Cochrane · systematic review · CD003686
Non‐steroidal anti‐inflammatory drugs (NSAIDs) for treating lateral elbow pain in adults
Pattanittum, P, Turner, T, Green, S, et al. · Cochrane Database of Systematic Reviews · 2013 · Cochrane Library
MusculoskeletalAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
18
current version
GRADE rated
10
No studies
7
Included studies
NR
No studies 7 · 38.9%Ungraded 1 · 5.6%Very low 4 · 22.2%Low 6 · 33.3%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Topical NSAIDs compared to placebo for treating lateral elbow pain in adults
Population: Adults with lateral elbow pain
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Pain 0 to 10 visual analogue scale (0 = no pain) Topical NSAIDs vs placebo | no estimate extracted | 3 studies · 153 participants | Very low Downgraded: risk of bias, imprecision |
Treatment success Fair, good or excellent effectiveness Topical NSAIDs vs placebo | RR 1.49 [1.04, 2.14] | 1 study · 85 participants | Low Downgraded: imprecision |
Function/disability Topical NSAIDs vs placebo | no estimate extracted | NR | No studies |
Quality of life Topical NSAIDs vs placebo | no estimate extracted | NR | No studies |
Withdrawal due to adverse events Topical NSAIDs vs placebo | no estimate extracted | 4 studies · 185 participants | Low Downgraded: risk of bias, imprecision |
Adverse events Topical NSAIDs vs placebo | RR 1.55 [0.2, 12.14] | 3 studies · 153 participants | Low Downgraded: risk of bias, imprecision |
Oral NSAIDs compared to placebo for treating lateral elbow pain in adults
Population: adults with lateral elbow pain
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Pain 0 to 100 visual analogue scale and 10‐point Likert scale (lower score = less pain) Oral NSAIDs vs placebo | no estimate extracted | 2 studies · 292 participants | Very low Downgraded: imprecision, inconsistency |
Treatment success Fair, good or excellent effectiveness Oral NSAIDs vs placebo | RR 1.17 [0.82, 1.67] | 1 study · 111 participants | Low Downgraded: imprecision |
Quality of life Oral NSAIDs vs placebo | no estimate extracted | NR | No studies |
Function/disability 0 to 100 visual analogue scale (higher score = less disability) and 10‐point Likert scale (lower score = less disability) Oral NSAIDs vs placebo | no estimate extracted | 2 studies · 292 participants | Low Downgraded: imprecision |
Withdrawal due to adverse events Oral NSAIDs vs placebo | no estimate extracted | NR | No studies |
Adverse events Oral NSAIDs vs placebo | no estimate extracted | 2 studies · 292 participants | Ungraded |
Oral NSAIDs compared to glucocorticoid injection for treating lateral elbow pain in adults
Population: Adults with lateral elbow pain
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Pain 9‐ and 10‐point Likert scales (lower score = less pain) Oral NSAIDs vs glucocorticoid injection | no estimate extracted | 2 studies · 126 participants | Very low Downgraded: risk of bias, inconsistency |
Treatment success Fair, good or excellent effectiveness Oral NSAIDs vs glucocorticoid injection | RR 0.74 [0.43, 1.26] | 2 studies · 126 participants | Very low Downgraded: risk of bias, imprecision |
Quality of life Oral NSAIDs vs glucocorticoid injection | no estimate extracted | NR | No studies |
Function/disability 10‐point Likert scale (lower score = less disability) Oral NSAIDs vs glucocorticoid injection | no estimate extracted | 1 study · 105 participants | Low Downgraded: risk of bias |
Withdrawal due to adverse events Oral NSAIDs vs glucocorticoid injection | no estimate extracted | NR | No studies |
Adverse events Oral NSAIDs vs glucocorticoid injection | no estimate extracted | NR | No studies |