Cochrane · systematic review · CD013299

Pharmacy‐based management for depression in adults

Brown, JVE, Walton, N, Meader, N, et al. · Cochrane Database of Systematic Reviews · 2019 · Cochrane Library

Common Mental DisordersAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
8
current version
GRADE rated
4
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 4 · 50%Very low 0 · 0%Low 1 · 12.5%Moderate 1 · 12.5%High 2 · 25%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Pharmacy‐based management (pharmacist with or without wider team) compared to treatment as usual for depression in adults

Population: adults
8 questions
OutcomeEffectEvidenceStatus / GRADE
Depression symptom level: improvement (intervention endpoint)
Pharmacy‐based management (pharmacist with or without wider team) vs treatment
RR 0.95 [0.86, 1.05]4 studies · 475 participantsModerate
Depression symptom level: change from baseline mean depression score (intervention endpoint)
Pharmacy‐based management (pharmacist with or without wider team) vs treatment
no estimate extracted5 studies · 718 participantsHigh
Acceptability of the intervention (as measured by participants not attending
Pharmacy‐based management (pharmacist with or without wider team) vs treatment
RR 1.09 [0.81, 1.45]12 studies · 2072 participantsLow
Diagnosis of depression
Pharmacy‐based management (pharmacist with or without wider team) vs treatment
no estimate extracted3 studies · 368 participantsUngraded
Non‐adherence to medication
Pharmacy‐based management (pharmacist with or without wider team) vs treatment
RR 0.73 [0.61, 0.87]6 studies · 911 participantsHigh
Frequency of primary care appointments
Pharmacy‐based management (pharmacist with or without wider team) vs treatment
no estimate extracted1 study · 74 participantsUngraded
Quality of life
Pharmacy‐based management (pharmacist with or without wider team) vs treatment
no estimate extracted1 study · 239 participantsUngraded
Social functioning
Pharmacy‐based management (pharmacist with or without wider team) vs treatment
no estimate extracted1 study · 125 participantsUngraded