Cochrane Review Group

Common Mental Disorders

117 systematic reviews in Common Mental Disorders ask 2,206 questions. 17.5% have no studies to answer them, 28.8% rest on very low certainty evidence and 22.9% reach moderate or high certainty.

Reviews
117
Questions
2,206
current versions
No studies
17.5%
Moderate or high
22.9%
No studies 387 · 17.5%Ungraded 111 · 5%Very low 635 · 28.8%Low 568 · 25.7%Moderate 449 · 20.4%High 56 · 2.5%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
Any psychological therapy vs any non‐therapy comparator: end‐of‐intervention and short‐term follow‐up
Depressive symptomatology (lower = less depressive symptomatology): end‐of‐intervention · older people with depression
Psychological therapies for depression in older adults residing in long‐term care settings (2024) · Cochrane
no estimate extracted18 studies · 644 participantsVery low
Any psychological therapy vs any non‐therapy comparator: end‐of‐intervention and short‐term follow‐up
Treatment non‐acceptability (higher = greater non‐acceptability): end‐of‐intervention · older people with depression
Psychological therapies for depression in older adults residing in long‐term care settings (2024) · Cochrane
no estimate extracted5 studies · 313 participantsVery low
Any psychological therapy vs any non‐therapy comparator: end‐of‐intervention and short‐term follow‐up
Depression remission (presence or absence of MDD):end‐of‐intervention · older people with depression
Psychological therapies for depression in older adults residing in long‐term care settings (2024) · Cochrane
no estimate extracted1 study · 82 participantsVery low
Any psychological therapy vs any non‐therapy comparator: end‐of‐intervention and short‐term follow‐up
Quality of life or psychological well‐being (higher = higher quality of life or psychological well‐being): end‐of‐intervention · older people with depression
Psychological therapies for depression in older adults residing in long‐term care settings (2024) · Cochrane
no estimate extracted6 studies · 195 participantsVery low
Any psychological therapy vs any non‐therapy comparator: end‐of‐intervention and short‐term follow‐up
Anxious symptomatology (lower = less anxious symptomatology): end‐of‐intervention · older people with depression
Psychological therapies for depression in older adults residing in long‐term care settings (2024) · Cochrane
no estimate extracted2 studies · 115 participantsVery low
Escitalopram vs placebo
PTSD severity at 3 months · adults experiencing acute traumatic stress symptoms
Early pharmacological interventions for prevention of post‐traumatic stress disorder (PTSD) in individuals… (2024) · Cochrane
no estimate extracted1 study · 23 participantsVery low
Hydrocortisone vs placebo
Quality of life at 3 months · adults experiencing acute traumatic stress symptoms
Early pharmacological interventions for prevention of post‐traumatic stress disorder (PTSD) in individuals… (2024) · Cochrane
no estimate extracted1 study · 43 participantsVery low
Escitalopram vs placebo
Dropouts due to adverse events at 3 months · adults experiencing acute traumatic stress symptoms
Early pharmacological interventions for prevention of post‐traumatic stress disorder (PTSD) in individuals… (2024) · Cochrane
no estimate extracted1 study · 31 participantsVery low
Escitalopram vs placebo
PTSD rate at 3 months · adults experiencing acute traumatic stress symptoms
Early pharmacological interventions for prevention of post‐traumatic stress disorder (PTSD) in individuals… (2024) · Cochrane
RR 0.59 [0.03, 13.08]1 study · 23 participantsVery low
Escitalopram vs placebo
Functional disability at 3 months ‐ not measured · adults experiencing acute traumatic stress symptoms
Early pharmacological interventions for prevention of post‐traumatic stress disorder (PTSD) in individuals… (2024) · Cochrane
no estimate extractedNRNo studies
Escitalopram vs placebo
Quality of life at 3 months ‐ not measured · adults experiencing acute traumatic stress symptoms
Early pharmacological interventions for prevention of post‐traumatic stress disorder (PTSD) in individuals… (2024) · Cochrane
no estimate extractedNRNo studies
Hydrocortisone vs placebo
PTSD severity at 3 months · adults experiencing acute traumatic stress symptoms
Early pharmacological interventions for prevention of post‐traumatic stress disorder (PTSD) in individuals… (2024) · Cochrane
no estimate extracted3 studies · 136 participantsVery low

Reviews 117

Interventions for self‐harm in children and adolescents

Witt, KG, Hetrick, SE, et al. · Cochrane Database of Systematic Reviews · 2021
CochraneSoF table
4 questions

Psychosocial interventions for self‐harm in adults

Witt, KG, Hetrick, SE, et al. · Cochrane Database of Systematic Reviews · 2021
CochraneSoF table
24 questions

