Cochrane · systematic review · CD013069

Cognitive training for people with mild to moderate dementia

Bahar‐Fuchs, A, Martyr, A, Goh, AMY, et al. · Cochrane Database of Systematic Reviews · 2019 · Cochrane Library

SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
28
current version
GRADE rated
24
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 4 · 14.3%Very low 12 · 42.9%Low 7 · 25%Moderate 5 · 17.9%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Cognitive training compared to control immediately post intervention for people with mild to moderate dementia

Population: people with mild to moderate dementia
7 questions
OutcomeEffectEvidenceStatus / GRADE
Change in a global measure of cognition (composite)
Cognitive training vs control immediately post intervention
no estimate extracted27 studies · 1389 participantsModerate
Downgraded: inconsistency
Change in a global measure of cognition
Cognitive training vs control immediately post intervention
no estimate extracted20 studies · 1288 participantsLow
Downgraded: risk of bias, imprecision, inconsistency, publication bias
Change in delayed memory
Cognitive training vs control immediately post intervention
no estimate extracted11 studies · 543 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency, publication bias
Change in participants' mood
Cognitive training vs control immediately post intervention
no estimate extracted8 studies · 577 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency, publication bias
Change in capacity for activities of daily living
Cognitive training vs control immediately post intervention
no estimate extracted10 studies · 687 participantsLow
Downgraded: risk of bias, imprecision, inconsistency, publication bias
Participant burden (retention rates)
Cognitive training vs control immediately post intervention
OR 0.73 [0.37, 1.43]17 studies · 1282 participantsLow
Downgraded: risk of bias, imprecision, inconsistency, publication bias
Change in mood and well‐being (caregiver)
Cognitive training vs control immediately post intervention
no estimate extracted1 study · 36 participantsModerate
Downgraded: risk of bias, imprecision, inconsistency, publication bias

Cognitive training compared to control in the medium term (3 to 12 months post intervention) for people with mild to moderate dementia

Population: people with mild to moderate dementia
7 questions
OutcomeEffectEvidenceStatus / GRADE
Change in a global measure of cognition (composite)
Cognitive training vs control
no estimate extracted8 studies · 387 participantsVery low
Downgraded: risk of bias
Change on global cognition (screening) (Global cog)
Cognitive training vs control
no estimate extracted6 studies · 387 participantsVery low
Downgraded: risk of bias
Change in disease progression
Cognitive training vs control
no estimate extracted3 studies · 98 participantsVery low
Downgraded: risk of bias
Change in delayed memory
Cognitive training vs control
no estimate extracted4 studies · 253 participantsVery low
Downgraded: risk of bias
Change in capacity for activities of daily living
Cognitive training vs control
no estimate extracted3 studies · 64 participantsLow
Downgraded: risk of bias, imprecision, inconsistency
Change in participants' mood
Cognitive training vs control
no estimate extracted2 studies · 30 participantsLow
Downgraded: risk of bias, imprecision, inconsistency
Change in mood and well‐being (caregiver)
Cognitive training vs control
no estimate extracted0 studies · 0 participantsUngraded

Cognitive training compared to alternative treatment immediately post intervention for people with mild to moderate dementia

Population: people with mild to moderate dementia
7 questions
OutcomeEffectEvidenceStatus / GRADE
Change in a global measure of cognition (composite)
Cognitive training vs alternative treatment immediately post intervention
no estimate extracted7 studies · 769 participantsLow
Downgraded: imprecision
Change in a global measure of cognition
Cognitive training vs alternative treatment immediately post intervention
no estimate extracted7 studies · 724 participantsVery low
Downgraded: imprecision
Change in delayed memory
Cognitive training vs alternative treatment immediately post intervention
no estimate extracted3 studies · 147 participantsVery low
Downgraded: imprecision, inconsistency
Change in participants' mood
Cognitive training vs alternative treatment immediately post intervention
no estimate extracted3 studies · 543 participantsModerate
Downgraded: imprecision, inconsistency
Change in capacity for activities of daily living
Cognitive training vs alternative treatment immediately post intervention
no estimate extracted3 studies · 525 participantsModerate
Downgraded: imprecision, inconsistency
Participant burden (retention rates)
Cognitive training vs alternative treatment immediately post intervention
OR 0.78 [0.24, 2.57]4 studies · 639 participantsVery low
Downgraded: imprecision
Change in mood and well‐being (caregiver)
Cognitive training vs alternative treatment immediately post intervention
no estimate extracted1 study · 88 participantsModerate
Downgraded: imprecision, inconsistency

Cognitive training compared to alternative treatment in the medium term (3 to 12 months post intervention) for people with mild to moderate dementia

Population: people with mild to moderate dementia
7 questions
OutcomeEffectEvidenceStatus / GRADE
Change in a global measure of cognition (composite)
Cognitive training vs alternative treatment
no estimate extracted2 studies · 73 participantsVery low
Downgraded: imprecision
Change in a global measure of cognition
Cognitive training vs alternative treatment
no estimate extracted2 studies · 73 participantsVery low
Downgraded: imprecision
Change in disease progression
Cognitive training vs alternative treatment
no estimate extracted0 studies · 0 participantsUngraded
Change in delayed memory
Cognitive training vs alternative treatment
no estimate extracted2 studies · 73 participantsVery low
Downgraded: imprecision
Change in participants' mood
Cognitive training vs alternative treatment
no estimate extracted1 study · 39 participantsLow
Downgraded: imprecision
Change in capacity for activities of daily living
Cognitive training vs alternative treatment
no estimate extracted0 studies · 0 participantsUngraded
Change in mood and well‐being (caregiver)
Cognitive training vs alternative treatment
no estimate extracted0 studies · 0 participantsUngraded