMAC (VAS or Likert) from 0 to 20
Subgroup analysis: Exercise duration vs resistance
no estimate extracted2 studies · 200 participantsVery low
Downgraded: risk of bias, imprecision
Pain ‐ resistance exercise WOMAC (VAS or Likert) from 0 to 20
Subgroup analysis: Exercise duration vs resistance
no estimate extracted2 studies · 113 participantsVery low
Downgraded: risk of bias, imprecision
Function ‐ duration exercise WOMAC from 0 to 68
Subgroup analysis: Exercise duration vs resistance
no estimate extracted2 studies · 200 participantsVery low
Downgraded: risk of bias, imprecision
Function ‐ resistance exercise WOMAC from 0 to 68
Subgroup analysis: Exercise duration vs resistance
no estimate extracted2 studies · 113 participantsLow
Downgraded: risk of bias, imprecision