Pharmacological interventions for self‐harm in adults

Witt, KG, Hetrick, SE, et al. · Cochrane Database of Systematic Reviews · 2021
CochraneSoF table
7 questions

New generation antidepressants for depression in children and adolescents: a network meta‐analysis

Hetrick, SE, McKenzie, JE, et al. · Cochrane Database of Systematic Reviews · 2021
CochraneSoF table
121 questions

Mindfulness‐based psychological interventions for improving mental well‐being in medical students and junior doctors

Sekhar, P, Tee, QX, et al. · Cochrane Database of Systematic Reviews · 2021
CochraneSoF table
11 questions

Psychosocial interventions for conversion and dissociative disorders in adults

Ganslev, CA, Storebø, OJ, et al. · Cochrane Database of Systematic Reviews · 2020
CochraneSoF table
51 questions

Psychological and social interventions for the prevention of mental disorders in people living in low‐ and middle‐income countries affected by humanitarian crises

Papola, D, Purgato, M, et al. · Cochrane Database of Systematic Reviews · 2020
CochraneSoF table
12 questions

Psychological therapies for women who experience intimate partner violence

Hameed, M, O'Doherty, L, et al. · Cochrane Database of Systematic Reviews · 2020
CochraneSoF table
7 questions

Cognitive behavioural therapy for anxiety disorders in children and adolescents

James, AC, Reardon, T, et al. · Cochrane Database of Systematic Reviews · 2020
CochraneSoF table
32 questions

Behavioural activation therapy for depression in adults

Uphoff, E, Ekers, D, et al. · Cochrane Database of Systematic Reviews · 2020
CochraneSoF table
49 questions

Behavioural activation therapy for depression in adults with non‐communicable diseases

Uphoff, E, Pires, M, et al. · Cochrane Database of Systematic Reviews · 2020
CochraneSoF table
14 questions

Means restriction for the prevention of suicide by jumping

Okolie, C, Wood, S, et al. · Cochrane Database of Systematic Reviews · 2020
CochraneSoF table
25 questions

Antidepressants plus benzodiazepines for adults with major depression

Ogawa, Y, Takeshima, N, et al. · Cochrane Database of Systematic Reviews · 2019
CochraneSoF table
6 questions

Exercise therapy for chronic fatigue syndrome

Larun, L, Brurberg, KG, et al. · Cochrane Database of Systematic Reviews · 2019
CochraneSoF table
55 questions

Lithium for acute mania

McKnight, RF, de La Motte de Broöns de Vauvert, SJ, et al. · Cochrane Database of Systematic Reviews · 2019
CochraneSoF table
82 questions

Valproate for acute mania

Jochim, J, Rifkin‐Zybutz, RP, et al. · Cochrane Database of Systematic Reviews · 2019
CochraneSoF table
30 questions

Family therapy approaches for anorexia nervosa

Fisher, CA, Skocic, S, et al. · Cochrane Database of Systematic Reviews · 2019
CochraneSoF table
7 questions

Multiple session early psychological interventions for the prevention of post‐traumatic stress disorder

Roberts, NP, Kitchiner, NJ, et al. · Cochrane Database of Systematic Reviews · 2019
CochraneSoF table
12 questions

Pharmacological interventions for treatment‐resistant depression in adults

Davies, P, Ijaz, S, et al. · Cochrane Database of Systematic Reviews · 2019
CochraneSoF table
41 questions

Benzodiazepines versus placebo for panic disorder in adults

Breilmann, J, Girlanda, F, et al. · Cochrane Database of Systematic Reviews · 2019
CochraneSoF table
6 questions

Inpatient versus outpatient care, partial hospitalisation and waiting list for people with eating disorders

Hay, PJ, Touyz, S, et al. · Cochrane Database of Systematic Reviews · 2019
CochraneSoF table
2 questions

Couple and family therapies for post‐traumatic stress disorder (PTSD)

Suomi, A, Evans, L, et al. · Cochrane Database of Systematic Reviews · 2019
CochraneSoF table
27 questions

Second‐generation antidepressants for preventing seasonal affective disorder in adults

Gartlehner, G, Nussbaumer‐Streit, B, et al. · Cochrane Database of Systematic Reviews · 2019
CochraneSoF table
7 questions

Light therapy for preventing seasonal affective disorder

Nussbaumer‐Streit, B, Forneris, CA, et al. · Cochrane Database of Systematic Reviews · 2019
CochraneSoF table
12 questions

Psychological therapies for preventing seasonal affective disorder

Forneris, CA, Nussbaumer‐Streit, B, et al. · Cochrane Database of Systematic Reviews · 2019
CochraneSoF table
3 questions