Cochrane Review Group

Dementia and Cognitive Improvement

79 systematic reviews in Dementia and Cognitive Improvement ask 1,049 questions. 22.9% have no studies to answer them, 20.6% rest on very low certainty evidence and 29.5% reach moderate or high certainty.

Reviews

Questions

1,049

current versions

No studies

22.9%

Moderate or high

29.5%

No studies 240 · 22.9%Ungraded 31 · 3%Very low 216 · 20.6%Low 253 · 24.1%Moderate 238 · 22.7%High 71 · 6.8%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Search questions in Dementia and Cognitive Improvement

Thinnest evidence

All no studies and very low questions

Question	Effect	Evidence	Status / GRADE
Transcranial direct current stimulation (tDCS) vs sham tDCS Word retrieval · adults with primary progressive aphasia (PPA) Non‐pharmacological interventions for improving language and communication in people with primary… (2024) · Cochrane	no estimate extracted	NR	No studies
Active tDCS plus semantic and phonological word‐retrieval training vs sham tDCS plus semantic and phonological word‐retrieval training Adverse events · adults with primary progressive aphasia (PPA) Non‐pharmacological interventions for improving language and communication in people with primary… (2024) · Cochrane	no estimate extracted	2 studies · 37 participants	Very low
Active tDCS plus phonological word‐retrieval training vs sham tDCS plus phonological word‐retrieval training Word retrieval · adults with primary progressive aphasia (PPA) Non‐pharmacological interventions for improving language and communication in people with primary… (2024) · Cochrane	no estimate extracted	1 study · 6 participants	Very low
Active tDCS plus phonological word‐retrieval training vs sham tDCS plus phonological word‐retrieval training Overall language abilities · adults with primary progressive aphasia (PPA) Non‐pharmacological interventions for improving language and communication in people with primary… (2024) · Cochrane	no estimate extracted	NR	No studies
Active tDCS plus phonological word‐retrieval training vs sham tDCS plus phonological word‐retrieval training Overall cognitive assessment · adults with primary progressive aphasia (PPA) Non‐pharmacological interventions for improving language and communication in people with primary… (2024) · Cochrane	no estimate extracted	NR	No studies
Active tDCS plus phonological word‐retrieval training vs sham tDCS plus phonological word‐retrieval training Quality of life · adults with primary progressive aphasia (PPA) Non‐pharmacological interventions for improving language and communication in people with primary… (2024) · Cochrane	no estimate extracted	NR	No studies
Active tDCS plus phonological word‐retrieval training vs sham tDCS plus phonological word‐retrieval training Adverse events · adults with primary progressive aphasia (PPA) Non‐pharmacological interventions for improving language and communication in people with primary… (2024) · Cochrane	no estimate extracted	1 study · 6 participants	Very low
Active tDCS plus semantic word‐retrieval training vs sham tDCS plus semantic word‐retrieval training Word retrieval · adults with primary progressive aphasia (PPA) Non‐pharmacological interventions for improving language and communication in people with primary… (2024) · Cochrane	no estimate extracted	1 study · 3 participants	Very low
Active tDCS plus semantic word‐retrieval training vs sham tDCS plus semantic word‐retrieval training Overall language abilities · adults with primary progressive aphasia (PPA) Non‐pharmacological interventions for improving language and communication in people with primary… (2024) · Cochrane	no estimate extracted	NR	No studies
Active tDCS plus semantic word‐retrieval training vs sham tDCS plus semantic word‐retrieval training Overall cognitive assessment · adults with primary progressive aphasia (PPA) Non‐pharmacological interventions for improving language and communication in people with primary… (2024) · Cochrane	no estimate extracted	NR	No studies
Active tDCS plus semantic word‐retrieval training vs sham tDCS plus semantic word‐retrieval training Quality of life · adults with primary progressive aphasia (PPA) Non‐pharmacological interventions for improving language and communication in people with primary… (2024) · Cochrane	no estimate extracted	NR	No studies
Transcranial direct current stimulation (tDCS) vs sham tDCS Overall language abilities · adults with primary progressive aphasia (PPA) Non‐pharmacological interventions for improving language and communication in people with primary… (2024) · Cochrane	no estimate extracted	1 study · 15 participants	Very low

Reviews 79

Antipsychotics for treatment of delirium in hospitalised non‐ICU patients

Burry, L, Mehta, S, et al. · Cochrane Database of Systematic Reviews · 2018

Dementia and Cognitive Improvement

Thinnest evidence

Reviews 79

Antipsychotics for treatment of delirium in hospitalised non‐ICU patients

Withdrawal versus continuation of long‐term antipsychotic drug use for behavioural and psychological symptoms in older people with dementia

Traditional Chinese herbal medicine for vascular dementia

Art therapy for people with dementia

Modifying the consistency of food and fluids for swallowing difficulties in dementia

Environmental and behavioural modifications for improving food and fluid intake in people with dementia

Vitamin and mineral supplementation for preventing dementia or delaying cognitive decline in people with mild cognitive impairment

Vitamin and mineral supplementation for maintaining cognitive function in cognitively healthy people in mid and late life

Pharmacological interventions for apathy in Alzheimer's disease

Cholinesterase inhibitors for the treatment of delirium in non‐ICU settings

Mindfulness‐based stress reduction for family carers of people with dementia

Vitamin E for Alzheimer's dementia and mild cognitive impairment

Effect of the treatment of Type 2 diabetes mellitus on the development of cognitive impairment and dementia

L‐carnitine for cognitive enhancement in people without cognitive impairment

Statins for the prevention of dementia

Interventions for preventing delirium in hospitalised non‐ICU patients

Omega‐3 fatty acids for the treatment of dementia

Antihypertensive withdrawal for the prevention of cognitive decline

Rivastigmine for Alzheimer's disease

Exercise programs for people with dementia

Case management approaches to home support for people with dementia

Pharmacotherapy for chronic cognitive impairment in traumatic brain injury

Cholinesterase inhibitors for rarer dementias associated with neurological conditions

Latrepirdine for Alzheimer's disease

Respite care for people with dementia and their carers