Cochrane Review Group

Common Mental Disorders

117 systematic reviews in Common Mental Disorders ask 2,206 questions. 17.5% have no studies to answer them, 28.8% rest on very low certainty evidence and 22.9% reach moderate or high certainty.

Reviews
117
Questions
2,206
current versions
No studies
17.5%
Moderate or high
22.9%
No studies 387 · 17.5%Ungraded 111 · 5%Very low 635 · 28.8%Low 568 · 25.7%Moderate 449 · 20.4%High 56 · 2.5%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
Any psychological therapy vs any non‐therapy comparator: end‐of‐intervention and short‐term follow‐up
Depressive symptomatology (lower = less depressive symptomatology): end‐of‐intervention · older people with depression
Psychological therapies for depression in older adults residing in long‐term care settings (2024) · Cochrane
no estimate extracted18 studies · 644 participantsVery low
Any psychological therapy vs any non‐therapy comparator: end‐of‐intervention and short‐term follow‐up
Treatment non‐acceptability (higher = greater non‐acceptability): end‐of‐intervention · older people with depression
Psychological therapies for depression in older adults residing in long‐term care settings (2024) · Cochrane
no estimate extracted5 studies · 313 participantsVery low
Any psychological therapy vs any non‐therapy comparator: end‐of‐intervention and short‐term follow‐up
Depression remission (presence or absence of MDD):end‐of‐intervention · older people with depression
Psychological therapies for depression in older adults residing in long‐term care settings (2024) · Cochrane
no estimate extracted1 study · 82 participantsVery low
Any psychological therapy vs any non‐therapy comparator: end‐of‐intervention and short‐term follow‐up
Quality of life or psychological well‐being (higher = higher quality of life or psychological well‐being): end‐of‐intervention · older people with depression
Psychological therapies for depression in older adults residing in long‐term care settings (2024) · Cochrane
no estimate extracted6 studies · 195 participantsVery low
Any psychological therapy vs any non‐therapy comparator: end‐of‐intervention and short‐term follow‐up
Anxious symptomatology (lower = less anxious symptomatology): end‐of‐intervention · older people with depression
Psychological therapies for depression in older adults residing in long‐term care settings (2024) · Cochrane
no estimate extracted2 studies · 115 participantsVery low
Escitalopram vs placebo
PTSD severity at 3 months · adults experiencing acute traumatic stress symptoms
Early pharmacological interventions for prevention of post‐traumatic stress disorder (PTSD) in individuals… (2024) · Cochrane
no estimate extracted1 study · 23 participantsVery low
Hydrocortisone vs placebo
Quality of life at 3 months · adults experiencing acute traumatic stress symptoms
Early pharmacological interventions for prevention of post‐traumatic stress disorder (PTSD) in individuals… (2024) · Cochrane
no estimate extracted1 study · 43 participantsVery low
Escitalopram vs placebo
Dropouts due to adverse events at 3 months · adults experiencing acute traumatic stress symptoms
Early pharmacological interventions for prevention of post‐traumatic stress disorder (PTSD) in individuals… (2024) · Cochrane
no estimate extracted1 study · 31 participantsVery low
Escitalopram vs placebo
PTSD rate at 3 months · adults experiencing acute traumatic stress symptoms
Early pharmacological interventions for prevention of post‐traumatic stress disorder (PTSD) in individuals… (2024) · Cochrane
RR 0.59 [0.03, 13.08]1 study · 23 participantsVery low
Escitalopram vs placebo
Functional disability at 3 months ‐ not measured · adults experiencing acute traumatic stress symptoms
Early pharmacological interventions for prevention of post‐traumatic stress disorder (PTSD) in individuals… (2024) · Cochrane
no estimate extractedNRNo studies
Escitalopram vs placebo
Quality of life at 3 months ‐ not measured · adults experiencing acute traumatic stress symptoms
Early pharmacological interventions for prevention of post‐traumatic stress disorder (PTSD) in individuals… (2024) · Cochrane
no estimate extractedNRNo studies
Hydrocortisone vs placebo
PTSD severity at 3 months · adults experiencing acute traumatic stress symptoms
Early pharmacological interventions for prevention of post‐traumatic stress disorder (PTSD) in individuals… (2024) · Cochrane
no estimate extracted3 studies · 136 participantsVery low

Reviews 117

Melatonin and agomelatine for preventing seasonal affective disorder

Nussbaumer‐Streit, B, Greenblatt, A, et al. · Cochrane Database of Systematic Reviews · 2019
CochraneSoF table
6 questions

Psychological therapies for the treatment of depression in chronic obstructive pulmonary disease

Pollok, J, van Agteren, JEM, et al. · Cochrane Database of Systematic Reviews · 2019
CochraneSoF table
15 questions

Comparative effectiveness of continuation and maintenance treatments for persistent depressive disorder in adults

Machmutow, K, Meister, R, et al. · Cochrane Database of Systematic Reviews · 2019
CochraneSoF table
2 questions

Present‐centered therapy (PCT) for post‐traumatic stress disorder (PTSD) in adults

Belsher, BE, Beech, E, et al. · Cochrane Database of Systematic Reviews · 2019
CochraneSoF table
5 questions

Pharmacy‐based management for depression in adults

Brown, JVE, Walton, N, et al. · Cochrane Database of Systematic Reviews · 2019
CochraneSoF table
8 questions

Acupuncture for depression

Smith, CA, Armour, M, et al. · Cochrane Database of Systematic Reviews · 2018
CochraneSoF table
20 questions

Couple therapy for depression

Barbato, A, D'Avanzo, B, et al. · Cochrane Database of Systematic Reviews · 2018
CochraneSoF table
16 questions

Antidepressants for preventing postnatal depression

Molyneaux, E, Telesia, LA, et al. · Cochrane Database of Systematic Reviews · 2018
CochraneSoF table
12 questions

Antidepressants for depression in adults with HIV infection

Eshun‐Wilson, I, Siegfried, N, et al. · Cochrane Database of Systematic Reviews · 2018
CochraneSoF table
15 questions

Psychological therapies for treatment‐resistant depression in adults

Ijaz, S, Davies, P, et al. · Cochrane Database of Systematic Reviews · 2018
CochraneSoF table
17 questions

Antidepressants versus placebo for panic disorder in adults

Bighelli, I, Castellazzi, M, et al. · Cochrane Database of Systematic Reviews · 2018
CochraneSoF table
28 questions

Eszopiclone for insomnia

Rösner, S, Englbrecht, C, et al. · Cochrane Database of Systematic Reviews · 2018
CochraneSoF table
7 questions

Antidepressants for insomnia in adults

Everitt, H, Baldwin, DS, et al. · Cochrane Database of Systematic Reviews · 2018
CochraneSoF table
12 questions

Client feedback in psychological therapy for children and adolescents with mental health problems

Bergman, H, Kornør, H, et al. · Cochrane Database of Systematic Reviews · 2018
CochraneSoF table
5 questions

Psychological therapies for the treatment of mental disorders in low‐ and middle‐income countries affected by humanitarian crises

Purgato, M, Gastaldon, C, et al. · Cochrane Database of Systematic Reviews · 2018
CochraneSoF table
10 questions

Pharmacological interventions for the treatment of depression in chronic obstructive pulmonary disease

Pollok, J, van Agteren, JEM, et al. · Cochrane Database of Systematic Reviews · 2018
CochraneSoF table
14 questions

Psychological therapies for anxiety and depression in children and adolescents with long‐term physical conditions

Thabrew, H, Stasiak, K, et al. · Cochrane Database of Systematic Reviews · 2018
CochraneSoF table
7 questions

E‐Health interventions for anxiety and depression in children and adolescents with long‐term physical conditions

Thabrew, H, Stasiak, K, et al. · Cochrane Database of Systematic Reviews · 2018
CochraneSoF table
6 questions

Pharmacotherapy for social anxiety disorder (SAnD)

Williams, T, Hattingh, CJ, et al. · Cochrane Database of Systematic Reviews · 2017
CochraneSoF table
62 questions

Music therapy for depression

Aalbers, S, Fusar‐Poli, L, et al. · Cochrane Database of Systematic Reviews · 2017
CochraneSoF table
21 questions

Psychological therapies for the treatment of anxiety disorders in chronic obstructive pulmonary disease

Usmani, ZA, Carson, KV, et al. · Cochrane Database of Systematic Reviews · 2017
CochraneSoF table
5 questions

Vortioxetine for depression in adults

Koesters, M, Ostuzzi, G, et al. · Cochrane Database of Systematic Reviews · 2017
CochraneSoF table
14 questions

Cognitive behavioural therapy (CBT), third‐wave CBT and interpersonal therapy (IPT) based interventions for preventing depression in children and adolescents

Hetrick, SE, Cox, GR, et al. · Cochrane Database of Systematic Reviews · 2016
CochraneSoF table
6 questions

Topiramate for acute affective episodes in bipolar disorder in adults

Pigott, K, Galizia, I, et al. · Cochrane Database of Systematic Reviews · 2016
CochraneSoF table
29 questions

Continuation and maintenance treatments for depression in older people

Wilkinson, P, Izmeth, Z · Cochrane Database of Systematic Reviews · 2016
CochraneSoF table
2 questions