Cochrane · systematic review · CD013162
Cognitive behavioural therapy for anxiety disorders in children and adolescents
James, AC, Reardon, T, Soler, A, et al. · Cochrane Database of Systematic Reviews · 2020 · Cochrane Library
Common Mental DisordersAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
32
current version
GRADE rated
22
No studies
10
Included studies
NR
No studies 10 · 31.3%Ungraded 0 · 0%Very low 0 · 0%Low 18 · 56.3%Moderate 4 · 12.5%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
CBT compared with waitlist for children and adolescents with anxiety disorders
Population: children and adolescents with anxiety disorders
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Remission of primary anxiety diagnosis post‐treatment (ITT) CBT vs waitlist | OR 5.45 [3.9, 7.6] | 39 studies · 2697 participants | Moderate Downgraded: inconsistency |
Acceptability (number of participants lost to post‐treatment assessment) CBT vs waitlist | OR 1.09 [0.85, 1.41] | 45 studies · 3158 participants | Low Downgraded: imprecision, inconsistency |
Remission of all anxiety diagnoses post‐treatment (ITT) CBT vs waitlist | OR 4.43 [2.89, 6.78] | 28 studies · 2075 participants | Moderate Downgraded: inconsistency |
Reduction in anxiety symptoms (child report) post‐treatment CBT vs waitlist | no estimate extracted | 45 studies · 2831 participants | Low Downgraded: inconsistency |
Reduction in anxiety symptoms (parent report) post‐treatment CBT vs waitlist | no estimate extracted | 35 studies · 2137 participants | Low Downgraded: inconsistency |
Reduction in depressive symptoms post‐treatment CBT vs waitlist | no estimate extracted | 17 studies · 1157 participants | Moderate Downgraded: inconsistency |
Improvement in global functioning post‐treatment CBT vs waitlist | no estimate extracted | 11 studies · 557 participants | Low Downgraded: risk of bias, imprecision, inconsistency |
Adverse events (randomisation to post‐treatment) CBT vs waitlist | no estimate extracted | NR | No studies |
CBT compared with treatment as usual for anxiety disorders in children and adolescents
Population: children and adolescents with anxiety disorders
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Remission of primary anxiety diagnosis post‐treatment (ITT) CBT vs treatment | OR 3.19 [0.9, 11.29] | 8 studies · 487 participants | Low Downgraded: imprecision, inconsistency |
Acceptability (number of participants lost to post‐treatment assessment) CBT vs treatment | OR 1.37 [0.73, 2.56] | 8 studies · 441 participants | Low Downgraded: imprecision, inconsistency |
Remission of all anxiety diagnoses post‐treatment (ITT) CBT vs treatment | OR 2.74 [1.16, 6.46] | 5 studies · 203 participants | Low Downgraded: imprecision, inconsistency |
Reduction in anxiety symptoms (child report) post‐treatment CBT vs treatment | no estimate extracted | 6 studies · 214 participants | Low Downgraded: imprecision, inconsistency |
Reduction in anxiety symptoms (parent report) post‐treatment CBT vs treatment | no estimate extracted | 7 studies · 228 participants | Low Downgraded: imprecision, inconsistency |
Reduction in depressive symptoms post‐treatment CBT vs treatment | no estimate extracted | NR | No studies |
Improvement in global functioning post‐treatment CBT vs treatment | no estimate extracted | NR | No studies |
Adverse events (randomisation to post‐treatment) CBT vs treatment | no estimate extracted | NR | No studies |
CBT compared with attention control for anxiety disorders in children and adolescents
Population: children and adolescents with anxiety disorders
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Remission of primary anxiety diagnosis post‐treatment (ITT) CBT vs attention control | OR 2.28 [1.33, 3.89] | 10 studies · 822 participants | Low Downgraded: imprecision, inconsistency |
Acceptability (number of participants lost to post‐treatment assessment) CBT vs attention control | OR 1 [0.68, 1.49] | 12 studies · 797 participants | Low Downgraded: imprecision, inconsistency |
Remission of all anxiety diagnoses post‐treatment (ITT) CBT vs attention control | OR 2.75 [1.22, 6.17] | 5 studies · 378 participants | Low Downgraded: imprecision, inconsistency |
Reduction in anxiety symptoms (child report) post‐treatment CBT vs attention control | no estimate extracted | 15 studies · 978 participants | Moderate Downgraded: inconsistency |
Reduction in anxiety symptoms (parent report) post‐treatment CBT vs attention control | no estimate extracted | 8 studies · 638 participants | Low Downgraded: imprecision, inconsistency |
Reduction in depressive symptoms post‐treatment CBT vs attention control | no estimate extracted | 10 studies · 613 participants | Low Downgraded: imprecision, inconsistency |
Improvement in global functioning post‐treatment CBT vs attention control | no estimate extracted | NR | No studies |
Adverse events (randomisation to post‐treatment) CBT vs attention control | no estimate extracted | NR | No studies |
CBT compared with alternative treatment for anxiety disorders in children and adolescents
Population: children and adolescents with anxiety disorders
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Remission of primary anxiety diagnosis post‐treatment (ITT) CBT vs alternative treatment | no estimate extracted | NR | No studies |
Acceptability (number of participants lost to post‐treatment assessment) CBT vs alternative treatment | OR 1.58 [0.61, 4.13] | 7 studies · 515 participants | Low Downgraded: imprecision, inconsistency |
Remission of all anxiety diagnoses post‐treatment (ITT) CBT vs alternative treatment | OR 0.89 [0.35, 2.23] | 4 studies · 401 participants | Low Downgraded: imprecision, inconsistency |
Reduction in anxiety symptoms (child report) post‐treatment CBT vs alternative treatment | no estimate extracted | 6 studies · 399 participants | Low Downgraded: imprecision, inconsistency |
Reduction in anxiety symptoms (parent report) post‐treatment CBT vs alternative treatment | no estimate extracted | 6 studies · 423 participants | Low Downgraded: imprecision, inconsistency |
Reduction in depressive symptoms post‐treatment CBT vs alternative treatment | no estimate extracted | NR | No studies |
Improvement in global functioning post‐treatment CBT vs alternative treatment | no estimate extracted | NR | No studies |
Adverse events (randomisation to post‐treatment) CBT vs alternative treatment | no estimate extracted | NR | No studies |