Cochrane · systematic review · CD003388
Psychological therapies for chronic post‐traumatic stress disorder (PTSD) in adults
Bisson, JI, Roberts, NP, Andrew, M, et al. · Cochrane Database of Systematic Reviews · 2013 · Cochrane Library
Common Mental DisordersAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
24
current version
GRADE rated
24
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 24 · 100%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Trauma‐focused CBT/Exposure therapy compared with Waitlist/Usual Care for chronic post‐traumatic stress disorder (PTSD) in adults
Population: Adults with PTSD for at least 3 months
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Severity of PTSD symptoms ‐ Clinician‐rated Trauma‐focused CBT/Exposure therapy vs Waitlist/Usual Care | no estimate extracted | 28 studies · 1256 participants | Very low Downgraded: risk of bias, imprecision, inconsistency |
Leaving the study early for any reason Trauma‐focused CBT/Exposure therapy vs Waitlist/Usual Care | RR 1.64 [1.3, 2.06] | 33 studies · 1756 participants | Very low Downgraded: risk of bias, imprecision, inconsistency |
Trauma‐focused CBT/Exposure therapy compared with non‐TFCBT for chronic post‐traumatic stress disorder (PTSD) in adults
Population: Adults with PTSD for at least 3 months
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Severity of PTSD Symptoms ‐ Clinician‐rated Trauma‐focused CBT/Exposure therapy vs non‐TFCBT | no estimate extracted | 7 studies · 267 participants | Very low Downgraded: risk of bias, inconsistency |
Leaving the study early for any reason Trauma‐focused CBT/Exposure therapy vs non‐TFCBT | RR 1.19 [0.71, 2] | 7 studies · 312 participants | Very low Downgraded: risk of bias, imprecision, inconsistency |
Trauma‐focused CBT/Exposure therapy compared with other therapies for chronic post‐traumatic stress disorder (PTSD) in adults
Population: Adults with PTSD for at least 3 months
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Severity of PTSD symptoms ‐ Clinician‐rated Trauma‐focused CBT/Exposure therapy vs other therapies | no estimate extracted | 10 studies · 612 participants | Very low Downgraded: risk of bias, imprecision, inconsistency |
Leaving the study early for any reason Trauma‐focused CBT/Exposure therapy vs other therapies | RR 1.39 [1.01, 1.92] | 11 studies · 762 participants | Very low Downgraded: risk of bias, imprecision, inconsistency |
EMDR compared with Waitlist/Usual Care for chronic post‐traumatic stress disorder (PTSD) in adults
Population: Adults with PTSD for at least 3 months
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Severity of PTSD symptoms ‐ Clinician‐rated EMDR vs Waitlist/Usual Care | no estimate extracted | 6 studies · 183 participants | Very low Downgraded: risk of bias, imprecision, inconsistency |
Leaving study early for any reason EMDR vs Waitlist/Usual Care | RR 1.05 [0.62, 1.79] | 7 studies · 227 participants | Very low Downgraded: risk of bias, imprecision |
EMDR compared with Trauma‐focused CBT for chronic post‐traumatic stress disorder (PTSD) in adults
Population: Adults with PTSD for at least 3 months
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Severity of PTSD symptoms ‐ Clinician‐rated EMDR vs Trauma‐focused CBT | no estimate extracted | 7 studies · 327 participants | Very low Downgraded: risk of bias, imprecision, inconsistency |
Leaving study early for any reason EMDR vs Trauma‐focused CBT | RR 1 [0.74, 1.35] | 8 studies · 400 participants | Very low Downgraded: risk of bias, imprecision, inconsistency |
EMDR compared with non‐TFCBT for chronic post‐traumatic stress disorder (PTSD) in adults
Population: Adults with PTSD for at least 3 months
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Severity of PTSD symptoms ‐ Clinician‐rated EMDR vs non‐TFCBT | no estimate extracted | 2 studies · 53 participants | Very low Downgraded: risk of bias, imprecision |
