Cochrane Review Group

Common Mental Disorders

117 systematic reviews in Common Mental Disorders ask 2,206 questions. 17.5% have no studies to answer them, 28.8% rest on very low certainty evidence and 22.9% reach moderate or high certainty.

Reviews
117
Questions
2,206
current versions
No studies
17.5%
Moderate or high
22.9%
No studies 387 · 17.5%Ungraded 111 · 5%Very low 635 · 28.8%Low 568 · 25.7%Moderate 449 · 20.4%High 56 · 2.5%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
Any psychological therapy vs any non‐therapy comparator: end‐of‐intervention and short‐term follow‐up
Depressive symptomatology (lower = less depressive symptomatology): end‐of‐intervention · older people with depression
Psychological therapies for depression in older adults residing in long‐term care settings (2024) · Cochrane
no estimate extracted18 studies · 644 participantsVery low
Any psychological therapy vs any non‐therapy comparator: end‐of‐intervention and short‐term follow‐up
Treatment non‐acceptability (higher = greater non‐acceptability): end‐of‐intervention · older people with depression
Psychological therapies for depression in older adults residing in long‐term care settings (2024) · Cochrane
no estimate extracted5 studies · 313 participantsVery low
Any psychological therapy vs any non‐therapy comparator: end‐of‐intervention and short‐term follow‐up
Depression remission (presence or absence of MDD):end‐of‐intervention · older people with depression
Psychological therapies for depression in older adults residing in long‐term care settings (2024) · Cochrane
no estimate extracted1 study · 82 participantsVery low
Any psychological therapy vs any non‐therapy comparator: end‐of‐intervention and short‐term follow‐up
Quality of life or psychological well‐being (higher = higher quality of life or psychological well‐being): end‐of‐intervention · older people with depression
Psychological therapies for depression in older adults residing in long‐term care settings (2024) · Cochrane
no estimate extracted6 studies · 195 participantsVery low
Any psychological therapy vs any non‐therapy comparator: end‐of‐intervention and short‐term follow‐up
Anxious symptomatology (lower = less anxious symptomatology): end‐of‐intervention · older people with depression
Psychological therapies for depression in older adults residing in long‐term care settings (2024) · Cochrane
no estimate extracted2 studies · 115 participantsVery low
Escitalopram vs placebo
PTSD severity at 3 months · adults experiencing acute traumatic stress symptoms
Early pharmacological interventions for prevention of post‐traumatic stress disorder (PTSD) in individuals… (2024) · Cochrane
no estimate extracted1 study · 23 participantsVery low
Hydrocortisone vs placebo
Quality of life at 3 months · adults experiencing acute traumatic stress symptoms
Early pharmacological interventions for prevention of post‐traumatic stress disorder (PTSD) in individuals… (2024) · Cochrane
no estimate extracted1 study · 43 participantsVery low
Escitalopram vs placebo
Dropouts due to adverse events at 3 months · adults experiencing acute traumatic stress symptoms
Early pharmacological interventions for prevention of post‐traumatic stress disorder (PTSD) in individuals… (2024) · Cochrane
no estimate extracted1 study · 31 participantsVery low
Escitalopram vs placebo
PTSD rate at 3 months · adults experiencing acute traumatic stress symptoms
Early pharmacological interventions for prevention of post‐traumatic stress disorder (PTSD) in individuals… (2024) · Cochrane
RR 0.59 [0.03, 13.08]1 study · 23 participantsVery low
Escitalopram vs placebo
Functional disability at 3 months ‐ not measured · adults experiencing acute traumatic stress symptoms
Early pharmacological interventions for prevention of post‐traumatic stress disorder (PTSD) in individuals… (2024) · Cochrane
no estimate extractedNRNo studies
Escitalopram vs placebo
Quality of life at 3 months ‐ not measured · adults experiencing acute traumatic stress symptoms
Early pharmacological interventions for prevention of post‐traumatic stress disorder (PTSD) in individuals… (2024) · Cochrane
no estimate extractedNRNo studies
Hydrocortisone vs placebo
PTSD severity at 3 months · adults experiencing acute traumatic stress symptoms
Early pharmacological interventions for prevention of post‐traumatic stress disorder (PTSD) in individuals… (2024) · Cochrane
no estimate extracted3 studies · 136 participantsVery low

Reviews 117

Psychological therapies for post‐traumatic stress disorder and comorbid substance use disorder

Roberts, NP, Roberts, PA, et al. · Cochrane Database of Systematic Reviews · 2016
CochraneSoF table
15 questions

Psychological therapies for panic disorder with or without agoraphobia in adults: a network meta‐analysis

