Cochrane · systematic review · CD009083

Repetitive transcranial magnetic stimulation (rTMS) for panic disorder in adults

Li, H, Wang, J, Li, C, et al. · Cochrane Database of Systematic Reviews · 2014 · Cochrane Library

Common Mental DisordersAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
6
current version
GRADE rated
3
No studies
3
Included studies
NR
No studies 3 · 50%Ungraded 0 · 0%Very low 3 · 50%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

rTMS + pharmacotherapy versus sham rTMS + pharmacotherapy for panic disorder

Population: participants with panic disorder
6 questions
OutcomeEffectEvidenceStatus / GRADE
Reduction of panic symptoms: Panic Disorder Severity Scale (PDSS) (high=poor, data skewed) PDSS, Scale from: 0 to 28)
rTMS + pharmacotherapy vs sham rTMS + pharmacotherapy
no estimate extractedNRNo studies
Acceptability: dropouts for any reason number of dropouts
rTMS + pharmacotherapy vs sham rTMS + pharmacotherapy
no estimate extracted2 studies · 40 participantsVery low
Downgraded: risk of bias, imprecision
Acceptability: dropouts for adverse effects number of dropouts
rTMS + pharmacotherapy vs sham rTMS + pharmacotherapy
RD 02 studies · 40 participantsVery low
Downgraded: risk of bias, imprecision
Improvment of social function: Self‐reported social adaptation scale (SASS) (low=poor), acute effect SASS. Scale from: 0 to 60.
rTMS + pharmacotherapy vs sham rTMS + pharmacotherapy
no estimate extracted1 study · 21 participantsVery low
Downgraded: risk of bias, imprecision
Quality of life (such as the SF‐36 Health Survey (Ware 1992)
rTMS + pharmacotherapy vs sham rTMS + pharmacotherapy
no estimate extractedNRNo studies
Safety of rTMS: Frequency of rTMS side effects (values are percentages) self‐reported questionnaire
rTMS + pharmacotherapy vs sham rTMS + pharmacotherapy
no estimate extractedNRNo studies