Cochrane · systematic review · CD004241

Medical interventions for fungal keratitis

FlorCruz, NV, Evans, JR · Cochrane Database of Systematic Reviews · 2015 · Cochrane Library

Eyes and VisionAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
6
current version
GRADE rated
4
No studies
2
Included studies
NR
No studies 2 · 33.3%Ungraded 0 · 0%Very low 0 · 0%Low 2 · 33.3%Moderate 0 · 0%High 2 · 33.3%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Comparison

Population: people with fungal ulcers
6 questions
OutcomeEffectEvidenceStatus / GRADE
Clnical cure at 2 to 3 months
RR 1.07 [0.89, 1.28]1 study · 30 participantsLow
Downgraded: risk of bias, imprecision, inconsistency
Best corrected visual acuity at 2 to 3 months (measured using logMAR scale. A score of 0 = good vision, higher score is worse vision)
no estimate extracted3 studies · 434 participantsLow
Downgraded: risk of bias, imprecision, inconsistency
Time to clinical cure
hazard ratio 1.25 [0.88, 1.15]2011 participantsHigh
Compliance with treatment
no estimate extractedNRNo studies
Corneal perforation or penetrating keratoplasty, or both, at 2 to 3 months
RR 0.61 [0.4, 0.94]3 studies · 434 participantsHigh
Quality of life
no estimate extractedNRNo studies