Cochrane · systematic review · CD007504
Interventions for preventing relapse and recurrence of a depressive disorder in children and adolescents
Cox, GR, Fisher, CA, De Silva, S, et al. · Cochrane Database of Systematic Reviews · 2012 · Cochrane Library
Common Mental DisordersAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
3
current version
GRADE rated
3
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 1 · 33.3%Moderate 2 · 66.7%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Medication compared to placebo for preventing relapse and recurrence of a depressive disorder in children and adolescents
Population: patients with preventing relapse and recurrence of a depressive disorder in children and adolescents
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Number relapsed‐recurred Medication vs placebo | OR 0.34 [0.18, 0.64] | 3 studies · 164 participants | Moderate Downgraded: risk of bias |
Suicide‐related behaviours Medication vs placebo | OR 1.02 [0.14, 7.39] | 3 studies · 164 participants | Low Downgraded: risk of bias |
Drop‐outs Medication vs placebo | OR 1.02 [0.38, 2.79] | 3 studies · 164 participants | Moderate |