Cochrane Review Group
Common Mental Disorders
117 systematic reviews in Common Mental Disorders ask 2,206 questions. 17.5% have no studies to answer them, 28.8% rest on very low certainty evidence and 22.9% reach moderate or high certainty.
Reviews
117
Questions
2,206
current versions
No studies
17.5%
Moderate or high
22.9%
No studies 387 · 17.5%Ungraded 111 · 5%Very low 635 · 28.8%Low 568 · 25.7%Moderate 449 · 20.4%High 56 · 2.5%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Thinnest evidence
All no studies and very low questions| Question | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Any psychological therapy vs any non‐therapy comparator: end‐of‐intervention and short‐term follow‐up Depressive symptomatology (lower = less depressive symptomatology): end‐of‐intervention · older people with depression Psychological therapies for depression in older adults residing in long‐term care settings (2024) · Cochrane | no estimate extracted | 18 studies · 644 participants | Very low |
Any psychological therapy vs any non‐therapy comparator: end‐of‐intervention and short‐term follow‐up Treatment non‐acceptability (higher = greater non‐acceptability): end‐of‐intervention · older people with depression Psychological therapies for depression in older adults residing in long‐term care settings (2024) · Cochrane | no estimate extracted | 5 studies · 313 participants | Very low |
Any psychological therapy vs any non‐therapy comparator: end‐of‐intervention and short‐term follow‐up Depression remission (presence or absence of MDD):end‐of‐intervention · older people with depression Psychological therapies for depression in older adults residing in long‐term care settings (2024) · Cochrane | no estimate extracted | 1 study · 82 participants | Very low |
Any psychological therapy vs any non‐therapy comparator: end‐of‐intervention and short‐term follow‐up Quality of life or psychological well‐being (higher = higher quality of life or psychological well‐being): end‐of‐intervention · older people with depression Psychological therapies for depression in older adults residing in long‐term care settings (2024) · Cochrane | no estimate extracted | 6 studies · 195 participants | Very low |
Any psychological therapy vs any non‐therapy comparator: end‐of‐intervention and short‐term follow‐up Anxious symptomatology (lower = less anxious symptomatology): end‐of‐intervention · older people with depression Psychological therapies for depression in older adults residing in long‐term care settings (2024) · Cochrane | no estimate extracted | 2 studies · 115 participants | Very low |
Escitalopram vs placebo PTSD severity at 3 months · adults experiencing acute traumatic stress symptoms Early pharmacological interventions for prevention of post‐traumatic stress disorder (PTSD) in individuals… (2024) · Cochrane | no estimate extracted | 1 study · 23 participants | Very low |
Hydrocortisone vs placebo Quality of life at 3 months · adults experiencing acute traumatic stress symptoms Early pharmacological interventions for prevention of post‐traumatic stress disorder (PTSD) in individuals… (2024) · Cochrane | no estimate extracted | 1 study · 43 participants | Very low |
Escitalopram vs placebo Dropouts due to adverse events at 3 months · adults experiencing acute traumatic stress symptoms Early pharmacological interventions for prevention of post‐traumatic stress disorder (PTSD) in individuals… (2024) · Cochrane | no estimate extracted | 1 study · 31 participants | Very low |
Escitalopram vs placebo PTSD rate at 3 months · adults experiencing acute traumatic stress symptoms Early pharmacological interventions for prevention of post‐traumatic stress disorder (PTSD) in individuals… (2024) · Cochrane | RR 0.59 [0.03, 13.08] | 1 study · 23 participants | Very low |
Escitalopram vs placebo Functional disability at 3 months ‐ not measured · adults experiencing acute traumatic stress symptoms Early pharmacological interventions for prevention of post‐traumatic stress disorder (PTSD) in individuals… (2024) · Cochrane | no estimate extracted | NR | No studies |
Escitalopram vs placebo Quality of life at 3 months ‐ not measured · adults experiencing acute traumatic stress symptoms Early pharmacological interventions for prevention of post‐traumatic stress disorder (PTSD) in individuals… (2024) · Cochrane | no estimate extracted | NR | No studies |
Hydrocortisone vs placebo PTSD severity at 3 months · adults experiencing acute traumatic stress symptoms Early pharmacological interventions for prevention of post‐traumatic stress disorder (PTSD) in individuals… (2024) · Cochrane | no estimate extracted | 3 studies · 136 participants | Very low |
Reviews 117
Psychological therapies for depression in older adults residing in long‐term care settings
CochraneSoF table
5 questions
Factors that influence participation in physical activity for people with bipolar disorder: a synthesis of qualitative evidence
CochraneSoF table
9 questions
Early pharmacological interventions for prevention of post‐traumatic stress disorder (PTSD) in individuals experiencing acute traumatic stress symptoms
CochraneSoF table
10 questions
Psychological and social interventions for the promotion of mental health in people living in low‐ and middle‐income countries affected by humanitarian crises
CochraneSoF table
12 questions
Specific psychological therapies versus other therapies or no treatment for severe and enduring anorexia nervosa
CochraneSoF table
3 questions
Mental Health First Aid as a tool for improving mental health and well‐being
CochraneSoF table
9 questions
Brexpiprazole versus placebo or other antidepressive agents for treating depression
CochraneSoF table
7 questions
Pharmacotherapy for post traumatic stress disorder (PTSD)
CochraneSoF table
14 questions
Pharmacological interventions for the treatment of disordered and problem gambling
CochraneSoF table
56 questions
Early pharmacological interventions for universal prevention of post‐traumatic stress disorder (PTSD)
CochraneSoF table
15 questions
Community‐based interventions for improving mental health in refugee children and adolescents in high‐income countries
CochraneSoF table
8 questions
Pharmacological treatment for psychotic depression
CochraneSoF table
48 questions
Omega‐3 fatty acids for depression in adults
CochraneSoF table
6 questions
Pharmacotherapy for trichotillomania
CochraneSoF table
30 questions
Second‐generation antidepressants for treatment of seasonal affective disorder
CochraneSoF table
12 questions
Prevention of depression in adults with long‐term physical conditions
CochraneSoF table
16 questions
Ketamine and other glutamate receptor modulators for depression in adults with bipolar disorder
CochraneSoF table
33 questions
Ketamine and other glutamate receptor modulators for depression in adults with unipolar major depressive disorder
CochraneSoF table
15 questions
Internet‐based cognitive and behavioural therapies for post‐traumatic stress disorder (PTSD) in adults
CochraneSoF table
21 questions
Behavioural and cognitive behavioural therapy for obsessive compulsive disorder (OCD) in individuals with autism spectrum disorder (ASD)
CochraneSoF table
7 questions
Interventions for preventing type 2 diabetes in adults with mental disorders in low‐ and middle‐income countries
CochraneSoF table
18 questions
Approaches for discontinuation versus continuation of long‐term antidepressant use for depressive and anxiety disorders in adults
CochraneSoF table
32 questions
Magnetic seizure therapy for treatment‐resistant depression
CochraneSoF table
9 questions
Antidepressant treatment for postnatal depression
CochraneSoF table
37 questions
Lamotrigine in the maintenance treatment of bipolar disorder
CochraneSoF table
26 questions