Cochrane Review Group

Breast Cancer

49 systematic reviews in Breast Cancer ask 487 questions. 9% have no studies to answer them, 22.2% rest on very low certainty evidence and 39.7% reach moderate or high certainty.

Reviews

Questions

487

current versions

No studies

Moderate or high

39.7%

No studies 44 · 9%Ungraded 14 · 2.9%Very low 108 · 22.2%Low 128 · 26.3%Moderate 107 · 22%High 86 · 17.7%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Search questions in Breast Cancer

Thinnest evidence

All no studies and very low questions

Question	Effect	Evidence	Status / GRADE
Shared decision‐making (all components) vs control Satisfaction with the decision‐making process · women aged 40 to 75 years at average to moderate risk of breast cancer Shared decision‐making for supporting women’s decisions about breast cancer screening (2024) · Cochrane	no estimate extracted	NR	No studies
Some components of shared decision‐making, including clarification of values and preferences, vs control Adherence to the chosen option · women aged 38 to 71 years at average to moderate risk of breast cancer Shared decision‐making for supporting women’s decisions about breast cancer screening (2024) · Cochrane	no estimate extracted	NR	No studies
Some components of shared decision‐making, including clarification of values and preferences, vs control Choice of an option aligned with each woman’s values and preferences · women aged 38 to 71 years at average to moderate risk of breast cancer Shared decision‐making for supporting women’s decisions about breast cancer screening (2024) · Cochrane	no estimate extracted	NR	No studies
Some components of shared decision‐making, including clarification of values and preferences, vs control Woman's involvement · women aged 38 to 71 years at average to moderate risk of breast cancer Shared decision‐making for supporting women’s decisions about breast cancer screening (2024) · Cochrane	no estimate extracted	NR	No studies
Studies focused only on enhanced communication, without clarification of values and preferences, vs control Satisfaction with the decision‐making process · women aged 40 to 75 years old at average to moderate risk of breast cancer Shared decision‐making for supporting women’s decisions about breast cancer screening (2024) · Cochrane	no estimate extracted	NR	No studies
Studies focused only on enhanced communication, without clarification of values and preferences, vs control Adherence to the chosen option · women aged 40 to 75 years old at average to moderate risk of breast cancer Shared decision‐making for supporting women’s decisions about breast cancer screening (2024) · Cochrane	no estimate extracted	NR	No studies
Studies focused only on enhanced communication, without clarification of values and preferences, vs control Choice of an option aligned with each woman’s values and preferences · women aged 40 to 75 years old at average to moderate risk of breast cancer Shared decision‐making for supporting women’s decisions about breast cancer screening (2024) · Cochrane	no estimate extracted	NR	No studies
Shared decision‐making (all components) vs control Confidence in the decision made · women aged 40 to 75 years at average to moderate risk of breast cancer Shared decision‐making for supporting women’s decisions about breast cancer screening (2024) · Cochrane	no estimate extracted	NR	No studies
Studies focused only on enhanced communication, without clarification of values and preferences, vs control Woman's involvement · women aged 40 to 75 years old at average to moderate risk of breast cancer Shared decision‐making for supporting women’s decisions about breast cancer screening (2024) · Cochrane	no estimate extracted	NR	No studies
Shared decision‐making (all components) vs control Knowledge of all the options · women aged 40 to 75 years at average to moderate risk of breast cancer Shared decision‐making for supporting women’s decisions about breast cancer screening (2024) · Cochrane	RR 1.18 [0.61, 2.28]	1 study · 133 participants	Very low
Shared decision‐making (all components) vs control Adherence to the chosen option · women aged 40 to 75 years at average to moderate risk of breast cancer Shared decision‐making for supporting women’s decisions about breast cancer screening (2024) · Cochrane	no estimate extracted	NR	No studies
Shared decision‐making (all components) vs control Choice of an option aligned with each woman’s values and preferences · women aged 40 to 75 years at average to moderate risk of breast cancer Shared decision‐making for supporting women’s decisions about breast cancer screening (2024) · Cochrane	no estimate extracted	NR	No studies

Reviews 49

Shared decision‐making for supporting women’s decisions about breast cancer screening

Riganti, P, Ruiz Yanzi, MV, et al. · Cochrane Database of Systematic Reviews · 2024

Breast Cancer

Thinnest evidence

Reviews 49

Shared decision‐making for supporting women’s decisions about breast cancer screening

Psychological interventions for women with non‐metastatic breast cancer

Mammography in combination with breast ultrasonography versus mammography for breast cancer screening in women at average risk

Skin‐sparing mastectomy for the treatment of breast cancer

Training health workers in clinical breast examination for early detection of breast cancer in low‐ and middle‐income countries

Post‐mastectomy radiotherapy for women with early breast cancer and one to three positive lymph nodes

Platinum‐based chemotherapy for early triple‐negative breast cancer

Systemic therapies for preventing or treating aromatase inhibitor‐induced musculoskeletal symptoms in early breast cancer

Specialist breast care nurses for support of women with breast cancer

Partial breast irradiation versus whole breast radiotherapy for early breast cancer

Capecitabine for hormone receptor‐positive versus hormone receptor‐negative breast cancer

PARP (Poly ADP‐Ribose Polymerase) inhibitors for locally advanced or metastatic breast cancer

Paravertebral anaesthesia with or without sedation versus general anaesthesia for women undergoing breast cancer surgery

Mammographic density, endocrine therapy and breast cancer risk: a prognostic and predictive biomarker review

Perioperative systemic nonsteroidal anti‐inflammatory drugs (NSAIDs) in women undergoing breast surgery

Oncoplastic breast‐conserving surgery for women with primary breast cancer

Body weight management in overweight and obese breast cancer survivors

Exercise therapies for preventing or treating aromatase inhibitor‐induced musculoskeletal symptoms in early breast cancer

Indocyanine green angiography for preventing postoperative mastectomy skin flap necrosis in immediate breast reconstruction

Ovarian suppression for adjuvant treatment of hormone receptor‐positive early breast cancer

Platinum‐containing regimens for triple‐negative metastatic breast cancer

Taxanes for adjuvant treatment of early breast cancer

Surgical interventions for the prevention or treatment of lymphoedema after breast cancer treatment

Mindfulness‐based stress reduction for women diagnosed with breast cancer

Risk‐reducing medications for primary breast cancer: a network meta‐analysis