Cochrane · systematic review · CD007824

Oral antivirals for preventing recurrent herpes simplex keratitis in people with corneal grafts

Bhatt, UK, Abdul Karim, MN, Prydal, JI, et al. · Cochrane Database of Systematic Reviews · 2016 · Cochrane Library

Eyes and VisionAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
4
current version
GRADE rated
2
No studies
2
Included studies
NR
No studies 2 · 50%Ungraded 0 · 0%Very low 0 · 0%Low 2 · 50%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Comparison

Population: People with HED who had corneal graft(s)
4 questions
OutcomeEffectEvidenceStatus / GRADE
HSK recurrence in people with corneal graft
RR 0.29 [0.13, 0.64]3 studies · 126 participantsLow
Downgraded: risk of bias
Graft failure
RR 0.4 [0.16, 0.97]3 studies · 126 participantsLow
Downgraded: risk of bias
Adverse outcomes
no estimate extractedNRNo studies
Quality of life
no estimate extractedNRNo studies