Cochrane · systematic review · CD012988
Exercise therapies for preventing or treating aromatase inhibitor‐induced musculoskeletal symptoms in early breast cancer
Roberts, KE, Rickett, K, Feng, S, et al. · Cochrane Database of Systematic Reviews · 2020 · Cochrane Library
Breast CancerAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
7
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 5 · 71.4%Low 2 · 28.6%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Exercise therapies compared to standard care for the management of aromatase inhibitor‐induced musculoskeletal symptoms
Population: women with aromatase inhibitor‐induced musculoskeletal symptoms (AIMSS)
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Overall change in worst pain scores Exercise therapies vs standard care | no estimate extracted | 4 studies · 284 participants | Very low Downgraded: risk of bias, imprecision, inconsistency, publication bias |
Overall change in stiffness scores Exercise therapies vs standard care | no estimate extracted | 1 study · 53 participants | Low Downgraded: risk of bias, imprecision |
Overall change in grip strength Exercise therapies vs standard care | no estimate extracted | 1 study · 83 participants | Very low Downgraded: risk of bias, imprecision, publication bias |
Overall change in health‐related quality of life Exercise therapies vs standard care | no estimate extracted | 2 studies · 123 participants | Very low Downgraded: risk of bias, imprecision, publication bias |
Overall change in cancer‐specific quality of life Exercise therapies vs standard care | no estimate extracted | 2 studies · 136 participants | Very low Downgraded: risk of bias, imprecision, publication bias |
Adverse effects secondary to the intervention Exercise therapies vs standard care | no estimate extracted | 4 studies · 331 participants | Low Downgraded: risk of bias, imprecision |
Adherence to aromatase inhibitors Exercise therapies vs standard care | OR 2.43 [0.41, 14.63] | 2 studies · 224 participants | Very low Downgraded: risk of bias, imprecision, publication bias |