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Search review questions

Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

1,049 questions in 79 reviews · Dementia and Cognitive Improvement

current versions
No studies 240 · 22.9%Ungraded 31 · 3%Very low 216 · 20.6%Low 253 · 24.1%Moderate 238 · 22.7%High 71 · 6.8%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
Transcranial direct current stimulation (tDCS) vs sham tDCS
Word retrieval · adults with primary progressive aphasia (PPA)
Non‐pharmacological interventions for improving language and communication in people with primary… (2024) · Cochrane
no estimate extractedNRNo studies
Active tDCS plus semantic and phonological word‐retrieval training vs sham tDCS plus semantic and phonological word‐retrieval training
Adverse events · adults with primary progressive aphasia (PPA)
Non‐pharmacological interventions for improving language and communication in people with primary… (2024) · Cochrane
no estimate extracted2 studies · 37 participantsVery low
Active tDCS plus phonological word‐retrieval training vs sham tDCS plus phonological word‐retrieval training
Word retrieval · adults with primary progressive aphasia (PPA)
Non‐pharmacological interventions for improving language and communication in people with primary… (2024) · Cochrane
no estimate extracted1 study · 6 participantsVery low
Active tDCS plus phonological word‐retrieval training vs sham tDCS plus phonological word‐retrieval training
Overall language abilities · adults with primary progressive aphasia (PPA)
Non‐pharmacological interventions for improving language and communication in people with primary… (2024) · Cochrane
no estimate extractedNRNo studies
Active tDCS plus phonological word‐retrieval training vs sham tDCS plus phonological word‐retrieval training
Overall cognitive assessment · adults with primary progressive aphasia (PPA)
Non‐pharmacological interventions for improving language and communication in people with primary… (2024) · Cochrane
no estimate extractedNRNo studies
Active tDCS plus phonological word‐retrieval training vs sham tDCS plus phonological word‐retrieval training
Quality of life · adults with primary progressive aphasia (PPA)
Non‐pharmacological interventions for improving language and communication in people with primary… (2024) · Cochrane
no estimate extractedNRNo studies
Active tDCS plus phonological word‐retrieval training vs sham tDCS plus phonological word‐retrieval training
Adverse events · adults with primary progressive aphasia (PPA)
Non‐pharmacological interventions for improving language and communication in people with primary… (2024) · Cochrane
no estimate extracted1 study · 6 participantsVery low
Active tDCS plus semantic word‐retrieval training vs sham tDCS plus semantic word‐retrieval training
Word retrieval · adults with primary progressive aphasia (PPA)
Non‐pharmacological interventions for improving language and communication in people with primary… (2024) · Cochrane
no estimate extracted1 study · 3 participantsVery low
Active tDCS plus semantic word‐retrieval training vs sham tDCS plus semantic word‐retrieval training
Overall language abilities · adults with primary progressive aphasia (PPA)
Non‐pharmacological interventions for improving language and communication in people with primary… (2024) · Cochrane
no estimate extractedNRNo studies
Active tDCS plus semantic word‐retrieval training vs sham tDCS plus semantic word‐retrieval training
Overall cognitive assessment · adults with primary progressive aphasia (PPA)
Non‐pharmacological interventions for improving language and communication in people with primary… (2024) · Cochrane
no estimate extractedNRNo studies
Active tDCS plus semantic word‐retrieval training vs sham tDCS plus semantic word‐retrieval training
Quality of life · adults with primary progressive aphasia (PPA)
Non‐pharmacological interventions for improving language and communication in people with primary… (2024) · Cochrane
no estimate extractedNRNo studies
Transcranial direct current stimulation (tDCS) vs sham tDCS
Overall language abilities · adults with primary progressive aphasia (PPA)
Non‐pharmacological interventions for improving language and communication in people with primary… (2024) · Cochrane
no estimate extracted1 study · 15 participantsVery low
Active tDCS plus semantic word‐retrieval training vs sham tDCS plus semantic word‐retrieval training
Adverse events · adults with primary progressive aphasia (PPA)
Non‐pharmacological interventions for improving language and communication in people with primary… (2024) · Cochrane
no estimate extracted1 study · 3 participantsVery low
Repetitive transcranial magnetic stimulation (rTMS) vs active control‐site rTMS
Word retrieval · adults with primary progressive aphasia (PPA)
Non‐pharmacological interventions for improving language and communication in people with primary… (2024) · Cochrane
no estimate extractedNRNo studies
Repetitive transcranial magnetic stimulation (rTMS) vs active control‐site rTMS
Overall language abilities · adults with primary progressive aphasia (PPA)
Non‐pharmacological interventions for improving language and communication in people with primary… (2024) · Cochrane
no estimate extracted1 study · 27 participantsVery low
Repetitive transcranial magnetic stimulation (rTMS) vs active control‐site rTMS
