Cochrane Review Group

Dementia and Cognitive Improvement

79 systematic reviews in Dementia and Cognitive Improvement ask 1,049 questions. 22.9% have no studies to answer them, 20.6% rest on very low certainty evidence and 29.5% reach moderate or high certainty.

Reviews

Questions

1,049

current versions

No studies

22.9%

Moderate or high

29.5%

No studies 240 · 22.9%Ungraded 31 · 3%Very low 216 · 20.6%Low 253 · 24.1%Moderate 238 · 22.7%High 71 · 6.8%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Search questions in Dementia and Cognitive Improvement

Thinnest evidence

All no studies and very low questions

Question	Effect	Evidence	Status / GRADE
Transcranial direct current stimulation (tDCS) vs sham tDCS Word retrieval · adults with primary progressive aphasia (PPA) Non‐pharmacological interventions for improving language and communication in people with primary… (2024) · Cochrane	no estimate extracted	NR	No studies
Active tDCS plus semantic and phonological word‐retrieval training vs sham tDCS plus semantic and phonological word‐retrieval training Adverse events · adults with primary progressive aphasia (PPA) Non‐pharmacological interventions for improving language and communication in people with primary… (2024) · Cochrane	no estimate extracted	2 studies · 37 participants	Very low
Active tDCS plus phonological word‐retrieval training vs sham tDCS plus phonological word‐retrieval training Word retrieval · adults with primary progressive aphasia (PPA) Non‐pharmacological interventions for improving language and communication in people with primary… (2024) · Cochrane	no estimate extracted	1 study · 6 participants	Very low
Active tDCS plus phonological word‐retrieval training vs sham tDCS plus phonological word‐retrieval training Overall language abilities · adults with primary progressive aphasia (PPA) Non‐pharmacological interventions for improving language and communication in people with primary… (2024) · Cochrane	no estimate extracted	NR	No studies
Active tDCS plus phonological word‐retrieval training vs sham tDCS plus phonological word‐retrieval training Overall cognitive assessment · adults with primary progressive aphasia (PPA) Non‐pharmacological interventions for improving language and communication in people with primary… (2024) · Cochrane	no estimate extracted	NR	No studies
Active tDCS plus phonological word‐retrieval training vs sham tDCS plus phonological word‐retrieval training Quality of life · adults with primary progressive aphasia (PPA) Non‐pharmacological interventions for improving language and communication in people with primary… (2024) · Cochrane	no estimate extracted	NR	No studies
Active tDCS plus phonological word‐retrieval training vs sham tDCS plus phonological word‐retrieval training Adverse events · adults with primary progressive aphasia (PPA) Non‐pharmacological interventions for improving language and communication in people with primary… (2024) · Cochrane	no estimate extracted	1 study · 6 participants	Very low
Active tDCS plus semantic word‐retrieval training vs sham tDCS plus semantic word‐retrieval training Word retrieval · adults with primary progressive aphasia (PPA) Non‐pharmacological interventions for improving language and communication in people with primary… (2024) · Cochrane	no estimate extracted	1 study · 3 participants	Very low
Active tDCS plus semantic word‐retrieval training vs sham tDCS plus semantic word‐retrieval training Overall language abilities · adults with primary progressive aphasia (PPA) Non‐pharmacological interventions for improving language and communication in people with primary… (2024) · Cochrane	no estimate extracted	NR	No studies
Active tDCS plus semantic word‐retrieval training vs sham tDCS plus semantic word‐retrieval training Overall cognitive assessment · adults with primary progressive aphasia (PPA) Non‐pharmacological interventions for improving language and communication in people with primary… (2024) · Cochrane	no estimate extracted	NR	No studies
Active tDCS plus semantic word‐retrieval training vs sham tDCS plus semantic word‐retrieval training Quality of life · adults with primary progressive aphasia (PPA) Non‐pharmacological interventions for improving language and communication in people with primary… (2024) · Cochrane	no estimate extracted	NR	No studies
Transcranial direct current stimulation (tDCS) vs sham tDCS Overall language abilities · adults with primary progressive aphasia (PPA) Non‐pharmacological interventions for improving language and communication in people with primary… (2024) · Cochrane	no estimate extracted	1 study · 15 participants	Very low

Reviews 79

Non‐pharmacological interventions for improving language and communication in people with primary progressive aphasia

Roheger, M, Riemann, S, et al. · Cochrane Database of Systematic Reviews · 2024

Dementia and Cognitive Improvement

Thinnest evidence

Reviews 79

Non‐pharmacological interventions for improving language and communication in people with primary progressive aphasia

Cognitive stimulation to improve cognitive functioning in people with dementia

Interventions for preventing and reducing the use of physical restraints for older people in all long‐term care settings

Psychosocial interventions for reducing antipsychotic medication in care home residents

Personally tailored activities for improving psychosocial outcomes for people with dementia in long‐term care

Dance movement therapy for dementia

Non‐pharmacological interventions for sleep disturbances in people with dementia

Cognitive rehabilitation for people with mild to moderate dementia

Multi‐domain prognostic models used in middle‐aged adults without known cognitive impairment for predicting subsequent dementia

Anticholinergic deprescribing interventions for reducing risk of cognitive decline or dementia in older adults with and without prior cognitive impairment

Psychological treatments for depression and anxiety in dementia and mild cognitive impairment

Antithrombotic therapy to prevent cognitive decline in people with small vessel disease on neuroimaging but without dementia

Interventions for preventing and reducing the use of physical restraints of older people in general hospital settings

Algorithm‐based pain management for people with dementia in nursing homes

Anticholinergic burden for prediction of cognitive decline or neuropsychiatric symptoms in older adults with mild cognitive impairment or dementia

Pharmacological treatment of hypertension in people without prior cerebrovascular disease for the prevention of cognitive impairment and dementia

Remotely delivered information, training and support for informal caregivers of people with dementia

Withdrawal or continuation of cholinesterase inhibitors or memantine or both, in people with dementia

Palliative care interventions in advanced dementia

Cannabinoids for the treatment of dementia

Antipsychotics for agitation and psychosis in people with Alzheimer's disease and vascular dementia

Cholinesterase inhibitors for vascular dementia and other vascular cognitive impairments: a network meta‐analysis

Non‐pharmacological interventions for preventing delirium in hospitalised non‐ICU patients

Enteral tube feeding for people with severe dementia

Anticholinergic burden (prognostic factor) for prediction of dementia or cognitive decline in older adults with no known cognitive syndrome