Cochrane Review Group

Musculoskeletal

143 systematic reviews in Musculoskeletal ask 1,956 questions. 28.4% have no studies to answer them, 13% rest on very low certainty evidence and 24.8% reach moderate or high certainty.

Reviews
143
Questions
1,956
current versions
No studies
28.4%
Moderate or high
24.8%
No studies 555 · 28.4%Ungraded 107 · 5.5%Very low 255 · 13%Low 555 · 28.4%Moderate 357 · 18.3%High 127 · 6.5%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
Methotrexate vs placebo
Outcomes(time frame of absolute effects) · children and young people with JIA
Methotrexate for juvenile idiopathic arthritis (2024) · Cochrane
no estimate extractedNRNo studies
Oral methotrexate plus intra‐articular glucocorticoid vs intra‐articular glucocorticoid alone
Treatment responsea · children and young people with JIA
Methotrexate for juvenile idiopathic arthritis (2024) · Cochrane
no estimate extractedNRNo studies
Oral methotrexate plus intra‐articular glucocorticoid vs intra‐articular glucocorticoid alone
Function · children and young people with JIA
Methotrexate for juvenile idiopathic arthritis (2024) · Cochrane
no estimate extractedNRNo studies
Oral methotrexate plus intra‐articular glucocorticoid vs intra‐articular glucocorticoid alone
Pain · children and young people with JIA
Methotrexate for juvenile idiopathic arthritis (2024) · Cochrane
no estimate extractedNRNo studies
Oral methotrexate plus intra‐articular glucocorticoid vs intra‐articular glucocorticoid alone
Participant global assessment of well‐being · children and young people with JIA
Methotrexate for juvenile idiopathic arthritis (2024) · Cochrane
no estimate extractedNRNo studies
Oral methotrexate plus intra‐articular glucocorticoid vs intra‐articular glucocorticoid alone
Serious adverse events(12 months) · children and young people with JIA
Methotrexate for juvenile idiopathic arthritis (2024) · Cochrane
no estimate extractedNRVery low
Methotrexate vs alternative disease‐modifying antirheumatic drugs
Outcomes(time frame of absolute effects) · children and young people with JIA
Methotrexate for juvenile idiopathic arthritis (2024) · Cochrane
no estimate extractedNRNo studies
Methotrexate vs alternative disease‐modifying antirheumatic drugs
Sustained clinically inactive diseasec · children and young people with JIA
Methotrexate for juvenile idiopathic arthritis (2024) · Cochrane
no estimate extractedNRNo studies
Methotrexate vs alternative disease‐modifying antirheumatic drugs
Pain · children and young people with JIA
Methotrexate for juvenile idiopathic arthritis (2024) · Cochrane
no estimate extractedNRNo studies
Methotrexate vs placebo
Sustained clinically inactive diseasec · children and young people with JIA
Methotrexate for juvenile idiopathic arthritis (2024) · Cochrane
no estimate extractedNRNo studies
Methotrexate vs placebo
Function · children and young people with JIA
Methotrexate for juvenile idiopathic arthritis (2024) · Cochrane
no estimate extractedNRNo studies
Oral methotrexate plus intra‐articular glucocorticoid vs intra‐articular glucocorticoid alone
Outcomes(time frame of absolute effects) · children and young people with JIA
Methotrexate for juvenile idiopathic arthritis (2024) · Cochrane
no estimate extractedNRNo studies

Reviews 143

Non‐steroidal anti‐inflammatory drugs (NSAIDs) for treating lateral elbow pain in adults

Pattanittum, P, Turner, T, et al. · Cochrane Database of Systematic Reviews · 2013
CochraneSoF table
18 questions

Methotrexate for ankylosing spondylitis

Chen, J, Veras, MMS, et al. · Cochrane Database of Systematic Reviews · 2013
CochraneSoF table
7 questions

Etanercept for the treatment of rheumatoid arthritis

Lethaby, A, Lopez‐Olivo, MA, et al. · Cochrane Database of Systematic Reviews · 2013
CochraneSoF table
25 questions

Retention versus sacrifice of the posterior cruciate ligament in total knee arthroplasty for treating osteoarthritis

Verra, WC, van den Boom, LGH, et al. · Cochrane Database of Systematic Reviews · 2013
CochraneSoF table
21 questions