Overall cognitive assessment · adults with primary progressive aphasia (PPA)
Non‐pharmacological interventions for improving language and communication in people with primary… (2024) · Cochrane
no estimate extracted1 study · 27 participantsVery low
Repetitive transcranial magnetic stimulation (rTMS) vs active control‐site rTMS
Quality of life · adults with primary progressive aphasia (PPA)
Non‐pharmacological interventions for improving language and communication in people with primary… (2024) · Cochrane
no estimate extractedNRNo studies
Repetitive transcranial magnetic stimulation (rTMS) vs active control‐site rTMS
Adverse events · adults with primary progressive aphasia (PPA)
Non‐pharmacological interventions for improving language and communication in people with primary… (2024) · Cochrane
no estimate extracted1 study · 27 participantsVery low
Transcranial direct current stimulation (tDCS) vs sham tDCS
Overall cognitive assessment · adults with primary progressive aphasia (PPA)
Non‐pharmacological interventions for improving language and communication in people with primary… (2024) · Cochrane
no estimate extractedNRNo studies
Transcranial direct current stimulation (tDCS) vs sham tDCS
Quality of life · adults with primary progressive aphasia (PPA)
Non‐pharmacological interventions for improving language and communication in people with primary… (2024) · Cochrane
no estimate extractedNRNo studies
Transcranial direct current stimulation (tDCS) vs sham tDCS
Adverse events · adults with primary progressive aphasia (PPA)
Non‐pharmacological interventions for improving language and communication in people with primary… (2024) · Cochrane
no estimate extracted1 study · 15 participantsVery low
Active tDCS plus semantic and phonological word‐retrieval training vs sham tDCS plus semantic and phonological word‐retrieval training
Word retrieval · adults with primary progressive aphasia (PPA)
Non‐pharmacological interventions for improving language and communication in people with primary… (2024) · Cochrane
no estimate extracted4 studies · 93 participantsVery low
Active tDCS plus semantic and phonological word‐retrieval training vs sham tDCS plus semantic and phonological word‐retrieval training
Overall language abilities · adults with primary progressive aphasia (PPA)
Non‐pharmacological interventions for improving language and communication in people with primary… (2024) · Cochrane
no estimate extracted2 studies · 28 participantsVery low
Active tDCS plus semantic and phonological word‐retrieval training vs sham tDCS plus semantic and phonological word‐retrieval training
Overall cognitive assessment · adults with primary progressive aphasia (PPA)
Non‐pharmacological interventions for improving language and communication in people with primary… (2024) · Cochrane
no estimate extracted2 studies · 37 participantsVery low
Active tDCS plus semantic and phonological word‐retrieval training vs sham tDCS plus semantic and phonological word‐retrieval training
Quality of life · adults with primary progressive aphasia (PPA)
Non‐pharmacological interventions for improving language and communication in people with primary… (2024) · Cochrane
no estimate extracted1 study · 16 participantsVery low
Cognitive stimulation vs no cognitive stimulation (post‐treatment)
Cognition · people with dementia
Cognitive stimulation to improve cognitive functioning in people with dementia (2023) · Cochrane
no estimate extracted34 studies · 2340 participantsModerate
Group cognitive stimulation vs no cognitive stimulation (post‐treatment)
Communication and social interaction · people with dementia
Cognitive stimulation to improve cognitive functioning in people with dementia (2023) · Cochrane
no estimate extracted7 studies · 702 participantsHigh
Group cognitive stimulation vs no cognitive stimulation (post‐treatment)
Mood: self‐reported · people with dementia
Cognitive stimulation to improve cognitive functioning in people with dementia (2023) · Cochrane
no estimate extracted6 studies · 299 participantsModerate
Group cognitive stimulation vs no cognitive stimulation (post‐treatment)
Mood: interviewer/staff‐rated · people with dementia
Cognitive stimulation to improve cognitive functioning in people with dementia (2023) · Cochrane
no estimate extracted10 studies · 959 participantsModerate
Group cognitive stimulation vs no cognitive stimulation (post‐treatment)
Instrumental ADL · people with dementia
Cognitive stimulation to improve cognitive functioning in people with dementia (2023) · Cochrane
no estimate extracted8 studies · 687 participantsHigh
Group cognitive stimulation vs no cognitive stimulation (post‐treatment)
Behaviour that challenges · people with dementia
Cognitive stimulation to improve cognitive functioning in people with dementia (2023) · Cochrane
no estimate extracted8 studies · 754 participantsModerate
Cognitive stimulation vs no cognitive stimulation (post‐treatment)
Quality of Life: self‐report · people with dementia
Cognitive stimulation to improve cognitive functioning in people with dementia (2023) · Cochrane
no estimate extracted18 studies · 1584 participantsModerate
Cognitive stimulation vs no cognitive stimulation (post‐treatment)
Communication and social interaction · people with dementia
Cognitive stimulation to improve cognitive functioning in people with dementia (2023) · Cochrane
