Cochrane Review Group
Common Mental Disorders
117 systematic reviews in Common Mental Disorders ask 2,206 questions. 17.5% have no studies to answer them, 28.8% rest on very low certainty evidence and 22.9% reach moderate or high certainty.
Reviews
117
Questions
2,206
current versions
No studies
17.5%
Moderate or high
22.9%
No studies 387 · 17.5%Ungraded 111 · 5%Very low 635 · 28.8%Low 568 · 25.7%Moderate 449 · 20.4%High 56 · 2.5%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Thinnest evidence
All no studies and very low questions| Question | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Any psychological therapy vs any non‐therapy comparator: end‐of‐intervention and short‐term follow‐up Depressive symptomatology (lower = less depressive symptomatology): end‐of‐intervention · older people with depression Psychological therapies for depression in older adults residing in long‐term care settings (2024) · Cochrane | no estimate extracted | 18 studies · 644 participants | Very low |
Any psychological therapy vs any non‐therapy comparator: end‐of‐intervention and short‐term follow‐up Treatment non‐acceptability (higher = greater non‐acceptability): end‐of‐intervention · older people with depression Psychological therapies for depression in older adults residing in long‐term care settings (2024) · Cochrane | no estimate extracted | 5 studies · 313 participants | Very low |
Any psychological therapy vs any non‐therapy comparator: end‐of‐intervention and short‐term follow‐up Depression remission (presence or absence of MDD):end‐of‐intervention · older people with depression Psychological therapies for depression in older adults residing in long‐term care settings (2024) · Cochrane | no estimate extracted | 1 study · 82 participants | Very low |
Any psychological therapy vs any non‐therapy comparator: end‐of‐intervention and short‐term follow‐up Quality of life or psychological well‐being (higher = higher quality of life or psychological well‐being): end‐of‐intervention · older people with depression Psychological therapies for depression in older adults residing in long‐term care settings (2024) · Cochrane | no estimate extracted | 6 studies · 195 participants | Very low |
Any psychological therapy vs any non‐therapy comparator: end‐of‐intervention and short‐term follow‐up Anxious symptomatology (lower = less anxious symptomatology): end‐of‐intervention · older people with depression Psychological therapies for depression in older adults residing in long‐term care settings (2024) · Cochrane | no estimate extracted | 2 studies · 115 participants | Very low |
Escitalopram vs placebo PTSD severity at 3 months · adults experiencing acute traumatic stress symptoms Early pharmacological interventions for prevention of post‐traumatic stress disorder (PTSD) in individuals… (2024) · Cochrane | no estimate extracted | 1 study · 23 participants | Very low |
Hydrocortisone vs placebo Quality of life at 3 months · adults experiencing acute traumatic stress symptoms Early pharmacological interventions for prevention of post‐traumatic stress disorder (PTSD) in individuals… (2024) · Cochrane | no estimate extracted | 1 study · 43 participants | Very low |
Escitalopram vs placebo Dropouts due to adverse events at 3 months · adults experiencing acute traumatic stress symptoms Early pharmacological interventions for prevention of post‐traumatic stress disorder (PTSD) in individuals… (2024) · Cochrane | no estimate extracted | 1 study · 31 participants | Very low |
Escitalopram vs placebo PTSD rate at 3 months · adults experiencing acute traumatic stress symptoms Early pharmacological interventions for prevention of post‐traumatic stress disorder (PTSD) in individuals… (2024) · Cochrane | RR 0.59 [0.03, 13.08] | 1 study · 23 participants | Very low |
Escitalopram vs placebo Functional disability at 3 months ‐ not measured · adults experiencing acute traumatic stress symptoms Early pharmacological interventions for prevention of post‐traumatic stress disorder (PTSD) in individuals… (2024) · Cochrane | no estimate extracted | NR | No studies |
Escitalopram vs placebo Quality of life at 3 months ‐ not measured · adults experiencing acute traumatic stress symptoms Early pharmacological interventions for prevention of post‐traumatic stress disorder (PTSD) in individuals… (2024) · Cochrane | no estimate extracted | NR | No studies |
Hydrocortisone vs placebo PTSD severity at 3 months · adults experiencing acute traumatic stress symptoms Early pharmacological interventions for prevention of post‐traumatic stress disorder (PTSD) in individuals… (2024) · Cochrane | no estimate extracted | 3 studies · 136 participants | Very low |
Reviews 117
Non‐pharmacological interventions for somatoform disorders and medically unexplained physical symptoms (MUPS) in adults
CochraneSoF table
12 questions
Tricyclic drugs for depression in children and adolescents
CochraneSoF table
4 questions
Strategies for managing sexual dysfunction induced by antidepressant medication
CochraneSoF table
9 questions
Psychological therapies for chronic post‐traumatic stress disorder (PTSD) in adults
CochraneSoF table
24 questions
Fluoxetine versus other types of pharmacotherapy for depression
CochraneSoF table
130 questions
Exercise for depression
CochraneSoF table
13 questions
Aripiprazole alone or in combination for acute mania
CochraneSoF table
12 questions
Media‐delivered cognitive behavioural therapy and behavioural therapy (self‐help) for anxiety disorders in adults
CochraneSoF table
8 questions
Behavioural therapies versus other psychological therapies for depression
CochraneSoF table
15 questions
'Third wave' cognitive and behavioural therapies versus other psychological therapies for depression
CochraneSoF table
7 questions
'Third wave' cognitive and behavioural therapies versus treatment as usual for depression
CochraneSoF table
6 questions
Agomelatine versus other antidepressive agents for major depression
CochraneSoF table
12 questions
Newer generation antidepressants for depressive disorders in children and adolescents
CochraneSoF table
5 questions
Interventions to facilitate return to work in adults with adjustment disorders
CochraneSoF table
4 questions
Interventions for preventing relapse and recurrence of a depressive disorder in children and adolescents
CochraneSoF table
3 questions
Psychological therapies for pathological and problem gambling
CochraneSoF table
12 questions
Amitriptyline versus placebo for major depressive disorder
CochraneSoF table
5 questions