Cochrane Review Group

Dementia and Cognitive Improvement

79 systematic reviews in Dementia and Cognitive Improvement ask 1,049 questions. 22.9% have no studies to answer them, 20.6% rest on very low certainty evidence and 29.5% reach moderate or high certainty.

Reviews

Questions

1,049

current versions

No studies

22.9%

Moderate or high

29.5%

No studies 240 · 22.9%Ungraded 31 · 3%Very low 216 · 20.6%Low 253 · 24.1%Moderate 238 · 22.7%High 71 · 6.8%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Search questions in Dementia and Cognitive Improvement

Thinnest evidence

All no studies and very low questions

Question	Effect	Evidence	Status / GRADE
Transcranial direct current stimulation (tDCS) vs sham tDCS Word retrieval · adults with primary progressive aphasia (PPA) Non‐pharmacological interventions for improving language and communication in people with primary… (2024) · Cochrane	no estimate extracted	NR	No studies
Active tDCS plus semantic and phonological word‐retrieval training vs sham tDCS plus semantic and phonological word‐retrieval training Adverse events · adults with primary progressive aphasia (PPA) Non‐pharmacological interventions for improving language and communication in people with primary… (2024) · Cochrane	no estimate extracted	2 studies · 37 participants	Very low
Active tDCS plus phonological word‐retrieval training vs sham tDCS plus phonological word‐retrieval training Word retrieval · adults with primary progressive aphasia (PPA) Non‐pharmacological interventions for improving language and communication in people with primary… (2024) · Cochrane	no estimate extracted	1 study · 6 participants	Very low
Active tDCS plus phonological word‐retrieval training vs sham tDCS plus phonological word‐retrieval training Overall language abilities · adults with primary progressive aphasia (PPA) Non‐pharmacological interventions for improving language and communication in people with primary… (2024) · Cochrane	no estimate extracted	NR	No studies
Active tDCS plus phonological word‐retrieval training vs sham tDCS plus phonological word‐retrieval training Overall cognitive assessment · adults with primary progressive aphasia (PPA) Non‐pharmacological interventions for improving language and communication in people with primary… (2024) · Cochrane	no estimate extracted	NR	No studies
Active tDCS plus phonological word‐retrieval training vs sham tDCS plus phonological word‐retrieval training Quality of life · adults with primary progressive aphasia (PPA) Non‐pharmacological interventions for improving language and communication in people with primary… (2024) · Cochrane	no estimate extracted	NR	No studies
Active tDCS plus phonological word‐retrieval training vs sham tDCS plus phonological word‐retrieval training Adverse events · adults with primary progressive aphasia (PPA) Non‐pharmacological interventions for improving language and communication in people with primary… (2024) · Cochrane	no estimate extracted	1 study · 6 participants	Very low
Active tDCS plus semantic word‐retrieval training vs sham tDCS plus semantic word‐retrieval training Word retrieval · adults with primary progressive aphasia (PPA) Non‐pharmacological interventions for improving language and communication in people with primary… (2024) · Cochrane	no estimate extracted	1 study · 3 participants	Very low
Active tDCS plus semantic word‐retrieval training vs sham tDCS plus semantic word‐retrieval training Overall language abilities · adults with primary progressive aphasia (PPA) Non‐pharmacological interventions for improving language and communication in people with primary… (2024) · Cochrane	no estimate extracted	NR	No studies
Active tDCS plus semantic word‐retrieval training vs sham tDCS plus semantic word‐retrieval training Overall cognitive assessment · adults with primary progressive aphasia (PPA) Non‐pharmacological interventions for improving language and communication in people with primary… (2024) · Cochrane	no estimate extracted	NR	No studies
Active tDCS plus semantic word‐retrieval training vs sham tDCS plus semantic word‐retrieval training Quality of life · adults with primary progressive aphasia (PPA) Non‐pharmacological interventions for improving language and communication in people with primary… (2024) · Cochrane	no estimate extracted	NR	No studies
Transcranial direct current stimulation (tDCS) vs sham tDCS Overall language abilities · adults with primary progressive aphasia (PPA) Non‐pharmacological interventions for improving language and communication in people with primary… (2024) · Cochrane	no estimate extracted	1 study · 15 participants	Very low

Reviews 79

Multi‐domain interventions for the prevention of dementia and cognitive decline

Hafdi, M, Hoevenaar-Blom, MP, et al. · Cochrane Database of Systematic Reviews · 2021

Dementia and Cognitive Improvement

Thinnest evidence

Reviews 79

Multi‐domain interventions for the prevention of dementia and cognitive decline

Diagnostic test accuracy of telehealth assessment for dementia and mild cognitive impairment

Aromatherapy for dementia

Pharmacotherapies for sleep disturbances in dementia

Structural magnetic resonance imaging for the early diagnosis of dementia due to Alzheimer's disease in people with mild cognitive impairment

Personally tailored activities for improving psychosocial outcomes for people with dementia in community settings

Enhanced rehabilitation and care models for adults with dementia following hip fracture surgery

Aspirin and other non‐steroidal anti‐inflammatory drugs for the prevention of dementia

Souvenaid for Alzheimer's disease

Simulated presence therapy for dementia

Cognitive training interventions for dementia and mild cognitive impairment in Parkinson’s disease

Computerised cognitive training for 12 or more weeks for maintaining cognitive function in cognitively healthy people in late life

Benzodiazepines for treatment of patients with delirium excluding those who are cared for in an intensive care unit

Memantine for dementia

Cerebrolysin for vascular dementia

Interventions for preventing delirium in older people in institutional long‐term care

Computerised cognitive training for maintaining cognitive function in cognitively healthy people in midlife

Computerised cognitive training for preventing dementia in people with mild cognitive impairment

Cognitive training for people with mild to moderate dementia

Animal‐assisted therapy for dementia

Reminiscence therapy for dementia

Donepezil for dementia due to Alzheimer's disease

Music‐based therapeutic interventions for people with dementia

Antidepressants for treating depression in dementia

Valproate preparations for agitation in dementia