Cochrane · systematic review · CD013503

Enteral tube feeding for people with severe dementia

Davies, N, Barrado-Martín, Y, Vickerstaff, V, et al. · Cochrane Database of Systematic Reviews · 2021 · Cochrane Library

SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
18
current version
GRADE rated
10
No studies
8
Included studies
NR
No studies 8 · 44.4%Ungraded 0 · 0%Very low 8 · 44.4%Low 1 · 5.6%Moderate 1 · 5.6%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

PEG compared to no enteral tube feeding for people with severe dementia

Population: people with severe dementia
6 questions
OutcomeEffectEvidenceStatus / GRADE
Survival timea
PEG vs no enteral tube feeding
no estimate extracted4 studies · 36816 participantsLow
Downgraded: risk of bias, imprecision, inconsistency
Mortalityc
PEG vs no enteral tube feeding
no estimate extracted2 studies · 6445 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency
Quality of life
PEG vs no enteral tube feeding
no estimate extractedNRNo studies
Pressure ulcerse
PEG vs no enteral tube feeding
no estimate extracted1 study · 4421 participantsModerate
Downgraded: risk of bias, imprecision, inconsistency
Pain and comfort
PEG vs no enteral tube feeding
no estimate extractedNRNo studies
Improvement of nutritional status
PEG vs no enteral tube feeding
no estimate extractedNRNo studies

Nasogastric tubes compared to no enteral tube feeding for people with severe dementia

Population: people with severe dementia
6 questions
OutcomeEffectEvidenceStatus / GRADE
Survival time
Nasogastric tubes vs no enteral tube feeding
no estimate extractedNRNo studies
Mortalitya
Nasogastric tubes vs no enteral tube feeding
no estimate extracted2 studies · 236 participantsVery low
Downgraded: risk of bias, inconsistency
Quality of life
Nasogastric tubes vs no enteral tube feeding
no estimate extractedNRNo studies
Pressure ulcers
Nasogastric tubes vs no enteral tube feeding
no estimate extractedNRNo studies
Pain and comfort
Nasogastric tubes vs no enteral tube feeding
no estimate extractedNRNo studies
Improvement of nutritional parameters (nutrition)d
Nasogastric tubes vs no enteral tube feeding
no estimate extracted1 study · 67 participantsVery low
Downgraded: risk of bias, inconsistency

Mixed (nasogastric or PEG) or unspecified enteral tube feeding for people with severe dementia

Population: people with severe dementia
6 questions
OutcomeEffectEvidenceStatus / GRADE
Survival timea
no estimate extracted4 studies · 1696 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency
Mortalityd
no estimate extracted2 studies · 234 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency
Quality of Life
no estimate extractedNRNo studies
Pressure ulcersf
no estimate extracted3 studies · 351 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency
Pain and comforth No
no estimate extracted1 study · 117 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency
Improvement of nutritional parameters (Nutrition)j
no estimate extracted1 study · 167 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency