Cochrane · systematic review · CD011565

Therapist‐supported Internet cognitive behavioural therapy for anxiety disorders in adults

Olthuis, JV, Watt, MC, Bailey, K, et al. · Cochrane Database of Systematic Reviews · 2016 · Cochrane Library

Common Mental Disorders2 versionsAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
18
current version
GRADE rated
12
No studies
1
Included studies
NR
No studies 1 · 5.6%Ungraded 5 · 27.8%Very low 4 · 22.2%Low 7 · 38.9%Moderate 1 · 5.6%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Show all 2 versions

Therapist‐supported ICBT compared to waiting list, attention, information, or online discussion group only control for anxiety disorders in adults

Population: patients with anxiety disorders
6 questions
OutcomeEffectEvidenceStatus / GRADE
Clinically important improvement in anxiety at post‐treatment Indexed by a standardized interview or clinically accepted measure cut‐off score1
Therapist‐supported ICBT vs waiting list, attention, information, or online discussion group only control
RR 3.75 [2.51, 5.6]12 studies · 866 participantsLow
Downgraded: risk of bias, inconsistency, publication bias
Disorder‐specific anxiety symptom severity at post‐treatment Indexed by a range of disorder‐specific self‐report measures
Therapist‐supported ICBT vs waiting list, attention, information, or online discussion group only control
no estimate extracted28 studies · 2147 participantsLow
Downgraded: risk of bias, inconsistency
General anxiety symptom severity at post‐treatment Indexed by a range of measures of anxiety symptoms in general
Therapist‐supported ICBT vs waiting list, attention, information, or online discussion group only control
no estimate extracted19 studies · 1496 participantsLow
Downgraded: risk of bias, inconsistency
Quality of life at post‐treatment Indexed by self‐report measures of quality of life or functional disability
Therapist‐supported ICBT vs waiting list, attention, information, or online discussion group only control
no estimate extracted23 studies · 1639 participantsModerate
Downgraded: risk of bias
Adverse events at post‐treatment not reported
Therapist‐supported ICBT vs waiting list, attention, information, or online discussion group only control
no estimate extracted0 studies · 0 participantsUngraded
Participant satisfaction Indexed by a mix of qualitative and quantitative self‐report measures
Therapist‐supported ICBT vs waiting list, attention, information, or online discussion group only control
no estimate extracted0 studies · 13 participantsUngraded

Therapist‐supported ICBT compared to unguided CBT for anxiety disorders in adults

Population: patients with anxiety disorders
6 questions
OutcomeEffectEvidenceStatus / GRADE
Clinically important improvement in anxiety at post‐treatment Indexed by a standardized interview or clinically accepted measure cut‐off score1
Therapist‐supported ICBT vs unguided CBT
no estimate extracted1 study · 54 participantsVery low
Downgraded: risk of bias, imprecision
Disorder‐specific anxiety symptom severity at post‐treatment Indexed by a range of disorder‐specific self‐report measures
Therapist‐supported ICBT vs unguided CBT
no estimate extracted5 studies · 312 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency
General anxiety symptom severity at post‐treatment Indexed by a range of measures of anxiety symptoms in general
Therapist‐supported ICBT vs unguided CBT
no estimate extracted2 studies · 138 participantsVery low
Downgraded: risk of bias, imprecision
Quality of life at post‐treatment Indexed by self‐report measures of quality of life or functional disability
Therapist‐supported ICBT vs unguided CBT
no estimate extracted3 studies · 199 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency
Adverse events at post‐treatment not reported
Therapist‐supported ICBT vs unguided CBT
no estimate extracted0 studies · 0 participantsUngraded
Participant satisfaction Indexed by a mix of qualitative and quantitative self‐report measures
Therapist‐supported ICBT vs unguided CBT
no estimate extracted0 studies · 2 participantsUngraded

Therapist‐supported ICBT compared to face‐to‐face CBT for anxiety disorders in adults

Population: adults with anxiety disorders
6 questions
OutcomeEffectEvidenceStatus / GRADE
Clinically important improvement in anxiety at post‐treatment Indexed by a standardized interview or clinically accepted measure cut‐off score1
Therapist‐supported ICBT vs face‐to‐face CBT
RR 1.09 [0.89, 1.34]4 studies · 365 participantsLow
Downgraded: risk of bias, imprecision, inconsistency
Disorder‐specific anxiety symptom severity at post‐treatment Indexed by a range of disorder‐specific self‐report measures
Therapist‐supported ICBT vs face‐to‐face CBT
no estimate extracted7 studies · 450 participantsLow
Downgraded: risk of bias, imprecision, inconsistency
General anxiety symptom severity at post‐treatment Indexed by a range of measures of anxiety symptoms in general
Therapist‐supported ICBT vs face‐to‐face CBT
no estimate extracted6 studies · 343 participantsLow
Downgraded: risk of bias, imprecision, inconsistency
Quality of life at post‐treatment Indexed by self‐report measures of quality of life or functional disability
Therapist‐supported ICBT vs face‐to‐face CBT
no estimate extracted5 studies · 392 participantsLow
Downgraded: risk of bias, imprecision, inconsistency
Adverse events at post‐treatment ‐ not reported
Therapist‐supported ICBT vs face‐to‐face CBT
no estimate extractedNRNo studies
Participant satisfaction Indexed by a mix of qualitative and quantitative self‐report measures
Therapist‐supported ICBT vs face‐to‐face CBT
no estimate extracted0 studies · 2 participantsUngraded