Cochrane Review Group

Eyes and Vision

171 systematic reviews in Eyes and Vision ask 2,112 questions. 27.8% have no studies to answer them, 21.1% rest on very low certainty evidence and 20.2% reach moderate or high certainty.

Reviews
171
Questions
2,112
current versions
No studies
27.8%
Moderate or high
20.2%
No studies 587 · 27.8%Ungraded 95 · 4.5%Very low 446 · 21.1%Low 557 · 26.4%Moderate 361 · 17.1%High 66 · 3.1%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
LipiFlow vs basic warm compresses
Mean change from baseline in symptom scores at 1 to 4 weeks (lower is favored) · people with dry eye
LipiFlow for the treatment of dry eye disease (2024) · Cochrane
no estimate extractedNRVery low
LipiFlow vs thermostatic devices
Proportion of participants with intervention‐related, vision‐threatening adverse events at 1 to 4 weeks · people with dry eye
LipiFlow for the treatment of dry eye disease (2024) · Cochrane
no estimate extracted4 studies · 445 participantsVery low
LipiFlow vs basic warm compresses
Mean change from baseline in meibomian gland expression scores at 1 to 4 weeks (higher is favored) · people with dry eye
LipiFlow for the treatment of dry eye disease (2024) · Cochrane
SMD 1.312 studies · 76 participantsVery low
LipiFlow vs basic warm compresses
Mean change from baseline in meibum quality scores at 1 to 4 weeks (higher is favored) · people with dry eye
LipiFlow for the treatment of dry eye disease (2024) · Cochrane
no estimate extracted1 study · 46 participantsVery low
LipiFlow vs thermostatic devices
Mean change from baseline in symptom scores at 1 to 4 weeks (lower is favored) · people with dry eye
LipiFlow for the treatment of dry eye disease (2024) · Cochrane
no estimate extractedNRVery low
Face‐down positioning vs other positioning
Proportion of eyes with retinal displacement at 6 months or later (RR < 1 favored) · people with primary macula‐involving rhegmatogenous retinal detachments
Face‐down positioning or posturing after pars plana vitrectomy for macula‐involving rhegmatogenous retinal… (2024) · Cochrane
RR 0.73 [0.54, 0.99]1 study · 239 participantsVery low
Face‐down positioning vs other positioning
Mean change in logMAR or Snellen visual acuity from baseline to 3 months or later (lower is favored) · people with primary macula‐involving rhegmatogenous retinal detachments
Face‐down positioning or posturing after pars plana vitrectomy for macula‐involving rhegmatogenous retinal… (2024) · Cochrane
no estimate extracted1 study · 56 participantsVery low
Face‐down positioning vs other positioning
Mean objective distortion score at 3 months or later (lower is favored) · people with primary macula‐involving rhegmatogenous retinal detachments
Face‐down positioning or posturing after pars plana vitrectomy for macula‐involving rhegmatogenous retinal… (2024) · Cochrane
MD 1.81 study · 219 participantsVery low
Face‐down positioning vs other positioning
Quality of life assessments at 3 months or later (higher is favored) · people with primary macula‐involving rhegmatogenous retinal detachments
Face‐down positioning or posturing after pars plana vitrectomy for macula‐involving rhegmatogenous retinal… (2024) · Cochrane
no estimate extracted1 study · 217 participantsVery low
Face‐down positioning vs other positioning
Frequency of intervention‐related ocular adverse events ( · people with primary macula‐involving rhegmatogenous retinal detachments
Face‐down positioning or posturing after pars plana vitrectomy for macula‐involving rhegmatogenous retinal… (2024) · Cochrane
no estimate extracted1 study · 262 participantsVery low
Face‐down positioning vs other positioning
Frequency of intervention‐related non‐ocular adverse events ( · people with primary macula‐involving rhegmatogenous retinal detachments
Face‐down positioning or posturing after pars plana vitrectomy for macula‐involving rhegmatogenous retinal… (2024) · Cochrane
no estimate extractedNRNo studies
Lutein with or without zeaxanthin vs placebo
Adverse effects · people with AMD
Antioxidant vitamin and mineral supplements for slowing the progression of age‐related macular degeneration (2023) · Cochrane
OR 1.06NRVery low

Reviews 171

Interventions to improve access to cataract surgical services and their impact on equity in low‐ and middle‐income countries

Ramke, J, Petkovic, J, et al. · Cochrane Database of Systematic Reviews · 2017
CochraneSoF table
14 questions

Ocriplasmin for symptomatic vitreomacular adhesion

Neffendorf, JE, Kirthi, V, et al. · Cochrane Database of Systematic Reviews · 2017
CochraneSoF table
7 questions

