Cochrane · systematic review · CD002218

Antibiotics versus no treatment for toxoplasma retinochoroiditis

Pradhan, E, Bhandari, S, Gilbert, RE, et al. · Cochrane Database of Systematic Reviews · 2016 · Cochrane Library

Eyes and VisionAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
5
current version
GRADE rated
4
No studies
1
Included studies
NR
No studies 1 · 20%Ungraded 0 · 0%Very low 0 · 0%Low 3 · 60%Moderate 1 · 20%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Antibiotic versus no treatment for toxoplasma retinochoroiditis

Population: People with toxoplasma retinochoroiditis
5 questions
OutcomeEffectEvidenceStatus / GRADE
Change in visual acuity
Antibiotic vs no treatment
no estimate extracted1 study · 93 participantsLow
Downgraded: imprecision, indirectness
or more recurrences of retinochoroiditis
Antibiotic vs no treatment
RR 0.26 [0.11, 0.63]3 studies · 227 participantsModerate
Downgraded: risk of bias
Improvement in intraocular inflammation
Antibiotic vs no treatment
RR 1.76 [0.98, 3.19]1 study · 29 participantsLow
Downgraded: imprecision
Size of lesion
Antibiotic vs no treatment
no estimate extractedNRNo studies
Adverse events
Antibiotic vs no treatment
RR 3 [0.37, 24.17]1 study · 20 participantsLow
Downgraded: imprecision