Leaving the study early for any reason EMDR vs non‐TFCBT | RR 1.03 [0.37, 2.88] | 3 studies · 84 participants | Very low Downgraded: risk of bias, imprecision |
EMDR compared with other therapies for chronic post‐traumatic stress disorder (PTSD) in adults
Population: Adults with PTSD for at least 3 months
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Leaving study early for any reason EMDR vs other therapies | RR 1.48 [0.26, 8.54] | 2 studies · 127 participants | Very low Downgraded: risk of bias, imprecision |
Non‐TFCBT compared with Waitlist/Usual Care for chronic post‐traumatic stress disorder (PTSD) in adults
Population: Adults with PTSD for at least 3 months
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Severity of PTSD symptoms ‐ Clinician‐rated Non‐TFCBT vs Waitlist/Usual Care | no estimate extracted | 4 studies · 106 participants | Very low Downgraded: risk of bias, imprecision, inconsistency |
Leaving the study early due to any reason Non‐TFCBT vs Waitlist/Usual Care | RR 1.96 [0.7, 5.48] | 5 studies · 141 participants | Very low Downgraded: risk of bias, imprecision, inconsistency |
Non‐TFCBT compared with other therapies for chronic post‐traumatic stress disorder (PTSD) in adults
Population: Adults with PTSD for at least 3 months
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Severity of PTSD symptoms ‐ Clincian‐rated Non‐TFCBT vs other therapies | no estimate extracted | 1 study · 25 participants | Very low Downgraded: risk of bias, imprecision, inconsistency |
Leaving the study early for any reason Non‐TFCBT vs other therapies | no estimate extracted | 1 study · 31 participants | Very low Downgraded: risk of bias, imprecision, inconsistency |
Group TFCBT compared with Waitlist/Usual Care for chronic post‐traumatic stress disorder (PTSD) in adults
Population: Adults with PTSD for at least 3 months
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Severity of PTSD symptoms ‐ Clinician‐rated Group TFCBT vs Waitlist/Usual Care | no estimate extracted | 3 studies · 185 participants | Very low Downgraded: risk of bias, imprecision, inconsistency |
Leaving the study early for any reason Group TFCBT vs Waitlist/Usual Care | RR 1.21 [0.94, 1.55] | 7 studies · 573 participants | Very low Downgraded: risk of bias, imprecision, inconsistency |
Group TFCBT compared with Group non‐TFCBT for chronic post‐traumatic stress disorder (PTSD) in adults
Population: Adults with PTSD for at least 3 months
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Severity of PTSD symptoms ‐ Clinician‐rated Group TFCBT vs Group non‐TFCBT | no estimate extracted | 1 study · 325 participants | Very low Downgraded: risk of bias, imprecision |
Leaving the study early for any reason Group TFCBT vs Group non‐TFCBT | no estimate extracted | 1 study · 360 participants | Very low Downgraded: risk of bias, imprecision |
Other therapies compared with Waitlist/Usual Care for chronic post‐traumatic stress disorder (PTSD) in adults
Population: Adults with PTSD for at least 3 months
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Severity of PTSD symptoms ‐ Clinician Other therapies vs Waitlist/Usual Care | no estimate extracted | 3 studies · 112 participants | Very low Downgraded: imprecision |
Leaving the study early due to any reason Other therapies vs Waitlist/Usual Care | RR 2.45 [0.99, 6.1] | 4 studies · 211 participants | Very low Downgraded: risk of bias, imprecision |
Group non‐TFCBT compared with Waitlist/Usual Care for chronic post‐traumatic stress disorder (PTSD) in adults
Population: Adults with PTSD for at least 3 months
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Leaving the study early for any reason Group non‐TFCBT vs Waitlist/Usual Care | no estimate extracted | 1 study · 47 participants | Very low Downgraded: risk of bias, imprecision |