Cochrane · systematic review · CD006683
Prophylactic non‐steroidal anti‐inflammatory drugs for the prevention of macular oedema after cataract surgery
Lim, BX, Lim, CHL, Lim, DK, et al. · Cochrane Database of Systematic Reviews · 2016 · Cochrane Library
Eyes and VisionAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
14
current version
GRADE rated
5
No studies
3
Included studies
NR
No studies 3 · 21.4%Ungraded 6 · 42.9%Very low 1 · 7.1%Low 4 · 28.6%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
NSAIDS plus steroids compared with steroids for the prevention of macular oedema after cataract surgery
Population: people having cataract surgery
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Poor vision due to MO at 3 months after surgery NSAIDS plus steroids vs steroids | RR 0.41 [0.23, 0.76] | 5 studies · 1360 participants | Low Downgraded: risk of bias, indirectness |
Poor vision due to MO at 12 months after surgery NSAIDS plus steroids vs steroids | RR 1.32 [0.09, 20.37] | 1 study · 88 participants | Very low Downgraded: risk of bias, imprecision |
Quality of life at 3 months after surgery NSAIDS plus steroids vs steroids | no estimate extracted | 1 study · 74 participants | Ungraded |
Central retinal thickness at 3 months after surgery; NSAIDS plus steroids vs steroids | no estimate extracted | 8 studies · 1021 participants | Ungraded |
Adverse effects NSAIDS plus steroids vs steroids | no estimate extracted | 18 studies · 18 participants | Ungraded |
MO at 3 months after cataract surgery, clinically symptomatic, NSAIDS plus steroids vs steroids | RR 0.4 | 21 studies · 3638 participants | Low Downgraded: risk of bias, publication bias |
BCVA at 3 months after surgery; NSAIDS plus steroids vs steroids | no estimate extracted | 10 studies · 1158 participants | Ungraded |
NSAIDS compared with steroids for the prevention of macular oedema after cataract surgery
Population: people having cataract surgery
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Poor vision outcome due to MO at 3 months after surgery NSAIDS vs steroids | no estimate extracted | NR | No studies |
Poor vision outcome due to MO at 12 months after surgery NSAIDS vs steroids | no estimate extracted | NR | No studies |
Quality of life at 3 months after surgery NSAIDS vs steroids | no estimate extracted | NR | No studies |
Central retinal thickness at 3 months after surgery; NSAIDS vs steroids | no estimate extracted | 2 studies · 121 participants | Low Downgraded: risk of bias |
Adverse effects NSAIDS vs steroids | no estimate extracted | 4 studies · 488 participants | Ungraded |
MO at 3 months after cataract surgery; clinically symptomatic NSAIDS vs steroids | RR 0.27 [0.18, 0.41] | 5 studies · 520 participants | Low Downgraded: risk of bias, publication bias |
BCVA at 3 months after surgery; NSAIDS vs steroids | no estimate extracted | 3 studies · 220 participants | Ungraded |