Cochrane · systematic review · CD011433

Surgical interventions for the prevention or treatment of lymphoedema after breast cancer treatment

Markkula, SP, Leung, N, Allen, VB, et al. · Cochrane Database of Systematic Reviews · 2019 · Cochrane Library

Breast CancerAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
6
current version
GRADE rated
6
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 5 · 83.3%Low 1 · 16.7%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Lymphaticovenular anastomosis compared to standard care for prevention of lymphoedema development

Population: prevention of lymphoedema development
1 question
OutcomeEffectEvidenceStatus / GRADE
Development of LE
Lymphaticovenular anastomosis vs standard care
RR 0.2 [0.06, 0.63]2 studies · 95 participantsLow

Vascularised lymph node transfer compared to standard care for treatment of arm lymphoedema

Population: treatment of arm lymphoedema
5 questions
OutcomeEffectEvidenceStatus / GRADE
Reduction of LE (%)
Vascularised lymph node transfer vs standard care
MD 391 study · 36 participantsVery low
Downgraded: risk of bias, imprecision, indirectness
Number of infections per year
Vascularised lymph node transfer vs standard care
MD 1.221 study · 36 participantsVery low
Downgraded: risk of bias, indirectness
Pain score (1‐10; where 1 = no pain; 10 = extreme pain)
Vascularised lymph node transfer vs standard care
MD 4.161 study · 36 participantsVery low
Downgraded: risk of bias, imprecision, indirectness
Heaviness score (1‐10; where 1 = no heaviness; 10 = extreme heaviness)
Vascularised lymph node transfer vs standard care
MD 4.271 study · 36 participantsVery low
Downgraded: risk of bias, imprecision, indirectness
Function score (1‐10; where 1 = good function; 10 = poor function)
Vascularised lymph node transfer vs standard care
MD 3.771 study · 36 participantsVery low
Downgraded: risk of bias, imprecision, indirectness