Cochrane · systematic review · CD010204
Psychological therapies for post‐traumatic stress disorder and comorbid substance use disorder
Roberts, NP, Roberts, PA, Jones, N, et al. · Cochrane Database of Systematic Reviews · 2016 · Cochrane Library
Common Mental DisordersAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
15
current version
GRADE rated
13
No studies
2
Included studies
NR
No studies 2 · 13.3%Ungraded 0 · 0%Very low 5 · 33.3%Low 8 · 53.3%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Comparison
Population: Individuals with post‐traumatic stress disorder and comorbid substance use disorder
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
PTSD severity following treatment completion As assessed by the CAPS, PSS‐I, or IES‐R. High scores indicate greater symptom severity | no estimate extracted | 4 studies · 405 participants | Very low Downgraded: risk of bias, inconsistency |
Drug or alcohol use, or both following treatment completion As assessed by the TLFB or CIDI. High scores indicate greater symptom severity | no estimate extracted | 3 studies · 388 participants | Very low Downgraded: risk of bias, inconsistency |
Treatment completers | RR 0.8 [0.69, 0.93] | 3 studies · 316 participants | Low Downgraded: risk of bias, inconsistency |
Trauma‐focused psychological intervention compared to active psychological intervention for SUD only
Population: Individuals with post‐traumatic stress disorder and comorbid substance use disorder
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
PTSD severity following treatment completion As assessed by the CAPS. High scores indicate greater symptom severity Trauma‐focused psychological intervention vs active psychological intervention | no estimate extracted | 1 study · 46 participants | Low Downgraded: imprecision |
Drug or alcohol use, or both following treatment completion As assessed by the TLFB. High scores indicate greater symptom severity Trauma‐focused psychological intervention vs active psychological intervention | no estimate extracted | 1 study · 46 participants | Low Downgraded: imprecision |
Treatment completers Trauma‐focused psychological intervention vs active psychological intervention | RR 1 [0.74, 1.36] | 1 study · 62 participants | Low Downgraded: imprecision |
Non‐trauma‐focused psychological intervention for PTSD and SUD or PTSD only compared to control intervention
Population: Individuals with post‐traumatic stress disorder and comorbid substance use disorder
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
PTSD severity following treatment completion ‐ Individual‐based intervention As assessed by the CAPS. High scores indicate greater symptom severity Non‐trauma‐focused psychological intervention for PTSD and SUD or PTSD only vs control intervention | no estimate extracted | 1 study · 44 participants | Low Downgraded: imprecision |
PTSD severity following treatment completion ‐ Group‐based intervention As assessed by the CAPS or IES‐R. High scores indicate greater symptom severity Non‐trauma‐focused psychological intervention for PTSD and SUD or PTSD only vs control intervention | no estimate extracted | 4 studies · 513 participants | Low Downgraded: risk of bias, inconsistency |
Drug or alcohol use, or both following treatment completion ‐ Individual‐based intervention Non‐trauma‐focused psychological intervention for PTSD and SUD or PTSD only vs control intervention | no estimate extracted | NR | No studies |
Drug or alcohol use, or both following treatment completion ‐ Group‐based intervention As assessed by the ASI, TLFB or CIDI. High scores indicate greater symptom severity Non‐trauma‐focused psychological intervention for PTSD and SUD or PTSD only vs control intervention | no estimate extracted | 3 studies · 464 participants | Very low Downgraded: risk of bias, inconsistency |
Treatment completers ‐ Individual‐based intervention Non‐trauma‐focused psychological intervention for PTSD and SUD or PTSD only vs control intervention | no estimate extracted | NR | No studies |
Treatment completers ‐ Group‐based intervention Non‐trauma‐focused psychological intervention for PTSD and SUD or PTSD only vs control intervention | RR 1.13 [0.88, 1.45] | 2 studies · 381 participants | Low Downgraded: risk of bias, inconsistency |
Non‐trauma‐focused psychological intervention for PTSD and SUD or PTSD only compared to active psychological intervention for SUD only
Population: Individuals with post‐traumatic stress disorder and comorbid substance use disorder
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
PTSD severity following treatment completion As assessed by the CAPS. High scores indicate greater symptom severity Non‐trauma‐focused psychological intervention for PTSD and SUD or PTSD only vs active psychological intervention | no estimate extracted | 2 studies · 128 participants | Very low Downgraded: risk of bias, imprecision, inconsistency |
Drug or alcohol use, or both following treatment completion As assessed by the SUI or ASI. High scores indicate greater symptom severity Non‐trauma‐focused psychological intervention for PTSD and SUD or PTSD only vs active psychological intervention | no estimate extracted | 2 studies · 128 participants | Low Downgraded: risk of bias, imprecision |
Treatment completers Non‐trauma‐focused psychological intervention for PTSD and SUD or PTSD only vs active psychological intervention | RR 0.91 [0.68, 1.2] | 2 studies · 128 participants | Very low Downgraded: risk of bias, imprecision |