Cochrane · systematic review · CD005467
Chinese herbal medicines for treating osteoporosis
Liu, Y, Liu, JP, Xia, Y · Cochrane Database of Systematic Reviews · 2014 · Cochrane Library
MusculoskeletalAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
28
current version
GRADE rated
16
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 12 · 42.9%Very low 6 · 21.4%Low 10 · 35.7%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Chinese herbal medicines versus placebo for osteoporosis
Population: patients with osteoporosis
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
New fractures (Kanggusong capsule versus placebo) Chinese herbal medicines vs placebo | RR 0.05 [0, 0.85] | 1 study · 104 participants | Very low Downgraded: risk of bias, imprecision |
Quality of life Chinese herbal medicines vs placebo | no estimate extracted | 0 studies · 0 participants | Ungraded |
Death Chinese herbal medicines vs placebo | no estimate extracted | 0 studies · 0 participants | Ungraded |
Serious adverse events Chinese herbal medicines vs placebo | no estimate extracted | 0 studies · 0 participants | Ungraded |
BMD of lumbar spine (Kanggusong capsule versus placebo) Chinese herbal medicines vs placebo | no estimate extracted | 1 study · 140 participants | Low Downgraded: risk of bias |
BMD of ulna (Bushen Yigu soft extract versus placebo) Chinese herbal medicines vs placebo | no estimate extracted | 1 study · 59 participants | Low Downgraded: risk of bias |
BMD of radius (Bushen Yigu soft extract versus placebo) Chinese herbal medicines vs placebo | no estimate extracted | 1 study · 59 participants | Low Downgraded: risk of bias |
Chinese herbal medicines versus no intervention for osteoporosis
Population: patients with osteoporosis
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
New fractures Chinese herbal medicines vs no intervention | no estimate extracted | 0 studies · 0 participants | Ungraded |
Quality of life Chinese herbal medicines vs no intervention | no estimate extracted | 0 studies · 0 participants | Ungraded |
Death Chinese herbal medicines vs no intervention | no estimate extracted | 0 studies · 0 participants | Ungraded |
Serious adverse events Chinese herbal medicines vs no intervention | no estimate extracted | 0 studies · 0 participants | Ungraded |
BMD of lumbar spine (Bushen Shengsui principle versus no intervention) Chinese herbal medicines vs no intervention | no estimate extracted | 1 study · 61 participants | Low Downgraded: risk of bias |
BMD of femoral neck (Shigu yin versus no intervention) Chinese herbal medicines vs no intervention | no estimate extracted | 1 study · 80 participants | Low Downgraded: risk of bias |
BMD of femoral neck (Shengu capsule versus no intervention) Chinese herbal medicines vs no intervention | no estimate extracted | 1 study · 34 participants | Low Downgraded: risk of bias |
Chinese herbal medicines versus western medicine for osteoporosis
Population: patients with osteoporosis
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
New fractures (Kanggusong granule versus calcium and vitamin D) Chinese herbal medicines vs western medicine | no estimate extracted | 1 study · 71 participants | Very low Downgraded: risk of bias |
Quality of life Chinese herbal medicines vs western medicine | no estimate extracted | 0 studies · 0 participants | Ungraded |
Death Chinese herbal medicines vs western medicine | no estimate extracted | 0 studies · 0 participants | Ungraded |
Serious adverse events Chinese herbal medicines vs western medicine | no estimate extracted | 0 studies · 0 participants | Ungraded |
BMD of lumbar spine (Bushenjianpi Zhuangguyin versus Caltrate and calcitonin) Chinese herbal medicines vs western medicine | no estimate extracted | 1 study · 100 participants | Low Downgraded: risk of bias |
BMD of lumbar spine (Liuwei Dihuang pills versus calcium and vitamin D) Chinese herbal medicines vs western medicine | no estimate extracted | 1 study · 71 participants | Low Downgraded: risk of bias |
BMD of femoral neck (Kanggusong granule versus calcium and vitamin D) Chinese herbal medicines vs western medicine | no estimate extracted | 1 study · 71 participants | Low Downgraded: risk of bias |
Chinese herbal medicines plus western medicine versus western medicine for osteoporosis
Population: patients with osteoporosis
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
New fractures (Yigu capsule plus calcium versus placebo plus calcium) Chinese herbal medicines plus western medicine vs western medicine | RR 0.06 [0, 1] | 1 study · 140 participants | Very low Downgraded: risk of bias |
New fractures (Xianlinggubao capsule (low‐dose) plus calcium and vitamin D versus placebo plus calcium and vitamin D) Chinese herbal medicines plus western medicine vs western medicine | RR 0.33 [0.01, 8.02] | 1 study · 120 participants | Very low Downgraded: risk of bias |
New fractures (Bushen Zhuanggu granules plus calcium and vitamin D versus placebo granules plus calcium and vitamin D) Chinese herbal medicines plus western medicine vs western medicine | RR 0.44 [0.13, 1.43] | 1 study · 155 participants | Very low Downgraded: risk of bias |
New fractures (Kanggusong soup plus calcium and vitamin D versus calcium and vitamin D) Chinese herbal medicines plus western medicine vs western medicine | RR 0.22 [0.01, 5.34] | 1 study · 75 participants | Very low Downgraded: risk of bias |
Quality of life (Bushenhuoxue therapy plus calcium carbonate tablets and alfacalcidol versus calcium carbonate tablets and alfacalcidol) Chinese herbal medicines plus western medicine vs western medicine | no estimate extracted | 1 study · 80 participants | Low Downgraded: risk of bias |
Death Chinese herbal medicines plus western medicine vs western medicine | no estimate extracted | 0 studies · 0 participants | Ungraded |
Serious adverse events Chinese herbal medicines plus western medicine vs western medicine | no estimate extracted | 0 studies · 0 participants | Ungraded |