Pompoli, A, Furukawa, TA, et al. · Cochrane Database of Systematic Reviews · 2016
CochraneSoF table
20 questions

Routine use of patient reported outcome measures (PROMs) for improving treatment of common mental health disorders in adults

Kendrick, T, El‐Gohary, M, et al. · Cochrane Database of Systematic Reviews · 2016
CochraneSoF table
9 questions

Psychological therapies versus pharmacological interventions for panic disorder with or without agoraphobia in adults

Imai, H, Tajika, A, et al. · Cochrane Database of Systematic Reviews · 2016
CochraneSoF table
25 questions

S‐adenosyl methionine (SAMe) for depression in adults

Galizia, I, Oldani, L, et al. · Cochrane Database of Systematic Reviews · 2016
CochraneSoF table
20 questions

Therapist‐supported Internet cognitive behavioural therapy for anxiety disorders in adults

Olthuis, JV, Watt, MC, et al. · Cochrane Database of Systematic Reviews · 2016
CochraneSoF table
18 questions

Antidepressants and benzodiazepines for panic disorder in adults

Bighelli, I, Trespidi, C, et al. · Cochrane Database of Systematic Reviews · 2016
CochraneSoF table
42 questions

Psychosocial interventions for self‐harm in adults

Hawton, K, Witt, KG, et al. · Cochrane Database of Systematic Reviews · 2016
CochraneSoF table
46 questions

Psychological therapies for children and adolescents exposed to trauma

Gillies, D, Maiocchi, L, et al. · Cochrane Database of Systematic Reviews · 2016
CochraneSoF table
4 questions

Individual psychological therapy in the outpatient treatment of adults with anorexia nervosa

Hay, PJ, Claudino, AM, et al. · Cochrane Database of Systematic Reviews · 2015
CochraneSoF table
15 questions

Cognitive behavioural therapy for anxiety disorders in children and adolescents

James, AC, James, G, et al. · Cochrane Database of Systematic Reviews · 2015
CochraneSoF table
9 questions

Debriefing interventions for the prevention of psychological trauma in women following childbirth

Bastos, MH, Furuta, M, et al. · Cochrane Database of Systematic Reviews · 2015
CochraneSoF table
7 questions

Pharmacotherapy for anxiety and comorbid alcohol use disorders

Ipser, JC, Wilson, D, et al. · Cochrane Database of Systematic Reviews · 2015
CochraneSoF table
7 questions

Augmentation of cognitive and behavioural therapies (CBT) with d‐cycloserine for anxiety and related disorders

Ori, R, Amos, T, et al. · Cochrane Database of Systematic Reviews · 2015
CochraneSoF table
14 questions

Morita therapy for anxiety disorders in adults

Wu, H, Yu, D, et al. · Cochrane Database of Systematic Reviews · 2015
CochraneSoF table
14 questions

Dance movement therapy for depression

Meekums, B, Karkou, V, et al. · Cochrane Database of Systematic Reviews · 2015
CochraneSoF table
5 questions

Pharmacological interventions for self‐harm in adults

Hawton, K, Witt, KG, et al. · Cochrane Database of Systematic Reviews · 2015
CochraneSoF table
5 questions

Interventions for self‐harm in children and adolescents

Hawton, K, Witt, KG, et al. · Cochrane Database of Systematic Reviews · 2015
CochraneSoF table
11 questions

Antidepressant treatment for postnatal depression

Molyneaux, E, Howard, LM, et al. · Cochrane Database of Systematic Reviews · 2014
CochraneSoF table
2 questions

Pharmacological interventions for preventing post‐traumatic stress disorder (PTSD)

Amos, T, Stein, DJ, et al. · Cochrane Database of Systematic Reviews · 2014
CochraneSoF table
2 questions

Paroxetine versus other anti‐depressive agents for depression

Purgato, M, Papola, D, et al. · Cochrane Database of Systematic Reviews · 2014
CochraneSoF table
133 questions

Repetitive transcranial magnetic stimulation (rTMS) for panic disorder in adults

Li, H, Wang, J, et al. · Cochrane Database of Systematic Reviews · 2014
CochraneSoF table
6 questions

Psychological, social and welfare interventions for psychological health and well‐being of torture survivors

Patel, N, Kellezi, B, et al. · Cochrane Database of Systematic Reviews · 2014
CochraneSoF table
7 questions

Pharmacological interventions for somatoform disorders in adults

Kleinstäuber, M, Witthöft, M, et al. · Cochrane Database of Systematic Reviews · 2014
CochraneSoF table
35 questions

Azapirones versus placebo for panic disorder in adults

Imai, H, Tajika, A, et al. · Cochrane Database of Systematic Reviews · 2014
CochraneSoF table
5 questions