Cochrane · systematic review · CD010828
Azapirones versus placebo for panic disorder in adults
Imai, H, Tajika, A, Chen, P, et al. · Cochrane Database of Systematic Reviews · 2014 · Cochrane Library
Common Mental DisordersAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
5
current version
GRADE rated
4
No studies
1
Included studies
NR
No studies 1 · 20%Ungraded 0 · 0%Very low 0 · 0%Low 3 · 60%Moderate 1 · 20%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Azapirone compared to placebo for panic disorder in adults
Population: adults with panic disorder
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Rate of 'response' Azapirone vs placebo | no estimate extracted | NR | No studies |
Dropouts for any reason Azapirone vs placebo | RR 2.13 [1.11, 4.07] | 3 studies · 170 participants | Moderate Downgraded: imprecision |
General anxiety Hamilton rating scale for anxiety Azapirone vs placebo | no estimate extracted | 2 studies · 115 participants | Low Downgraded: risk of bias, imprecision |
Agoraphobia Phobia scale Azapirone vs placebo | no estimate extracted | 1 study · 52 participants | Low Downgraded: risk of bias, imprecision |
Depression Hamilton rating scale for depression Azapirone vs placebo | no estimate extracted | 1 study · 52 participants | Low Downgraded: risk of bias, imprecision |