no estimate extracted7 studies · 702 participantsHigh
Cognitive stimulation vs no cognitive stimulation (post‐treatment)
Mood: self‐reported · people with dementia
Cognitive stimulation to improve cognitive functioning in people with dementia (2023) · Cochrane
no estimate extracted10 studies · 787 participantsHigh
Cognitive stimulation vs no cognitive stimulation (post‐treatment)
Mood: interviewer/staff‐rated · people with dementia
Cognitive stimulation to improve cognitive functioning in people with dementia (2023) · Cochrane
no estimate extracted11 studies · 1011 participantsLow
Cognitive stimulation vs no cognitive stimulation (post‐treatment)
Instrumental ADL · people with dementia
Cognitive stimulation to improve cognitive functioning in people with dementia (2023) · Cochrane
no estimate extracted13 studies · 1318 participantsHigh
Cognitive stimulation vs no cognitive stimulation (post‐treatment)
Behaviour that challenges · people with dementia
Cognitive stimulation to improve cognitive functioning in people with dementia (2023) · Cochrane
no estimate extracted12 studies · 1340 participantsModerate
Group cognitive stimulation vs no cognitive stimulation (post‐treatment)
Cognition · people with dementia
Cognitive stimulation to improve cognitive functioning in people with dementia (2023) · Cochrane
no estimate extracted27 studies · 1637 participantsModerate
Group cognitive stimulation vs no cognitive stimulation (post‐treatment)
Quality of Life: self‐report · people with dementia
Cognitive stimulation to improve cognitive functioning in people with dementia (2023) · Cochrane
no estimate extracted13 studies · 1058 participantsLow
Summary of findings table ‐ Organisational intervention vs usual care
Residents with at least one physical restraint · older people in all long‐term care settings
Interventions for preventing and reducing the use of physical restraints for older people in all long‐term… (2023) · Cochrane
RR 0.86 [0.76, 0.94]4 studies · 3849 participantsModerate
Summary of findings table ‐ Simple educational intervention vs usual care
Restraint intensity · older people in all long‐term care settings
Interventions for preventing and reducing the use of physical restraints for older people in all long‐term… (2023) · Cochrane
no estimate extracted1 study · 241 participantsModerate
Summary of findings table ‐ Simple educational intervention vs usual care
Residents with at least one fall · older people in all long‐term care settings
Interventions for preventing and reducing the use of physical restraints for older people in all long‐term… (2023) · Cochrane
no estimate extracted2 studies · 813 participantsLow
Summary of findings table ‐ Simple educational intervention vs usual care
Residents with at least one fall‐related serious injury · older people in all long‐term care settings
Interventions for preventing and reducing the use of physical restraints for older people in all long‐term… (2023) · Cochrane
no estimate extracted1 study · 463 participantsLow
Summary of findings table ‐ Simple educational intervention vs usual care
Residents with at least one psychotropic medication · older people in all long‐term care settings
Interventions for preventing and reducing the use of physical restraints for older people in all long‐term… (2023) · Cochrane
no estimate extracted5 studies · 1202 participantsVery low
Summary of findings table ‐ Providing information about the residents? fall risk vs usual care
Restraint use · older people in all long‐term care settings
Interventions for preventing and reducing the use of physical restraints for older people in all long‐term… (2023) · Cochrane
no estimate extracted1 study · 98 participantsLow
Summary of findings table ‐ Providing information about the residents? fall risk vs usual care
Serious adverse events related to the use of physical restraints ‐ not measured · older people in all long‐term care settings
Interventions for preventing and reducing the use of physical restraints for older people in all long‐term… (2023) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Providing information about the residents? fall risk vs usual care
Duration of physical restraint use ‐ not measured · older people in all long‐term care settings
Interventions for preventing and reducing the use of physical restraints for older people in all long‐term… (2023) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Providing information about the residents? fall risk vs usual care
Falls · older people in all long‐term care settings
Interventions for preventing and reducing the use of physical restraints for older people in all long‐term… (2023) · Cochrane
no estimate extracted1 study · 98 participantsLow
Summary of findings table ‐ Providing information about the residents? fall risk vs usual care
Fall‐related injuries ‐ not measured · older people in all long‐term care settings
Interventions for preventing and reducing the use of physical restraints for older people in all long‐term… (2023) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Providing information about the residents? fall risk vs usual care
Residents with at least one psychotropic medication ‐ not measured · older people in all long‐term care settings
Interventions for preventing and reducing the use of physical restraints for older people in all long‐term… (2023) · Cochrane
no estimate extractedNRNo studies