Cochrane · systematic review · CD010039

Lifestyle interventions for chronic gout

Moi, JHY, Sriranganathan, MK, Edwards, CJ, et al. · Cochrane Database of Systematic Reviews · 2013 · Cochrane Library

MusculoskeletalAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
5
No studies
2
Included studies
NR
No studies 2 · 28.6%Ungraded 0 · 0%Very low 0 · 0%Low 5 · 71.4%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Skim milk enriched with GMP/G600 compared to skim milk & lactose powder for chronic gout

Population: patients with chronic gout
7 questions
OutcomeEffectEvidenceStatus / GRADE
Acute gout attack frequency participant self‐report using gout flare diary
Skim milk enriched with GMP/G600 vs skim milk & lactose powder
no estimate extracted1 study · 120 participantsLow
Downgraded: risk of bias
Participant withdrawals due to adverse events participant and study investigator reported
Skim milk enriched with GMP/G600 vs skim milk & lactose powder
RR 1.27 [0.53, 3.03]1 study · 120 participantsLow
Downgraded: risk of bias
Joint pain reduction 10‐point Likert scale (0 is no pain)
Skim milk enriched with GMP/G600 vs skim milk & lactose powder
no estimate extracted1 study · 120 participantsLow
Downgraded: risk of bias
Tophus regression ‐ not measured
Skim milk enriched with GMP/G600 vs skim milk & lactose powder
no estimate extractedNRNo studies
Physical function HAQ‐II. Scale from: 0 to 3; 0 is minimal loss of function.
Skim milk enriched with GMP/G600 vs skim milk & lactose powder
no estimate extracted1 study · 120 participantsLow
Downgraded: risk of bias
Serum urate normalisation4 ‐ not reported
Skim milk enriched with GMP/G600 vs skim milk & lactose powder
no estimate extractedNRNo studies
Serious adverse events participant and study investigator reported
Skim milk enriched with GMP/G600 vs skim milk & lactose powder
RR 1.33 [0.23, 7.66]1 study · 120 participantsLow
Downgraded: risk of bias