Cochrane · systematic review · CD014463
Post‐mastectomy radiotherapy for women with early breast cancer and one to three positive lymph nodes
Verma, R, Chandarana, M, Barrett, J, et al. · Cochrane Database of Systematic Reviews · 2023 · Cochrane Library
Breast CancerAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
2
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 5 · 71.4%Very low 0 · 0%Low 1 · 14.3%Moderate 1 · 14.3%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Summary of findings table ‐ Postmastectomy radiotherapy (PMRT) compared to no PMRT in women with breast cancer and one to three positive lymph nodes
Population: women with breast cancer and one to three positive lymph nodes
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Local and regional recurrence (LRR) Summary of findings table ‐ Postmastectomy radiotherapy (PMRT) vs no PMRT | HR 0.2 [0.13, 0.33] | 1 study · 552 participants | Low Downgraded: risk of bias, imprecision |
Overall survival (OS) Summary of findings table ‐ Postmastectomy radiotherapy (PMRT) vs no PMRT | HR 0.76 [0.6, 0.97] | 1 study · 552 participants | Moderate Downgraded: risk of bias |
Disease‐free survival (DFS) Summary of findings table ‐ Postmastectomy radiotherapy (PMRT) vs no PMRT | no estimate extracted | 0 studies · 0 participants | Ungraded |
Time to progression Summary of findings table ‐ Postmastectomy radiotherapy (PMRT) vs no PMRT | no estimate extracted | 0 studies · 0 participants | Ungraded |
Short‐term adverse events Summary of findings table ‐ Postmastectomy radiotherapy (PMRT) vs no PMRT | no estimate extracted | 0 studies · 0 participants | Ungraded |
Long‐term adverse events Summary of findings table ‐ Postmastectomy radiotherapy (PMRT) vs no PMRT | no estimate extracted | 0 studies · 0 participants | Ungraded |
Quality of life (QoL) Summary of findings table ‐ Postmastectomy radiotherapy (PMRT) vs no PMRT | no estimate extracted | 0 studies · 0 participants | Ungraded |