Cochrane · systematic review · CD012515

Training health workers in clinical breast examination for early detection of breast cancer in low‐ and middle‐income countries

Sayed, S, Ngugi, AK, Nwosu, N, et al. · Cochrane Database of Systematic Reviews · 2023 · Cochrane Library

Breast CancerAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
6
current version
GRADE rated
6
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 2 · 33.3%Low 2 · 33.3%Moderate 2 · 33.3%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Summary of findings table 1

Population: health workers
6 questions
OutcomeEffectEvidenceStatus / GRADE
Breast cancer stage at the time of presentation: defined as the proportion of women with breast cancer diagnosed at early stage (stage 0, I, II) Time of outcome assessment: 3 years to 20 years Method of measurement: CBE
RR 1.44 [1.01, 2.06]3 studies · 593 participantsLow
Downgraded: risk of bias, imprecision
Breast cancer stage at the time of presentation: defined as the proportion of women with breast cancer diagnosed at late stage (stage III, IV) Time of outcome assessment: 3 years to 20 years Method of measurement: CBE
RR 0.58 [0.36, 0.94]3 studies · 593 participantsLow
Downgraded: risk of bias, imprecision
Accuracy of health worker‐performed CBE Time of outcome assessment: 2 years to 20 years Method of measurement: Sensitivity, specificity and positive predictive value
no estimate extracted2 studies · 2 participantsVery low
Downgraded: risk of bias, inconsistency, indirectness
CBE coverage Time of outcome assessment: 20 years Method of measurement: active surveillance
no estimate extracted1 study · 1 participantsModerate
Downgraded: risk of bias
Completion of
no estimate extracted1 study · 1 participantsModerate
Downgraded: risk of bias
Breast cancer mortality: defined as deaths among women who received a diagnosis of breast cancer Time of outcome assessment: 3 years to 20 years Method of measurement: death registration offices, hospital records, and house visits
RR 0.88 [0.24, 3.26]2 studies · 355 participantsVery low
Downgraded: risk of bias, inconsistency