Cochrane · systematic review · CD011965
Topical treatments for blepharokeratoconjunctivitis in children
O'Gallagher, M, Bunce, C, Hingorani, M, et al. · Cochrane Database of Systematic Reviews · 2017 · Cochrane Library
Eyes and VisionAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
4
No studies
3
Included studies
NR
No studies 3 · 42.9%Ungraded 0 · 0%Very low 4 · 57.1%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Comparison
Population: children with blepharokeratoconjunctivitis
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Improvement in symptoms, reported by the child or by their parents/carers, preferably measured by a validated tool, at three months (± one month) after start of treatment | no estimate extracted | 1 study · 137 participants | Very low |
Elimination of all clinical signs of ocular surface inflammation ('complete success'), preferably measured by a composite grading system, at three months (± one month) after start of treatment | no estimate extracted | NR | No studies |
Improvement of clinical signs of ocular surface inflammation ('partial success'), preferably measured by a composite grading system, at three months (± one month) after start of treatment | no estimate extracted | 137 participants | Very low |
Change from baseline in best corrected visual acuity in affected eye(s) in logMAR | no estimate extracted | 1 study · 137 participants | Very low |
Uncontrolled or poorly controlled disease progression due to treatment failure, at three months (± one month) after start of treatment | no estimate extracted | NR | No studies |
Adverse effects of medication, at any time during treatment | no estimate extracted | 1 study · 137 participants | Very low |
Quality of life | no estimate extracted | NR | No studies |