Acupuncture for treating fibromyalgia

Deare, JC, Zheng, Z, et al. · Cochrane Database of Systematic Reviews · 2013
CochraneSoF table
35 questions

Non‐pharmacological interventions for fatigue in rheumatoid arthritis

Cramp, F, Hewlett, S, et al. · Cochrane Database of Systematic Reviews · 2013
CochraneSoF table
7 questions

Lifestyle interventions for chronic gout

Moi, JHY, Sriranganathan, MK, et al. · Cochrane Database of Systematic Reviews · 2013
CochraneSoF table
7 questions

Lifestyle interventions for acute gout

Moi, JHY, Sriranganathan, MK, et al. · Cochrane Database of Systematic Reviews · 2013
CochraneSoF table
7 questions

Topical herbal therapies for treating osteoarthritis

Cameron, M, Chrubasik, S · Cochrane Database of Systematic Reviews · 2013
CochraneSoF table
19 questions

Resistance exercise training for fibromyalgia

Busch, AJ, Webber, SC, et al. · Cochrane Database of Systematic Reviews · 2013
CochraneSoF table
19 questions

Cemented, cementless or hybrid fixation options in total knee arthroplasty for osteoarthritis and other non‐traumatic diseases

Nakama, GY, Peccin, MS, et al. · Cochrane Database of Systematic Reviews · 2012
CochraneSoF table
7 questions

Doxycycline for osteoarthritis of the knee or hip

da Costa, BR, Nüesch, E, et al. · Cochrane Database of Systematic Reviews · 2012
CochraneSoF table
6 questions

Febuxostat for treating chronic gout

Tayar, JH, Lopez‐Olivo, MA, et al. · Cochrane Database of Systematic Reviews · 2012
CochraneSoF table
42 questions

Neuromodulators for pain management in rheumatoid arthritis

Richards, BL, Whittle, SL, et al. · Cochrane Database of Systematic Reviews · 2012
CochraneSoF table
9 questions

Muscle relaxants for pain management in rheumatoid arthritis

Richards, BL, Whittle, SL, et al. · Cochrane Database of Systematic Reviews · 2012
CochraneSoF table
6 questions

Monoamine oxidase inhibitors (MAOIs) for fibromyalgia syndrome

Tort, S, Urrútia, G, et al. · Cochrane Database of Systematic Reviews · 2012
CochraneSoF table
7 questions

Exercise for preventing and treating osteoporosis in postmenopausal women

Howe, TE, Shea, B, et al. · Cochrane Database of Systematic Reviews · 2011
CochraneSoF table
7 questions

Herbal therapy for treating rheumatoid arthritis

Cameron, M, Gagnier, JJ, et al. · Cochrane Database of Systematic Reviews · 2011
CochraneSoF table
12 questions

Opioid therapy for treating rheumatoid arthritis pain

Whittle, SL, Richards, BL, et al. · Cochrane Database of Systematic Reviews · 2011
CochraneSoF table
6 questions

Surgery for lateral elbow pain

Buchbinder, R, Johnston, RV, et al. · Cochrane Database of Systematic Reviews · 2011
CochraneSoF table
13 questions

Safety of non‐steroidal anti‐inflammatory drugs, including aspirin and paracetamol (acetaminophen) in people receiving methotrexate for inflammatory arthritis (rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis, other spondyloarthritis)

Colebatch, AN, Marks, JL, et al. · Cochrane Database of Systematic Reviews · 2011
CochraneSoF table
6 questions

Antidepressants for pain management in rheumatoid arthritis

Richards, BL, Whittle, SL, et al. · Cochrane Database of Systematic Reviews · 2011
CochraneSoF table
6 questions

Acupuncture for peripheral joint osteoarthritis

Manheimer, E, Cheng, K, et al. · Cochrane Database of Systematic Reviews · 2010
CochraneSoF table
12 questions

Therapeutic ultrasound for osteoarthritis of the knee or hip

Rutjes, AWS, Nüesch, E, et al. · Cochrane Database of Systematic Reviews · 2010
CochraneSoF table
5 questions

Surgical interventions for the rheumatoid shoulder

Christie, A, Dagfinrud, H, et al. · Cochrane Database of Systematic Reviews · 2010
CochraneSoF table
7 questions