Cochrane · systematic review · CD012110
Body weight management in overweight and obese breast cancer survivors
Shaikh, H, Bradhurst, P, Ma, LX, et al. · Cochrane Database of Systematic Reviews · 2020 · Cochrane Library
Breast CancerAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
16
current version
GRADE rated
9
No studies
7
Included studies
NR
No studies 7 · 43.8%Ungraded 0 · 0%Very low 0 · 0%Low 8 · 50%Moderate 0 · 0%High 1 · 6.3%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
All weight loss interventions for overweight and obese breast cancer survivors
Population: overweight and obese breast cancer survivors
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Overall survival | no estimate extracted | NR | No studies |
Breast cancer recurrence | RR 1.95 [0.68, 5.6] | 4 studies · 281 participants | Low Downgraded: imprecision |
Change in body weight | no estimate extracted | 21 studies · 1751 participants | Low Downgraded: risk of bias, inconsistency |
Change in BMI | no estimate extracted | 17 studies · 1353 participants | Low Downgraded: risk of bias, inconsistency |
Change in waist circumference | no estimate extracted | 13 studies · 1193 participants | Low Downgraded: risk of bias, inconsistency |
Disease‐free survival | no estimate extracted | NR | No studies |
Adverse events | RR 0.94 [0.76, 1.17] | 4 studies · 394 participants | High |
Change in quality of life ‐ overall scales | no estimate extracted | 10 studies · 867 participants | Low Downgraded: risk of bias, inconsistency |
Weight loss interventions involving diet, exercise and psychosocial support for overweight and obese breast cancer survivors
Population: overweight and obese breast cancer survivors
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Overall survival | no estimate extracted | NR | No studies |
Breast cancer recurrence | no estimate extracted | NR | No studies |
Change in body weight | no estimate extracted | 13 studies · 1526 participants | Low Downgraded: risk of bias, inconsistency |
Change in BMI | no estimate extracted | 11 studies · 1187 participants | Low Downgraded: risk of bias, inconsistency |
Change in waist circumference | no estimate extracted | 8 studies · 1021 participants | Low Downgraded: risk of bias, inconsistency |
Disease‐free survival ‐ not reported | no estimate extracted | NR | No studies |
Adverse events | no estimate extracted | NR | No studies |
Change in quality of life ‐ overall scales | no estimate extracted | NR | No studies |