Cochrane · systematic review · CD004517

Music therapy for depression

Aalbers, S, Fusar‐Poli, L, Freeman, RE, et al. · Cochrane Database of Systematic Reviews · 2017 · Cochrane Library

Common Mental DisordersAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
21
current version
GRADE rated
15
No studies
6
Included studies
NR
No studies 6 · 28.6%Ungraded 0 · 0%Very low 6 · 28.6%Low 5 · 23.8%Moderate 4 · 19%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Music therapy plus treatment as usual (TAU) versus TAU for depression (primary comparison)

Population: individuals with depression
7 questions
OutcomeEffectEvidenceStatus / GRADE
Depressive symptoms (clinician‐rated) (various scales) Up to 3 months
Music therapy plus treatment as usual (TAU) vs TAU
no estimate extracted3 studies · 219 participantsModerate
Downgraded: risk of bias
Depressive symptoms (patient‐reported) (various scales) Up to 3 months
Music therapy plus treatment as usual (TAU) vs TAU
no estimate extracted3 studies · 142 participantsModerate
Downgraded: risk of bias
Any adverse events Up to 3 months
Music therapy plus treatment as usual (TAU) vs TAU
OR 0.45 [0.02, 11.46]1 study · 79 participantsLow
Downgraded: risk of bias, imprecision, inconsistency
Functioning (GAF) Up to 3 months
Music therapy plus treatment as usual (TAU) vs TAU
no estimate extracted1 study · 67 participantsLow
Downgraded: risk of bias, imprecision, inconsistency
Quality of life (RAND‐36) Up to 3 months
Music therapy plus treatment as usual (TAU) vs TAU
no estimate extracted1 study · 67 participantsLow
Downgraded: risk of bias, imprecision, inconsistency
Leaving the study early Up to 3 months
Music therapy plus treatment as usual (TAU) vs TAU
OR 0.49 [0.14, 1.7]5 studies · 293 participantsModerate
Downgraded: risk of bias
Anxiety (HADS‐A) Up to 3 months
Music therapy plus treatment as usual (TAU) vs TAU
no estimate extracted2 studies · 195 participantsLow
Downgraded: risk of bias

Music therapy versus psychological treatment for depression

Population: adults with depression
7 questions
OutcomeEffectEvidenceStatus / GRADE
Depressive symptoms (clinician‐rated) (MADRS) Up to 3 months
Music therapy vs psychological treatment
no estimate extracted1 study · 11 participantsVery low
Downgraded: risk of bias
Depressive symptoms (patient‐reported) (various scales) Up to 3 months
Music therapy vs psychological treatment
no estimate extracted4 studies · 131 participantsLow
Downgraded: risk of bias
Any adverse events ‐ not reported
Music therapy vs psychological treatment
no estimate extractedNRNo studies
Functioning ‐ not reported
Music therapy vs psychological treatment
no estimate extractedNRNo studies
Quality of life (Thai RAND‐36) Up to 3 months
Music therapy vs psychological treatment
no estimate extracted1 study · 11 participantsVery low
Downgraded: risk of bias
Leaving the study early Up to 3 months
Music therapy vs psychological treatment
OR 0.17 [0.02, 1.49]4 studies · 157 participantsModerate
Downgraded: risk of bias
Anxiety ‐ not reported
Music therapy vs psychological treatment
no estimate extractedNRNo studies

Active music therapy versus receptive music therapy for depression

Population: adults with depression
7 questions
OutcomeEffectEvidenceStatus / GRADE
Depressive symptoms (clinician‐rated) (MADRS) Up to 3 months
Active music therapy vs receptive music therapy
no estimate extracted1 study · 9 participantsVery low
Downgraded: risk of bias
Depressive symptoms (patient‐reported) (TDI) Up to 3 months
Active music therapy vs receptive music therapy
no estimate extracted1 study · 9 participantsVery low
Downgraded: risk of bias
Any adverse events ‐ not reported
Active music therapy vs receptive music therapy
no estimate extractedNRNo studies
Functioning ‐ not reported
Active music therapy vs receptive music therapy
no estimate extractedNRNo studies
Quality of life (SF‐36 Thai) Up to 3 months
Active music therapy vs receptive music therapy
no estimate extracted1 study · 9 participantsVery low
Downgraded: risk of bias
Leaving the study early Up to 3 months
Active music therapy vs receptive music therapy
OR 0.27 [0.01, 8.46]1 study · 10 participantsVery low
Downgraded: risk of bias
Anxiety ‐ not reported
Active music therapy vs receptive music therapy
no estimate extractedNRNo studies