Topical treatments for blepharokeratoconjunctivitis in children

O'Gallagher, M, Bunce, C, et al. · Cochrane Database of Systematic Reviews · 2017
CochraneSoF table
7 questions

Surgical interventions for vertical strabismus in superior oblique palsy

Chang, MY, Coleman, AL, et al. · Cochrane Database of Systematic Reviews · 2017
CochraneSoF table
14 questions

Antibiotics versus no treatment for toxoplasma retinochoroiditis

Pradhan, E, Bhandari, S, et al. · Cochrane Database of Systematic Reviews · 2016
CochraneSoF table
5 questions

Multifocal versus monofocal intraocular lenses after cataract extraction

de Silva, SR, Evans, JR, et al. · Cochrane Database of Systematic Reviews · 2016
CochraneSoF table
7 questions

Patching for corneal abrasion

Lim, CHL, Turner, A, et al. · Cochrane Database of Systematic Reviews · 2016
CochraneSoF table
8 questions

Prophylactic non‐steroidal anti‐inflammatory drugs for the prevention of macular oedema after cataract surgery

Lim, BX, Lim, CHL, et al. · Cochrane Database of Systematic Reviews · 2016
CochraneSoF table
14 questions

Statins for age‐related macular degeneration

Gehlbach, P, Li, T, et al. · Cochrane Database of Systematic Reviews · 2016
CochraneSoF table
3 questions

Oral antivirals for preventing recurrent herpes simplex keratitis in people with corneal grafts

Bhatt, UK, Abdul Karim, MN, et al. · Cochrane Database of Systematic Reviews · 2016
CochraneSoF table
4 questions

Over the counter (OTC) artificial tear drops for dry eye syndrome

Pucker, AD, Ng, SM, et al. · Cochrane Database of Systematic Reviews · 2016
CochraneSoF table
31 questions

Anti‐vascular endothelial growth factor for control of wound healing in glaucoma surgery

Cheng, JW, Cheng, SW, et al. · Cochrane Database of Systematic Reviews · 2016
CochraneSoF table
7 questions

Laser‐assisted subepithelial keratectomy (LASEK) versus photorefractive keratectomy (PRK) for correction of myopia

Li, SM, Zhan, S, et al. · Cochrane Database of Systematic Reviews · 2016
CochraneSoF table
6 questions

Integrated versus non‐integrated orbital implants for treating anophthalmic sockets

Schellini, S, El Dib, R, et al. · Cochrane Database of Systematic Reviews · 2016
CochraneSoF table
4 questions

Doxycycline plus ivermectin versus ivermectin alone for treatment of patients with onchocerciasis

Abegunde, AT, Ahuja, RM, et al. · Cochrane Database of Systematic Reviews · 2016
CochraneSoF table
6 questions

Anti‐vascular endothelial growth factor for choroidal neovascularisation in people with pathological myopia

Zhu, Y, Zhang, T, et al. · Cochrane Database of Systematic Reviews · 2016
CochraneSoF table
7 questions

Fibrin glue versus sutures for conjunctival autografting in primary pterygium surgery

Romano, V, Cruciani, M, et al. · Cochrane Database of Systematic Reviews · 2016
CochraneSoF table
3 questions

Aflibercept for neovascular age‐related macular degeneration

Sarwar, S, Clearfield, E, et al. · Cochrane Database of Systematic Reviews · 2016
CochraneSoF table
6 questions

Conjunctival autograft for pterygium

Clearfield, E, Muthappan, V, et al. · Cochrane Database of Systematic Reviews · 2016
CochraneSoF table
7 questions

Valacyclovir versus acyclovir for the treatment of herpes zoster ophthalmicus in immunocompetent patients

Schuster, AK, Harder, BC, et al. · Cochrane Database of Systematic Reviews · 2016
CochraneSoF table
7 questions

Antiviral treatment and other therapeutic interventions for herpes simplex virus epithelial keratitis

Wilhelmus, KR · Cochrane Database of Systematic Reviews · 2015
CochraneSoF table
28 questions

Medical interventions for fungal keratitis

FlorCruz, NV, Evans, JR · Cochrane Database of Systematic Reviews · 2015
CochraneSoF table
6 questions

Mitomycin C versus 5‐Fluorouracil for wound healing in glaucoma surgery

Cabourne, E, Clarke, JCK, et al. · Cochrane Database of Systematic Reviews · 2015
CochraneSoF table
7 questions

Laser treatment of drusen to prevent progression to advanced age‐related macular degeneration

Virgili, G, Michelessi, M, et al. · Cochrane Database of Systematic Reviews · 2015
CochraneSoF table
7 questions

Combined surgery versus cataract surgery alone for eyes with cataract and glaucoma

Zhang, ML, Hirunyachote, P, et al. · Cochrane Database of Systematic Reviews · 2015
CochraneSoF table
5 questions