Cochrane · systematic review · CD013280
Indocyanine green angiography for preventing postoperative mastectomy skin flap necrosis in immediate breast reconstruction
Pruimboom, T, Schols, RM, Van Kuijk, SMJ, et al. · Cochrane Database of Systematic Reviews · 2020 · Cochrane Library
Breast CancerAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
12
current version
GRADE rated
11
No studies
1
Included studies
NR
No studies 1 · 8.3%Ungraded 0 · 0%Very low 11 · 91.7%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Indocyanine Green Angiography (ICGA) compared to clinical evaluation for preventing complications (on a per patient basis) in immediate breast reconstruction following mastectomy.
Population: women undergoing immediate breast reconstruction following mastectomy
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Mastectomy skin flap necrosis (number of women with mastectomy skin flap necrosis within 30 days after surgery) Indocyanine Green Angiography (ICGA) vs clinical evaluation | RR 0.79 [0.4, 1.56] | 3 studies · 573 participants | Very low Downgraded: imprecision |
Reoperation (number of women that were operated again within 30 days after surgery) Indocyanine Green Angiography (ICGA) vs clinical evaluation | RR 0.5 [0.35, 0.72] | 4 studies · 613 participants | Very low Downgraded: imprecision |
Dehiscence (number of women with dehiscence within 30 days after surgery). Indocyanine Green Angiography (ICGA) vs clinical evaluation | RR 4 [0.45, 35.45] | 1 study · 368 participants | Very low Downgraded: imprecision |
Infection (number of women with infection of the skin flap or implant within 30 days after surgery) Indocyanine Green Angiography (ICGA) vs clinical evaluation | RR 0.91 [0.6, 1.4] | 4 studies · 613 participants | Very low Downgraded: imprecision |
Haematoma (number of women with haematoma within 30 days after surgery) Indocyanine Green Angiography (ICGA) vs clinical evaluation | RR 0.87 [0.3, 2.53] | 2 studies · 459 participants | Very low Downgraded: imprecision |
Seroma (number of women with seroma within 30 days after surgery) Indocyanine Green Angiography (ICGA) vs clinical evaluation | RR 1.68 [0.41, 6.8] | 2 studies · 408 participants | Very low Downgraded: imprecision |
Indocyanine Green Angiography (ICGA) compared to clinical evaluation for preventing complications (on a per breast basis) in immediate breast reconstruction following mastectomy.
Population: women undergoing immediate breast reconstruction following mastectomy
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Mastectomy skin flap necrosis (number of breasts with mastectomy skin flap necrosis within 30 days after surgery) Indocyanine Green Angiography (ICGA) vs clinical evaluation | RR 0.62 [0.48, 0.82] | NR | Very low Downgraded: imprecision |
Reoperation (number of breasts that needed to be operated again within 30 days after surgery) Indocyanine Green Angiography (ICGA) vs clinical evaluation | RR 0.65 [0.47, 0.92] | NR | Very low Downgraded: imprecision |
Dehiscence ‐ not reported Indocyanine Green Angiography (ICGA) vs clinical evaluation | no estimate extracted | NR | No studies |
Infection (number of breasts with infection within 30 days after surgery) Indocyanine Green Angiography (ICGA) vs clinical evaluation | RR 0.65 [0.44, 0.97] | NR | Very low Downgraded: imprecision |
Haematoma (number of breasts with haematoma within 30 days after surgery) Indocyanine Green Angiography (ICGA) vs clinical evaluation | RR 1.53 [0.47, 4.95] | NR | Very low Downgraded: imprecision |
Seroma (number of breast with seroma within 30 days after surgery) Indocyanine Green Angiography (ICGA) vs clinical evaluation | RR 0.71 [0.37, 1.35] | NR | Very low Downgraded: imprecision |