Cochrane · systematic review · CD010538
Topical herbal therapies for treating osteoarthritis
Cameron, M, Chrubasik, S · Cochrane Database of Systematic Reviews · 2013 · Cochrane Library
MusculoskeletalAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
19
current version
GRADE rated
11
No studies
8
Included studies
NR
No studies 8 · 42.1%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 11 · 57.9%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Arnica versus ibuprofen for osteoarthritis of the hand
Population: patients with osteoarthritis of the hand
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Pain VAS 0 to 100 (higher scores means worse) Arnica vs ibuprofen | no estimate extracted | 1 study · 174 participants | Moderate Downgraded: imprecision |
Function Hand algofunctional index (higher scores means worse) Arnica vs ibuprofen | no estimate extracted | 1 study · 174 participants | Moderate Downgraded: imprecision |
Adverse events Participants (n) reported events Arnica vs ibuprofen | RR 1.65 [0.72, 3.76] | 1 study · 204 participants | Moderate Downgraded: imprecision |
Adverse events Participants (n) withdrew due to adverse effects Arnica vs ibuprofen | no estimate extracted | NR | No studies |
Adverse events Participants (n) reported serious adverse events Arnica vs ibuprofen | no estimate extracted | NR | No studies |
Quality of life Arnica vs ibuprofen | no estimate extracted | NR | No studies |
Capsicum for osteoarthritis of the knee
Population: patients with osteoarthritis of the knee
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Pain VAS 0‐100 (higher means worse) | no estimate extracted | 1 study · 99 participants | Moderate Downgraded: imprecision |
Function WOMAC 0‐4 (Function; higher means worse) | no estimate extracted | 1 study · 99 participants | Moderate Downgraded: imprecision |
Function WOMAC 0‐4 (Overall; higher means worse) | no estimate extracted | 1 study · 99 participants | Moderate Downgraded: imprecision |
Adverse events Event episodes (n) reported | Rate Ratio 4.12 [3.3, 5.17] | 1 study · 676 participants | Moderate Downgraded: imprecision |
Adverse events Participants (n) withdrew due to adverse effects | no estimate extracted | NR | No studies |
Adverse events Participants (n) reported serious adverse events | no estimate extracted | NR | No studies |
Quality of Life | no estimate extracted | NR | No studies |
Comfrey for osteoarthritis of the knee
Population: patients with osteoarthritis of the knee
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Pain VAS 0‐100 (higher means worse) | no estimate extracted | 1 study · 220 participants | Moderate |
Function: change from baseline WOMAC VAS (Function; higher means worse) | no estimate extracted | 1 study · 220 participants | Moderate |
Adverse events Participants (n) reported adverse events | RR 0.47 [0.2, 1.1] | 1 study · 220 participants | Moderate |
Adverse events Participants (n) withdrew due to adverse effects | no estimate extracted | NR | No studies |
Adverse events Participants (n) reported serious adverse events | no estimate extracted | NR | No studies |
Quality of life SF‐36 4 | no estimate extracted | 1 study · 220 participants | Moderate |