Cochrane · systematic review · CD012968
Paravertebral anaesthesia with or without sedation versus general anaesthesia for women undergoing breast cancer surgery
Chhabra, A, Roy Chowdhury, A, Prabhakar, H, et al. · Cochrane Database of Systematic Reviews · 2021 · Cochrane Library
Breast CancerAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
6
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 1 · 14.3%Very low 0 · 0%Low 4 · 57.1%Moderate 2 · 28.6%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Paravertebral anaesthesia with or without sedation compared to general anaesthesia for women undergoing breast cancer surgery
Population: women undergoing breast cancer surgery
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Postoperative analgesic requirement Paravertebral anaesthesia with or without sedation vs general anaesthesia | OR 0.07 [0.01, 0.34] | 5 studies · 305 participants | Low Downgraded: risk of bias, imprecision |
Postoperative nausea and vomiting (PONV) Paravertebral anaesthesia with or without sedation vs general anaesthesia | OR 0.16 [0.08, 0.3] | 6 studies · 323 participants | Moderate Downgraded: risk of bias, imprecision, inconsistency |
Postoperative pain at 2 hours Paravertebral anaesthesia with or without sedation vs general anaesthesia | no estimate extracted | 4 studies · 224 participants | Moderate Downgraded: risk of bias, imprecision, inconsistency |
Postoperative pain at 24 hours on rest Paravertebral anaesthesia with or without sedation vs general anaesthesia | no estimate extracted | 3 studies · 169 participants | Low Downgraded: risk of bias, imprecision, inconsistency |
Postoperative pain at 6 hours on movement Paravertebral anaesthesia with or without sedation vs general anaesthesia | no estimate extracted | 2 studies · 130 participants | Low Downgraded: risk of bias, imprecision, inconsistency |
Postoperative pain at 24 hours on movement Paravertebral anaesthesia with or without sedation vs general anaesthesia | no estimate extracted | 2 studies · 130 participants | Low Downgraded: risk of bias, imprecision, inconsistency |
Mortality Paravertebral anaesthesia with or without sedation vs general anaesthesia | no estimate extracted | 9 studies · 9 participants | Ungraded |