Cochrane · systematic review · CD011004
Psychological therapies for panic disorder with or without agoraphobia in adults: a network meta‐analysis
Pompoli, A, Furukawa, TA, Imai, H, et al. · Cochrane Database of Systematic Reviews · 2016 · Cochrane Library
Common Mental DisordersAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
20
current version
GRADE rated
19
No studies
1
Included studies
NR
No studies 1 · 5%Ungraded 0 · 0%Very low 9 · 45%Low 10 · 50%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Cognitive behaviour therapy compared to no treatment for panic disorder with or without agoraphobia in adults
Population: adult patients with panic disorder with or without agoraphobia
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Short‐term remission ( Cognitive behaviour therapy vs no treatment | OR 2.78 [0.54, 14.29] | 2 studies · 357 participants | Very low Downgraded: risk of bias, imprecision, indirectness |
Short‐term response ( Cognitive behaviour therapy vs no treatment | OR 7.14 [1.25, 50] | 2 studies · 357 participants | Very low Downgraded: risk of bias, imprecision, indirectness |
Short‐term dropouts ( Cognitive behaviour therapy vs no treatment | OR 6.25 [0.26, 100] | 4 studies · 278 participants | Very low Downgraded: risk of bias, imprecision, indirectness |
Long‐term remission/response ( Cognitive behaviour therapy vs no treatment | no estimate extracted | NR | No studies |
Short‐term improvement as measured on a continuous scale ( Cognitive behaviour therapy vs no treatment | no estimate extracted | 1 study · 27 participants | Low Downgraded: risk of bias, imprecision, indirectness |
Cognitive behaviour therapy compared to supportive psychotherapy for panic disorder with or without agoraphobia in adults
Population: adult patients with panic disorder with or without agoraphobia
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Short‐term remission ( Cognitive behaviour therapy vs supportive psychotherapy | OR 0.67 [0.25, 1.82] | 3 studies · 176 participants | Low Downgraded: risk of bias, imprecision, inconsistency, indirectness |
Short‐term response ( Cognitive behaviour therapy vs supportive psychotherapy | OR 1.12 [0.4, 3.26] | 3 studies · 176 participants | Very low Downgraded: risk of bias, imprecision, inconsistency, indirectness |
Short‐term dropouts ( Cognitive behaviour therapy vs supportive psychotherapy | OR 0.64 [0.28, 1.43] | 3 studies · 176 participants | Very low Downgraded: risk of bias, imprecision, inconsistency, indirectness |
Long‐term remission/response ( Cognitive behaviour therapy vs supportive psychotherapy | OR 2.09 [0.73, 5.98] | 1 study · 80 participants | Low Downgraded: risk of bias, imprecision, inconsistency, indirectness |
Short‐term improvement as measured on a continuous scale ( Cognitive behaviour therapy vs supportive psychotherapy | no estimate extracted | 3 studies · 152 participants | Low Downgraded: risk of bias, imprecision, inconsistency, indirectness |
Cognitive behaviour therapy compared to psychodynamic psychotherapy for panic disorder with or without agoraphobia in adults
Population: adult patients with panic disorder with or without agoraphobia
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Short‐term remission ( Cognitive behaviour therapy vs psychodynamic psychotherapy | OR 0.94 [0.27, 3.45] | 1 study · 54 participants | Very low Downgraded: risk of bias, imprecision, inconsistency, indirectness |
Short‐term response ( Cognitive behaviour therapy vs psychodynamic psychotherapy | OR 1.05 [0.28, 4] | 1 study · 54 participants | Very low Downgraded: risk of bias, imprecision, inconsistency, indirectness |
Short‐term dropouts ( Cognitive behaviour therapy vs psychodynamic psychotherapy | OR 1.92 [0.56, 6.67] | 1 study · 54 participants | Very low Downgraded: risk of bias, imprecision, inconsistency, indirectness |
Long‐term remission/response ( Cognitive behaviour therapy vs psychodynamic psychotherapy | OR 1.25 [0.37, 4.17] | 1 study · 54 participants | Low Downgraded: risk of bias, imprecision, inconsistency, indirectness |
Short‐term improvement as measured on a continuous scale ( Cognitive behaviour therapy vs psychodynamic psychotherapy | no estimate extracted | 1 study · 54 participants | Very low Downgraded: risk of bias, imprecision, inconsistency, indirectness |
Network meta‐analysis rankings of psychological therapies for panic disorder with or without agoraphobia in adults
Population: adult patients with panic disorder with or without agoraphobia
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Short‐term remission ( | no estimate extracted | 40 studies · 2491 participants | Low Downgraded: risk of bias |
Short‐term response ( | no estimate extracted | 37 studies · 2240 participants | Low Downgraded: risk of bias |
Short‐term dropouts ( | no estimate extracted | 47 studies · 2535 participants | Low Downgraded: risk of bias |
Long‐term remission/response ( | no estimate extracted | 9 studies · 464 participants | Low Downgraded: risk of bias |
Short‐term improvement as measured on a continuous scale ( | no estimate extracted | 57 studies · 2318 participants | Low Downgraded: risk of bias |