Cochrane · systematic review · CD004020
Braces and orthoses for treating osteoarthritis of the knee
Duivenvoorden, T, Brouwer, RW, van Raaij, TM, et al. · Cochrane Database of Systematic Reviews · 2015 · Cochrane Library
MusculoskeletalAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
28
current version
GRADE rated
17
No studies
11
Included studies
NR
No studies 11 · 39.3%Ungraded 0 · 0%Very low 0 · 0%Low 10 · 35.7%Moderate 7 · 25%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Braces and orthoses for varus medial osteoarthritis of the knee
Population: patients with varus medial osteoarthritis of the knee
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Pain on walking (VAS) Scale from 0 to 10 | no estimate extracted | 1 study · 115 participants | Low Downgraded: risk of bias |
Knee function (HSS) Scale from 0 to 100 | no estimate extracted | 1 study · 110 participants | Low Downgraded: risk of bias |
Quality of life (EQ‐5D) Scale from 0 to 100 | no estimate extracted | 1 study · 117 participants | Low Downgraded: risk of bias |
Total number of adverse events (withdrawals due to lack of effect)c | RR 1.63 [0.94, 2.82] | 1 study · 117 participants | Low Downgraded: risk of bias |
Pain on walking (NRS) Scale from 0 to 10 | no estimate extracted | 2 studies · 224 participants | Moderate Downgraded: risk of bias |
Physical function (WOMAC) ‐ 12 months Scale from 0 to 100 | no estimate extracted | 3 studies · 358 participants | Moderate Downgraded: risk of bias |
Health‐related quality of life (HRQoL) Scale from 0 to 1.0 | no estimate extracted | 1 study · 179 participants | Moderate Downgraded: risk of bias |
Valgus knee brace compared with no brace for varus medial osteoarthritis of the knee
Population: patients with varus medial osteoarthritis of the knee
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Pain VAS: scale from 0 to 10 Valgus knee brace vs no brace | no estimate extracted | 1 study · 115 participants | Low Downgraded: risk of bias |
Stiffness Valgus knee brace vs no brace | no estimate extracted | NR | No studies |
Function HSS: scale from 0 to 100 Valgus knee brace vs no brace | no estimate extracted | 1 study · 110 participants | Low Downgraded: risk of bias |
Health‐related quality of life EQ‐5S: scale from 0 to 100 Valgus knee brace vs no brace | no estimate extracted | 1 study · 117 participants | Low Downgraded: risk of bias |
Treatment failure Valgus knee brace vs no brace | no estimate extracted | NR | No studies |
Serious adverse events Valgus knee brace vs no brace | no estimate extracted | NR | No studies |
Total number of adverse events (withdrawals due to lack of effect)d Valgus knee brace vs no brace | no estimate extracted | 1 study · 117 participants | Low Downgraded: risk of bias |
Lateral wedge insole compared with neutral insole for varus medial osteoarthritis of the knee
Population: patients with varus medial osteoarthritis of the knee
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Pain NRS: scale from 0 to 10 Lateral wedge insole vs neutral insole | no estimate extracted | 2 studies · 224 participants | Moderate Downgraded: risk of bias |
Stiffness WOMAC: scale from 0 to 100 Lateral wedge insole vs neutral insole | no estimate extracted | 3 studies · 358 participants | Moderate Downgraded: risk of bias |
Function WOMAC: scale from 0 to 100 Lateral wedge insole vs neutral insole | no estimate extracted | 3 studies · 358 participants | Moderate Downgraded: risk of bias |
Health‐related quality of life HRQoL: scale from 0 to 1.0 Lateral wedge insole vs neutral insole | no estimate extracted | 1 study · 179 participants | Moderate Downgraded: risk of bias, imprecision |
Treatment failure Lateral wedge insole vs neutral insole | no estimate extracted | NR | No studies |
Serious adverse events Lateral wedge insole vs neutral insole | no estimate extracted | NR | No studies |
Total number of adverse events Lateral wedge insole vs neutral insole | no estimate extracted | NR | No studies |
Valgus knee brace compared with lateral wedge insole for varus medial osteoarthritis of the knee
Population: patients with varus medial osteoarthritis of the knee
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Pain VAS: scale from 0 to 10 Valgus knee brace vs lateral wedge insole | no estimate extracted | 1 study · 91 participants | Low Downgraded: imprecision |
Stiffness Valgus knee brace vs lateral wedge insole | no estimate extracted | NR | No studies |
Function WOMAC: scale from 0 to 100 Valgus knee brace vs lateral wedge insole | no estimate extracted | 1 study · 91 participants | Low Downgraded: imprecision |
Health‐related quality of life Valgus knee brace vs lateral wedge insole | no estimate extracted | NR | No studies |
Treatment failure Valgus knee brace vs lateral wedge insole | no estimate extracted | NR | No studies |
Serious adverse events Valgus knee brace vs lateral wedge insole | no estimate extracted | NR | No studies |
Total number of adverse events Valgus knee brace vs lateral wedge insole | no estimate extracted | NR | No studies |